Malignant solitary fibrous tumor of the nasal cavity.

Solitary fibrous tumors (SFTs) are unusual mesenchymal tumors that were first described as primary spindle-cell neoplasms of the pleura. These tumors have been described in many other locations, including the urogenital system, orbit, mediastinum, and upper respiratory tract. Twenty-two cases of an SFT of the paranasal sinuses and nasal cavity have been reported, but none described a malignant SFT extending through the anterior skull base. A 70-year-old man had a 6-month history of unilateral left-sided epiphora and nasal obstruction. Computed tomography and magnetic resonance imaging showed a large left-sided nasal cavity mass with extension into the left extraconal orbit and intracranial extension through the left cribriform plate and ethmoid roof. The patient underwent preoperative embolization of the internal maxillary artery and a subsequent anterior craniofacial resection via a midfacial degloving approach and a left anterior craniotomy. Histopathological analysis of the specimen was consistent with a malignant SFT.

[1]  G. Nai,et al.  Solitary fibrous tumor of the nasal cavity , 2009, Brazilian journal of otorhinolaryngology.

[2]  J. Tu,et al.  Malignant Solitary Fibrous Tumor of the Hypopharynx With Dysphagia , 2005, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[3]  J. Nesland,et al.  Solitary fibrous tumour of the thyroid: Clinicopathological, immunohistochemical and ultrastructural study of three cases , 2005, Virchows Archiv A.

[4]  M. Bernal-Sprekelsen,et al.  Laryngeal solitary fibrous tumor treated with CO2 laser excision: case report , 2005, European Archives of Oto-Rhino-Laryngology and Head & Neck.

[5]  K. Moe,et al.  Nasal solitary fibrous tumor arising from the anterior cranial fossa. , 2004, Skull base : official journal of North American Skull Base Society ... [et al.].

[6]  G. Har-el.  Anterior Craniofacial Resection Without Facial Skin Incisions-a Review , 2004, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[7]  S. Schmid,et al.  Solitary fibrous tumor of the orbit—two cases and a review of the literature , 2005, European Archives of Oto-Rhino-Laryngology and Head & Neck.

[8]  V. Schramm,et al.  Craniofacial surgery for malignant skull base tumors , 2003, Cancer.

[9]  Y. Shnayder,et al.  Malignant solitary fibrous tumor of the tongue. , 2003, American journal of otolaryngology.

[10]  J. Mullol,et al.  Solitary Fibrous Tumour of the Nasal Cavity and Paranasal Sinuses , 2003, Acta oto-laryngologica.

[11]  R. Yeatts,et al.  Orbital solitary fibrous tumor: radiographic and histopathologic correlations. , 2001, Ophthalmic plastic and reconstructive surgery.

[12]  H. Hashimoto,et al.  Extrapleural solitary fibrous tumor: clinicopathologic study of 17 cases and molecular analysis of the p53 pathway , 2000, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[13]  S. Hirohashi,et al.  Extrathoracic solitary fibrous tumors: their histological variability and potentially aggressive behavior. , 1999, Human pathology.

[14]  S. Segal,et al.  Solitary fibrous tumor of the nasal cavity , 1999, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[15]  N. Ordóñez,et al.  Extrapleural solitary fibrous tumor: a clinicopathologic study of 24 cases. , 1999, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[16]  G. Har-el.  Medial maxillectomy via midfacial degloving approach , 1999 .

[17]  Y. Hasegawa,et al.  Solitary fibrous tumor of the paranasal sinuses , 1999, European Archives of Oto-Rhino-Laryngology.

[18]  S. Dry,et al.  Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intra-thoracic tumors. , 1998, The American journal of surgical pathology.

[19]  H. Kfoury,et al.  Solitary Fibrous Tumor of the Parapharyngeal Space: A Case Report and Review of the Literature , 1996, Ear, nose, & throat journal.

[20]  D. Ross,et al.  Solitary fibrous tumor of the paranasal sinuses: CT and MR appearance. , 1996, AJNR. American journal of neuroradiology.

[21]  C. Létoublon,et al.  Solitary fibrous tumour of the liver with CD34 expression , 1996, Histopathology.

[22]  M. Miettinen,et al.  Solitary fibrous tumor: histological and immunohistochemical spectrum of benign and malignant variants presenting at different sites. , 1995, Human pathology.

[23]  W. Gerald,et al.  Solitary Fibrous Tumor Consistent CD34 Immunoreactivity and Occurrence in the Orbit , 1994, The American journal of surgical pathology.

[24]  G. Witkin,et al.  Solitary Fibrous Tumor of the Upper Respiratory Tract: A Report of Six Cases , 1991, The American journal of surgical pathology.

[25]  A. Rosenberg,et al.  Solitary Fibrous Tumor of the Nasal Cavity and Paranasal Sinuses , 1991, The American journal of surgical pathology.

[26]  L. Hochholzer,et al.  Localized Benign and Malignant Fibrous Tumors of the Pleura: A Clinicopathologic Review of 223 Cases , 1989, The American journal of surgical pathology.

[27]  A. Fam,et al.  Gonococcal arthritis: a report of six cases. , 1973, Canadian Medical Association journal.

[28]  J. Lemercier,et al.  [PRIMARY NEOPLASMS OF THE PLEURA]. , 1963, Gazette medicale de France.