The hematopoietic transcription factor PU.1 regulates RANK gene expression in myeloid progenitors.

[1]  Michael C. Ostrowski,et al.  Microphthalmia Transcription Factor and PU.1 Synergistically Induce the Leukocyte Receptor Osteoclast-associated Receptor Gene Expression* , 2003, Journal of Biological Chemistry.

[2]  Toshio Matsumoto,et al.  Expression of RANK is dependent upon differentiation into the macrophage/osteoclast lineage: induction by 1alpha,25-dihydroxyvitamin D3 and TPA in a human myelomonocytic cell line, HL60. , 2003, Bone.

[3]  David L. Lacey,et al.  Osteoclast differentiation and activation , 2003, Nature.

[4]  John Anastasi,et al.  Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. , 2002, Immunity.

[5]  G. Karsenty,et al.  Transcription factors in bone: developmental and pathological aspects. , 2002, Trends in molecular medicine.

[6]  Michael C. Ostrowski,et al.  Microphthalmia Transcription Factor Is a Target of the p38 MAPK Pathway in Response to Receptor Activator of NF-κB Ligand Signaling* , 2002, The Journal of Biological Chemistry.

[7]  Hyun-Jun Lee,et al.  PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. , 2002, Immunity.

[8]  Ellen V Rothenberg,et al.  Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage. , 2002, Immunity.

[9]  D. Fisher,et al.  Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice. , 2001, Molecular cell.

[10]  Michael C. Ostrowski,et al.  Genetic and Physical Interactions betweenMicrophthalmia Transcription Factor and PU.1 Are Necessary for Osteoclast Gene Expression and Differentiation* , 2001, The Journal of Biological Chemistry.

[11]  D. Fisher,et al.  Linking osteopetrosis and pycnodysostosis: Regulation of cathepsin K expression by the microphthalmia transcription factor family , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[12]  T. Kitamura,et al.  Plat-E: an efficient and stable system for transient packaging of retroviruses , 2000, Gene Therapy.

[13]  D L Lacey,et al.  RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[14]  T. Miyata,et al.  Commitment and Differentiation of Osteoclast Precursor Cells by the Sequential Expression of C-Fms and Receptor Activator of Nuclear Factor κb (Rank) Receptors , 1999, The Journal of experimental medicine.

[15]  W. Dougall,et al.  RANK is essential for osteoclast and lymph node development. , 1999, Genes & development.

[16]  R. Steinman,et al.  TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells. , 1999, Journal of immunology.

[17]  Y. Oike,et al.  Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation. , 1999, The American journal of pathology.

[18]  T. Martin,et al.  A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. , 1998, Endocrinology.

[19]  J. Walsh,et al.  PU.1 regulates both cytokine‐dependent proliferation and differentiation of granulocyte/macrophage progenitors , 1998, The EMBO journal.

[20]  R. Dubose,et al.  A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function , 1997, Nature.

[21]  S. Mckercher,et al.  Osteopetrosis in mice lacking haematopoietic transcription factor PU.1 , 1997, Nature.

[22]  A. Brass,et al.  Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1. , 1996, Genes & development.

[23]  J. Kehrl,et al.  Analysis of the Bruton's tyrosine kinase gene promoter reveals critical PU.1 and SP1 sites. , 1996, Blood.

[24]  L. Zon,et al.  Developmental biology of hematopoiesis. , 1995, Blood.

[25]  K. Arai,et al.  Definition of cis-Regulatory Elements of the Mouse Interleukin-5 Gene Promoter , 1995, The Journal of Biological Chemistry.

[26]  James A. Vaught,et al.  microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. , 1994, Genes & development.

[27]  E. Scott,et al.  Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. , 1994, Science.

[28]  T. Hawley,et al.  Versatile retroviral vectors for potential use in gene therapy. , 1994, Gene therapy.

[29]  D. Tenen,et al.  The Sp1 transcription factor binds the CD11b promoter specifically in myeloid cells in vivo and is essential for myeloid-specific promoter activity. , 1993, The Journal of biological chemistry.

[30]  D. Tenen,et al.  The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor , 1993, Molecular and cellular biology.

[31]  M. Cecchini,et al.  Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. , 1990, Endocrinology.

[32]  S. Nishikawa,et al.  The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene , 1990, Nature.

[33]  J. Penninger,et al.  RANK-L and RANK: T cells, bone loss, and mammalian evolution. , 2002, Annual review of immunology.

[34]  H. Singh,et al.  PU.1, a shared transcriptional regulator of lymphoid and myeloid cell fates. , 1999, Cold Spring Harbor symposia on quantitative biology.