Isolated right atrium tuberculoma causing complete heart block

Myocardial tuberculosis was rare even in the era before effective anti-tuberculous chemotherapy was available. It is becoming even rarer with improved anti-tuberculous treatment. It was usually an incidental finding during necropsy. In a case series reported by Custer and Charr,1 they reviewed more than 14 000 deaths due to tuberculosis and found only 64 cases (0.5%) of tuberculosis involving the heart. In most cases the infection is either part of miliary tuberculosis or an extension of pericardial involvement. In the absence of these, it is presumed to be due to haematogenous or lymphatic dissemination.2 There is almost always a tuberculous focus elsewhere in the body; single isolated tuberculoma are very rare indeed. Complete heart block as a complication of myocardial tuberculosis has been described only rarely in medical literature. Thus far, only a limited number of cases have been reported,3–7 and none of these was due to a tuberculoma in the right atrium. A 35-year-old immunocompromised man was admitted with progressively worsening heart failure of 1-month duration. He had been diagnosed 3 months previously as having HIV and hepatitis C infection, but had defaulted on follow-up since then. History of note includes poor appetite, weight loss and intermittent low-grade fever for 1 week before admission. There was progressive worsening of pedal oedema and reduced effort tolerance during this period. He was an active intravenous drug user, but claimed that he had quit a year ago. He denied any syncope or loss of consciousness. He had previously been well and denied any history of contact with tuberculosis. …

[1]  A. Anwar,et al.  Bicaval obstruction complicating right atrial tuberculoma:the diagnostic value of Cardiovascular MR , 2008, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[2]  P. Vaideeswar,et al.  Tuberculoma of the heart. , 2006, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[3]  H. Rickli,et al.  Fever and night sweats in a 22-year-old man with a mediastinal mass involving the heart. , 2003, Chest.

[4]  A. Gupta,et al.  A rare site for tuberculosis. , 2002, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[5]  M. Halim,et al.  Myocardial tuberculoma with rupture and pseudoaneurysm formation--successful surgical treatment. , 1985, British heart journal.

[6]  D. Human,et al.  Tuberculous aneurysm of the left ventricle. A case report. , 1983, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[7]  C. Wren,et al.  Isolated interventricular septal tuberculoma causing complete heart block. , 1982, Thorax.

[8]  M. Redonnet,et al.  Tuberculous aortic insufficiency. Report of a case with successful surgical treatment. , 1981, The Journal of thoracic and cardiovascular surgery.

[9]  T. Shikata,et al.  Report of Nine Cases , 1979 .

[10]  R. Grolleau,et al.  [Complete atrio-ventricular block caused by tuberculoma of the inter-atrial septum. Histological analysis]. , 1975, Archives des maladies du coeur et des vaisseaux.

[11]  M. M. Rananaware,et al.  Tuberculoma of the heart. Report of 9 cases. , 1973, American heart journal.

[12]  Kinare Sg,et al.  Complete atrioventricular block due to myocardial tuberculosis. Report of a case. , 1969, Archives of pathology.

[13]  E. Chesler,et al.  Tuberculous aneurysm of the left ventricle. , 1969, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[14]  W. Parafiniuk [Tuberculosis of the myocardium]. , 1968, Gruzlica i choroby pluc; tuberculosis et pneumonologia.

[15]  R. Schlant,et al.  Right ventricular outflow tract obstruction produced by a myocardial abscess in a patient with tuberculosis. , 1968, The American journal of cardiology.

[16]  A. Pomerance TUBERCULOMA OF THE INTERVENTRICULAR SEPTUM , 1963, British heart journal.

[17]  I. Rose Tuberculosis of the myocardium report of a case exhibiting changing types of heart block. , 1952, American review of tuberculosis.

[18]  T. B. Menon,et al.  Tuberculosis of the Myocardium Causing Complete Heart Block. , 1945, The American journal of pathology.