Negative Regulators of Inflammation as Endogenous Protective Mechanisms in Postinfarction Remodeling

[1]  N. Frangogiannis Matricellular proteins in cardiac adaptation and disease. , 2012, Physiological reviews.

[2]  Y. Okada,et al.  Regulatory Role of Dendritic Cells in Postinfarction Healing and Left Ventricular Remodeling , 2012, Circulation.

[3]  N. Frangogiannis,et al.  Regulation of the inflammatory response in cardiac repair. , 2012, Circulation research.

[4]  N. Voelkel,et al.  The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse , 2011, Proceedings of the National Academy of Sciences.

[5]  A. Devitt,et al.  The innate immune system and the clearance of apoptotic cells , 2011, Journal of leukocyte biology.

[6]  S. Butz,et al.  GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice , 2011, Nature Medicine.

[7]  Garret A. FitzGerald,et al.  Prostaglandins and Inflammation , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[8]  D. Mann The emerging role of innate immunity in the heart and vascular system: for whom the cell tolls. , 2011, Circulation research.

[9]  P. Proost,et al.  Effect of posttranslational processing on the in vitro and in vivo activity of chemokines. , 2011, Experimental cell research.

[10]  T. Noda,et al.  Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury , 2011, Circulation.

[11]  A. Bowie,et al.  The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling. , 2010, Biochemical pharmacology.

[12]  A. Thiel,et al.  Identification of Noncytotoxic and IL-10–Producing CD8+AT2R+ T Cell Population in Response to Ischemic Heart Injury , 2010, The Journal of Immunology.

[13]  C. Serhan Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not? , 2010, The American journal of pathology.

[14]  Xiao-Fan Wang,et al.  Smad3 Signaling Critically Regulates Fibroblast Phenotype and Function in Healing Myocardial Infarction , 2010, Circulation research.

[15]  Yu Lin,et al.  Resolvin E1 protects the rat heart against reperfusion injury. , 2010, American journal of physiology. Heart and circulatory physiology.

[16]  O. Soehnlein,et al.  Phagocyte partnership during the onset and resolution of inflammation , 2010, Nature Reviews Immunology.

[17]  G. Biondi-Zoccai,et al.  Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). , 2010, The American journal of cardiology.

[18]  N. Frangogiannis,et al.  Cardiovascular , Pulmonary and Renal Pathology CCR 5 Signaling Suppresses Inflammation and Reduces Adverse Remodeling of the Infarcted Heart , Mediating Recruitment of Regulatory T Cells , 2010 .

[19]  Clinton S. Robbins,et al.  The multiple roles of monocyte subsets in steady state and inflammation , 2010, Cellular and Molecular Life Sciences.

[20]  S. Akira,et al.  The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors , 2010, Nature Immunology.

[21]  Dan R. Littman,et al.  Th17 and Regulatory T Cells in Mediating and Restraining Inflammation , 2010, Cell.

[22]  N. Frangogiannis,et al.  The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. , 2010, Journal of molecular and cellular cardiology.

[23]  P. Doevendans,et al.  Myocardial Ischemia / Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti – Toll-Like Receptor-2 Antibody , 2009 .

[24]  Steven L. Kunkel,et al.  Critical Role of IL-1 Receptor-Associated Kinase-M in Regulating Chemokine-Dependent Deleterious Inflammation in Murine Influenza Pneumonia , 2009, The Journal of Immunology.

[25]  Stephanie L. K. Bowers,et al.  Cardiac Fibroblast: The Renaissance Cell , 2009, Circulation research.

[26]  T. Akasaka,et al.  Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. , 2009, Journal of the American College of Cardiology.

[27]  N. Frangogiannis The immune system and cardiac repair. , 2008, Pharmacological research.

[28]  L. O’Neill When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction. , 2008, Immunity.

[29]  K. Chatila,et al.  Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. , 2008, The American journal of pathology.

[30]  B. Funke,et al.  High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart , 2008, Circulation.

[31]  C. Tschöpe,et al.  Toll-Like Receptor-4 Modulates Survival by Induction of Left Ventricular Remodeling after Myocardial Infarction in Mice1 , 2008, The Journal of Immunology.

[32]  Richard A Flavell,et al.  Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10. , 2008, Immunity.

[33]  P. Libby,et al.  The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions , 2007, The Journal of experimental medicine.

[34]  Guofeng Ren,et al.  Essential Role of Smad3 in Infarct Healing and in the Pathogenesis of Cardiac Remodeling , 2007, Circulation.

[35]  R. Vasan,et al.  Heart failure in the twenty-first century: is it a coronary artery disease or hypertension problem? , 2007, Cardiology clinics.

[36]  M. Entman,et al.  Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. , 2007, Cardiovascular research.

[37]  N. Frangogiannis Chemokines in ischemia and reperfusion , 2007, Thrombosis and Haemostasis.

[38]  N. Frangogiannis,et al.  The role of TGF-β Signaling in Myocardial Infarction and Cardiac Remodeling , 2007 .

[39]  De-Pei Liu,et al.  Targeted Cardiac Overexpression of A20 Improves Left Ventricular Performance and Reduces Compensatory Hypertrophy After Myocardial Infarction , 2007, Circulation.

[40]  Ajai Kumar Jain,et al.  PexeLizumab for Acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: A randomized controlled trial , 2007 .

[41]  M. Entman,et al.  The role of platelet-derived growth factor signaling in healing myocardial infarcts. , 2006, Journal of the American College of Cardiology.

[42]  Alberto Mantovani,et al.  Tuning inflammation and immunity by chemokine sequestration: decoys and more , 2006, Nature Reviews Immunology.

[43]  K. Sunagawa,et al.  Tumor Necrosis Factor is Toxic Via Receptor 1 and Protective Via Receptor 2 in a Murine Model of Myocardial Infarction , 2006 .

