(UPR). Endoplasmic reticulum chaperone BiP (GRP78) is a central regulator for ERS as it is able to control the activa‐ tion of transmembrane ERS sensors, serine/threonine‐protein kinase/endoribonuclease IRE1, eukaryotic translation initiation factor 2‐alpha kinase 3 and cyclic AMP‐dependent transcri