Macrophage Inflammatory Protein‐1α Induces Hypercalcemia in Adult T‐Cell Leukemia

Hypercalcemia is observed in >80% of ATL. Serum MIP‐1α levels were elevated in all 24 ATL with hypercalcemia but undetectable in all 10 patients with humoral hypercalcemia of malignancy with solid tumors and in 34 of 37 ATL without hypercalcemia. We propose that serum MIP‐1α is a clinical hallmark for hypercalcemia in ATL.

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