[44]  H. Drexler,et al.  The Transforming Growth Factor-&bgr; Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury , 2006 .

[45]  W. Burns,et al.  Connective Tissue Growth Factor and Cardiac Fibrosis after Myocardial Infarction , 2005, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[46]  M. Entman,et al.  Critical Role of Endogenous Thrombospondin-1 in Preventing Expansion of Healing Myocardial Infarcts , 2005, Circulation.

[47]  G. Takemura,et al.  Postinfarction Gene Therapy Against Transforming Growth Factor-β Signal Modulates Infarct Tissue Dynamics and Attenuates Left Ventricular Remodeling and Heart Failure , 2005 .

[48]  B. Rollins,et al.  CCL2/Monocyte Chemoattractant Protein-1 Regulates Inflammatory Responses Critical to Healing Myocardial Infarcts , 2005, Circulation research.

[49]  A. Mauviel Transforming Growth Factor-β , 2005 .

[50]  A. Yoshimura,et al.  Negative regulation of cytokine and TLR signalings by SOCS and others. , 2005, Advances in immunology.

[51]  Hiroyuki Tsutsui,et al.  Inhibition of TGF-beta signaling exacerbates early cardiac dysfunction but prevents late remodeling after infarction. , 2004, Cardiovascular research.

[52]  I. Dixon,et al.  Excessive Tumor Necrosis Factor Activation After Infarction Contributes to Susceptibility of Myocardial Rupture and Left Ventricular Dysfunction , 2004, Circulation.

[53]  A. Mauviel,et al.  TGF-β-induced SMAD signaling and gene regulation : consequences for extracellular matrix remodeling and wound healing , 2004 .

[54]  Shizuo Akira,et al.  Toll-like receptor signalling , 2004, Nature Reviews Immunology.

[55]  F. Martinon,et al.  RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation , 2004, Nature Immunology.

[56]  M. Entman,et al.  Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction. , 2004, The American journal of pathology.

[57]  J. Oyama,et al.  Reduced Myocardial Ischemia-Reperfusion Injury in Toll-Like Receptor 4-Deficient Mice , 2003, Circulation.

[58]  M. Pfeffer,et al.  Predictors of late development of heart failure in stable survivors of myocardial infarction: the CARE study. , 2003, Journal of the American College of Cardiology.

[59]  Y. Ahn,et al.  A20 Is Dynamically Regulated in the Heart and Inhibits the Hypertrophic Response , 2003, Circulation.

[60]  M. Entman,et al.  MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype. , 2003, American journal of physiology. Heart and circulatory physiology.

[61]  Steffen Jung,et al.  Blood monocytes consist of two principal subsets with distinct migratory properties. , 2003, Immunity.

[62]  K. Burns,et al.  Inhibition of Interleukin 1 Receptor/Toll-like Receptor Signaling through the Alternatively Spliced, Short Form of MyD88 Is Due to Its Failure to Recruit IRAK-4 , 2003, The Journal of experimental medicine.

[63]  R. Gibbons,et al.  The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: the results of the HALT-MI study. , 2002, Journal of the American College of Cardiology.

[64]  E. Puré,et al.  Resolution of Lung Inflammation by CD44 , 2002, Science.

[65]  M. Entman,et al.  Morphological Characteristics of the Microvasculature in Healing Myocardial Infarcts , 2002, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[66]  V. Fadok,et al.  Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. , 2002, The Journal of clinical investigation.

[67]  Y. Kaneda,et al.  Overexpression of Interleukin-1 Receptor Antagonist Provides Cardioprotection Against Ischemia-Reperfusion Injury Associated With Reduction in Apoptosis , 2001, Circulation.

[68]  P. Tsao,et al.  Stent-Based Delivery of Sirolimus Reduces Neointimal Formation in a Porcine Coronary Model , 2001, Circulation.

[69]  M. Entman,et al.  Induction and suppression of interferon‐inducible protein (IP)‐10 in reperfused myocardial infarcts may regulate angiogenesis , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[70]  Z. Ding,et al.  Leukocyte trafficking and myocardial reperfusion injury in ICAM-1/P-selectin-knockout mice. , 2001, American journal of physiology. Heart and circulatory physiology.

[71]  Merry L. Lindsey,et al.  IL-10 Is Induced in the Reperfused Myocardium and May Modulate the Reaction to Injury1 , 2000, The Journal of Immunology.

[72]  G Baumgarten,et al.  Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[73]  Z. Yang,et al.  Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury. , 2000, Circulation.

[74]  M. Lindsey,et al.  Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion. , 1998, Circulation.

[75]  D. Baltimore,et al.  NF-κB Activation: The IκB Kinase Revealed? , 1997, Cell.

[76]  M. Kitamura,et al.  Identification of an inhibitor targeting macrophage production of monocyte chemoattractant protein-1 as TGF-beta 1. , 1997, Journal of immunology.

[77]  L. Brown,et al.  VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis. , 1996, The American journal of physiology.

[78]  A. Desmoulière,et al.  Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts , 1993, The Journal of cell biology.

[79]  A. A. Taylor,et al.  Inflammation in the course of early myocardial ischemia , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[80]  D. Baltimore,et al.  NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control , 1989, Cell.

[81]  M. Entman,et al.  Mechanism of Complement Activation After Coronary Artery Occlusion: Evidence That Myocardial Ischemia in Dogs Causes Release of Constituents of Myocardial Subcellular Origin That Complex With Human C1q In Vivo , 1988, Circulation research.

[82]  M. Sporn,et al.  Transforming growth factor beta-1 in acute myocardial infarction in rats. , 1988, Growth factors.

[83]  R M Whitlock,et al.  Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. , 1987, Circulation.