TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP
暂无分享,去创建一个
E. Raz | L. Blackshaw | M. Corr | M. Gareau | Jihyung Lee | P. D. de Jong | Alexandra R. Harris | M. Peiris | S. Bertin | Naoki Takahashi | D. S. Herdman | A. Paniagua
[1] N. Bottini,et al. Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis. , 2014, The Journal of clinical investigation.
[2] H. Fujino,et al. TRPM8 has a key role in experimental colitis‐induced visceral hyperalgesia in mice , 2014, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[3] V. Cerovic,et al. Intestinal macrophages and dendritic cells: what's the difference? , 2014, Trends in immunology.
[4] S. Frye,et al. The Lipid Kinase PIP5K1C Regulates Pain Signaling and Sensitization , 2014, Neuron.
[5] J. Fierer,et al. Altered expression and localization of ion transporters contribute to diarrhea in mice with Salmonella-induced enteritis. , 2013, Gastroenterology.
[6] W. Agace,et al. Dendritic cell subsets in the intestinal lamina propria: Ontogeny and function , 2013, European journal of immunology.
[7] D. McKemy,et al. TRPM8 activation attenuates inflammatory responses in mouse models of colitis , 2013, Proceedings of the National Academy of Sciences.
[8] W. Krajewska,et al. Transient Receptor Potential Vanilloid 4 blockade protects against experimental colitis in mice: a new strategy for inflammatory bowel diseases treatment? , 2012, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[9] C. Belmonte,et al. Direct inhibition of the cold-activated TRPM8 ion channel by Gαq , 2012, Nature Cell Biology.
[10] P. Insel,et al. Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets. , 2012, The Journal of clinical investigation.
[11] M. Neurath,et al. The proximodistal aggravation of colitis depends on substance P released from TRPV1-expressing sensory neurons , 2012, Journal of Gastroenterology.
[12] A. A. Romanovsky,et al. Pharmacological Blockade of the Cold Receptor TRPM8 Attenuates Autonomic and Behavioral Cold Defenses and Decreases Deep Body Temperature , 2012, The Journal of Neuroscience.
[13] H. Hammad,et al. The neuropeptide calcitonin gene‐related peptide affects allergic airway inflammation by modulating dendritic cell function , 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[14] M. Neurath,et al. TRPA1 and substance P mediate colitis in mice. , 2011, Gastroenterology.
[15] Qi Li,et al. Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. , 2011, The Journal of allergy and clinical immunology.
[16] Jing Yang,et al. A novel role for TRPM8 in visceral afferent function , 2011, PAIN®.
[17] Hiroshi Yamamoto,et al. Calcitonin Gene-Related Peptide Is an Important Regulator of Cutaneous Immunity: Effect on Dendritic Cell and T Cell Functions , 2011, The Journal of Immunology.
[18] J. Fisher. TRPM8 and dyspnea: from the frigid and fascinating past to the cool future? , 2011, Current opinion in pharmacology.
[19] M. Neurath,et al. Role of sensory neurons in colitis: increasing evidence for a neuroimmune link in the gut. , 2011, Inflammatory bowel diseases.
[20] Sheng-Nan Wu,et al. Characterization of TRPM8-Like Channels Activated by the Cooling Agent Icilin in the Macrophage Cell Line RAW 264.7 , 2011, The Journal of Membrane Biology.
[21] Kinzo Matsumoto,et al. Distribution of transient receptor potential vanilloid 1 channel-expressing nerve fibers in mouse rectal and colonic enteric nervous system: relationship to peptidergic and nitrergic neurons , 2011, Neuroscience.
[22] L. Eckmann,et al. Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9–driven antiinflammatory cytokine production , 2010, The Journal of experimental medicine.
[23] Moe Tsutsumi,et al. Topical application of TRPM8 agonists accelerates skin permeability barrier recovery and reduces epidermal proliferation induced by barrier insult: role of cold‐sensitive TRP receptors in epidermal permeability barrier homoeostasis , 2010, Experimental dermatology.
[24] E. Pintér,et al. The Role of Transient Receptor Potential Vanilloid 1 (Trpv1) Receptors in Dextran Sulfate-Induced Colitis in Mice , 2010, Journal of Molecular Neuroscience.
[25] Jongdae Lee,et al. ERK activation drives intestinal tumorigenesis in Apcmin/+ mice , 2010, Nature Medicine.
[26] U. Yrlid,et al. Subsets of migrating intestinal dendritic cells , 2010, Immunological reviews.
[27] B. Holzmann,et al. The Neuropeptide Calcitonin Gene-related Peptide Causes Repression of Tumor Necrosis Factor-α Transcription and Suppression of ATF-2 Promoter Recruitment in Toll-like Receptor-stimulated Dendritic Cells♦ , 2009, The Journal of Biological Chemistry.
[28] L. Blackshaw,et al. TRP channels: new targets for visceral pain , 2009, Gut.
[29] T. Akasu,et al. Expression of the TRPM8-immunoreactivity in dorsal root ganglion neurons innervating the rat urinary bladder , 2009, Neuroscience Research.
[30] P. Zygmunt,et al. Transient receptor potential vanilloid 1, vanilloid 2 and melastatin 8 immunoreactive nerve fibers in human skin from individuals with and without Norrbottnian congenital insensitivity to pain , 2009, Neuroscience.
[31] L. Blackshaw,et al. Role of TRPV1 in high-threshold rat colonic splanchnic afferents is revealed by inflammation , 2009, Neuroscience Letters.
