IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer
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George Poulogiannis | Paul H Dear | S. Mulholland | P. Dear | M. Arends | G. Poulogiannis | A. Ibrahim | Frank McCaughan | Mark J Arends | Elizabeth Day | Shani Mulholland | Ashraf E K Ibrahim | F. McCaughan | E. Day
[1] Adrian V. Lee,et al. Mammary Tumorigenesis and Metastasis Caused by Overexpression of Insulin Receptor Substrate 1 (IRS-1) or IRS-2 , 2006, Molecular and Cellular Biology.
[2] L. Shaw,et al. Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion. , 2009, Cancer research.
[3] Steven J. M. Jones,et al. Comprehensive molecular characterization of human colon and rectal cancer , 2012, Nature.
[4] S. Leung,et al. Prognostic relevance of DNA copy number changes in colorectal cancer , 2010, The Journal of pathology.
[5] L. Shaw,et al. Divergent Roles for IRS-1 and IRS-2 in Breast Cancer Metastasis , 2007, Cell cycle.
[6] L. Chin,et al. High-resolution genomic profiles of human lung cancer. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[7] D. Yee,et al. Motility Response to Insulin-like Growth Factor-I (IGF-I) in MCF-7 Cells is Associated with IRS-2 Activation and Integrin Expression , 2004, Breast Cancer Research and Treatment.
[8] D. Arlt,et al. Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells , 2000, Molecular and Cellular Endocrinology.
[9] Adrian V. Lee,et al. Oncogenic Transformation by the Signaling Adaptor Proteins Insulin Receptor Substrate (IRS)-1 and IRS-2 , 2007, Cell cycle.
[10] A. Hsieh,et al. Oncogenic AKTivation of translation as a therapeutic target , 2011, British Journal of Cancer.
[11] L. Chin,et al. Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types. , 2007, Cancer research.
[12] K. Kinzler,et al. Genetic instabilities in human cancers , 1998, Nature.
[13] G. Stamp,et al. Validation of a model of colon cancer progression , 2000, The Journal of pathology.
[14] B. Leggett,et al. DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer? , 1999, Journal of clinical pathology.
[15] D. Yee,et al. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines , 2001, Oncogene.
[16] H. Morreau,et al. Single nucleotide polymorphism array analysis of chromosomal instability patterns discriminates rectal adenomas from carcinomas , 2007, The Journal of pathology.
[17] G. Cavet,et al. Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer , 2009, Molecular Cancer Therapeutics.
[18] Derek Y. Chiang,et al. The landscape of somatic copy-number alteration across human cancers , 2010, Nature.
[19] J. Kushner,et al. Irs2 inactivation suppresses tumor progression in Pten+/- mice. , 2009, The American journal of pathology.
[20] Krzysztof Goryca,et al. Modeling Oncogenic Signaling in Colon Tumors by Multidirectional Analyses of Microarray Data Directed for Maximization of Analytical Reliability , 2010, PloS one.
[21] L. Shaw,et al. Expression and function of the insulin receptor substrate proteins in cancer , 2009, Cell Communication and Signaling.
[22] T. Rabbitts,et al. Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer. , 2010, American journal of respiratory and critical care medicine.
[23] A. Sparks,et al. The Genomic Landscapes of Human Breast and Colorectal Cancers , 2007, Science.
[24] R. Broaddus,et al. Loss of Inhibitory Insulin Receptor Substrate-1 Phosphorylation Is an Early Event in Mammalian Target of Rapamycin–Dependent Endometrial Hyperplasia and Carcinoma , 2010, Cancer Prevention Research.
[25] Jude Kendall,et al. Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer , 2007, Proceedings of the National Academy of Sciences.
[26] S. Byron,et al. Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells , 2006, British Journal of Cancer.
[27] Á. Csiszár. Structural and functional diversity of adaptor proteins involved in tyrosine kinase signalling. , 2006, BioEssays : news and reviews in molecular, cellular and developmental biology.
[28] Cathie Garnis,et al. Genetic alteration and gene expression modulation during cancer progression , 2004, Molecular Cancer.
[29] L. Cantley,et al. PI3K pathway alterations in cancer: variations on a theme , 2008, Oncogene.
[30] Thomas Downey,et al. A ‘metastasis-prone’ signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics , 2010, Clinical & Experimental Metastasis.
[31] T. Yeatman,et al. Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer , 2007, Genome Biology.
[32] J. Jass. Hyperplastic-like polyps as precursors of microsatellite-unstable colorectal cancer. , 2003, American journal of clinical pathology.
[33] P. Gassmann,et al. Organ-specific metastatic tumor cell adhesion and extravasation of colon carcinoma cells with different metastatic potential. , 2006, The American journal of pathology.
[34] D. Yee,et al. Multiple Signaling Pathways are Activated During Insulin-like Growth Factor-I (IGF-I) Stimulated Breast Cancer Cell Migration , 2005, Breast Cancer Research and Treatment.
[35] S. Tavaré,et al. Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression , 2010, Gut.
[36] G. Parmigiani,et al. Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers , 2008, Proceedings of the National Academy of Sciences.
[37] T. Rabbitts,et al. Interrogation of genomes by molecular copy-number counting (MCC) , 2006, Nature Methods.
[38] D. Hanahan,et al. The Hallmarks of Cancer , 2000, Cell.
[39] L. Chin,et al. Making sense of cancer genomic data. , 2011, Genes & development.
[40] F. Bertucci,et al. Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters , 2004, Oncogene.
[41] P. Nowell. The clonal evolution of tumor cell populations. , 1976, Science.
[42] P. George,et al. Microdissection molecular copy‐number counting (µMCC)—unlocking cancer archives with digital PCR , 2008, The Journal of pathology.
[43] J. Ptak,et al. Colorectal cancer: Mutations in a signalling pathway , 2005, Nature.
[44] D. Adams,et al. PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice , 2010, Proceedings of the National Academy of Sciences.
[45] M. Stratton,et al. The cancer genome , 2009, Nature.