[32] J. Weinstock,et al. Absence of the SP/SP Receptor Circuitry in the Substance P-Precursor Knockout Mice or SP Receptor, Neurokinin (NK)1 Knockout Mice Leads to an Inhibited Cytokine Response in Granulomas Associated with Murine Taenia crassiceps Infection , 2008, The Journal of parasitology.
[33] J. Bornstein,et al. Distinct chemical classes of medium-sized transient receptor potential channel vanilloid 1-immunoreactive dorsal root ganglion neurons innervate the adult mouse jejunum and colon , 2008, Neuroscience.
[34] R. Penner,et al. TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration , 2008, Nature Medicine.
[35] A. Patapoutian,et al. Visualizing Cold Spots: TRPM8-Expressing Sensory Neurons and Their Projections , 2008, The Journal of Neuroscience.
[36] Wendy M. Knowlton,et al. Diversity in the Neural Circuitry of Cold Sensing Revealed by Genetic Axonal Labeling of Transient Receptor Potential Melastatin 8 Neurons , 2007, The Journal of Neuroscience.
[37] Steffen Jung,et al. Conventional dendritic cells regulate the outcome of colonic inflammation independently of T cells , 2007, Proceedings of the National Academy of Sciences.
[38] H. Okamoto,et al. Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice , 2007, Proceedings of the National Academy of Sciences.
[39] G. Holtmann,et al. Increased visceral sensitivity to capsaicin after DSS-induced colitis in mice: spinal cord c-Fos expression and behavior. , 2007, American journal of physiology. Gastrointestinal and liver physiology.
[40] A. Miranda,et al. The role of transient receptor potential vanilloid 1 in mechanical and chemical visceral hyperalgesia following experimental colitis , 2007, Neuroscience.
[41] C. Molina,et al. Negative Regulation of TLR Responses by the Neuropeptide CGRP Is Mediated by the Transcriptional Repressor ICER1 , 2007, The Journal of Immunology.
[42] V. Di Marzo,et al. Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. , 2007, Experimental cell research.
[43] A. Patapoutian,et al. TRPM8 Is Required for Cold Sensation in Mice , 2007, Neuron.
[44] C. Schneider,et al. Stimulation of neuronal receptors, neuropeptides and cytokines during experimental oil of mustard colitis , 2007, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[45] D. Andersson,et al. Modulation of the Cold-Activated Channel TRPM8 by Lysophospholipids and Polyunsaturated Fatty Acids , 2007, The Journal of Neuroscience.
[46] G. MacQueen,et al. Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation , 2007, Gut.
[47] Stefan Wirtz,et al. Chemically induced mouse models of intestinal inflammation , 2007, Nature Protocols.
[48] H. Koerber,et al. Transient receptor potential vanilloid 1-immunopositive neurons in the mouse are more prevalent within colon afferents compared to skin and muscle afferents , 2006, Neuroscience.
[49] Y. Panchin,et al. Ca2+-independent Phospholipase A2-dependent Gating of TRPM8 by Lysophospholipids* , 2006, Journal of Biological Chemistry.
[50] M. Creer,et al. Potential role for mast cell tryptase in recruitment of inflammatory cells to endothelium. , 2005, American journal of physiology. Cell physiology.
[51] Shigeo Kobayashi,et al. TRPM8 protein localization in trigeminal ganglion and taste papillae. , 2005, Brain research. Molecular brain research.
[52] I. Michailidis,et al. PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain , 2005, Nature Neuroscience.
[53] M. D'Andrea,et al. Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium‐induced colitis in mice , 2004, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[54] P. Holzer. Vanilloid receptor TRPV1: hot on the tongue and inflaming the colon , 2004, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[55] A. Perraud,et al. Novel aspects of signaling and ion-homeostasis regulation in immunocytes. The TRPM ion channels and their potential role in modulating the immune response. , 2004, Molecular immunology.
[56] Lei Zhang,et al. Thermosensitive transient receptor potential channels in vagal afferent neurons of the mouse. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[57] R. Arsenescu,et al. Substance P Regulates Th1-Type Colitis in IL-10 Knockout Mice1 , 2003, The Journal of Immunology.
[58] P. McIntyre,et al. A TRP Channel that Senses Cold Stimuli and Menthol , 2002, Cell.
[59] D. McKemy,et al. Identification of a cold receptor reveals a general role for TRP channels in thermosensation , 2002, Nature.
[60] Lawrence O. Christensen,et al. Dictionary of Missouri Biography , 1999 .
[61] G. Adler,et al. Calcitonin gene-related peptide mediates the protective effect of sensory nerves in a model of colonic injury. , 1998, The Journal of pharmacology and experimental therapeutics.
[62] Moon Young,et al. United States Post Office , 1955 .
[63] M. Neurath,et al. Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis. , 2012, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
[64] J. Vinel,et al. Transient receptor potential vanilloid 4 activated inflammatory signals by intestinal epithelial cells and colitis in mice. , 2011, Gastroenterology.
[65] P. Holzer. TRP channels in the digestive system. , 2011, Current pharmaceutical biotechnology.
[66] M. Washington,et al. Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis. , 2008, Digestive diseases and sciences.
[67] J. A. Peters,et al. Transient receptor potential cation channels in disease. , 2007, Physiological reviews.
[68] M. Washington,et al. Protective Roles of α-Calcitonin and β-Calcitonin Gene-Related Peptide in Spontaneous and Experimentally Induced Colitis , 2007, Digestive Diseases and Sciences.
[69] R. Longstreth. The Buildings of Main Street: A Guide to American Commercial Architecture , 1987 .
[70] Marian M. Ohman. St. Francois County , 1980 .
[71] J. Poppeliers,et al. What Style Is It , 1978 .