Phenotyping of sensory and sympathetic ganglion neurons of a galanin-overexpressing mouse—Possible implications for pain processing

[1]  T. Hökfelt,et al.  Galanin receptor 1 is expressed in a subpopulation of glutamatergic interneurons in the dorsal horn of the rat spinal cord , 2006, The Journal of comparative neurology.

[2]  T. Hökfelt,et al.  Differential distribution and regulation of galanin receptors- 1 and -2 in the rat lumbar spinal cord , 2006, Brain Research.

[3]  J. Hohmann,et al.  Ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice , 2005, Neuroscience.

[4]  T. Hökfelt,et al.  Generation and phenotypic characterization of a galanin overexpressing mouse , 2005, Neuroscience.

[5]  T. Hökfelt,et al.  Galanin and spinal nociceptive mechanisms: Recent results from transgenic and knock-out models , 2005, Neuropeptides.

[6]  I. Kondo,et al.  Mechanisms of antinociception of spinal galanin: how does galanin inhibit spinal sensitization? , 2005, Neuropeptides.

[7]  D. Wynick,et al.  Use of genetically engineered transgenic mice to investigate the role of galanin in the peripheral nervous system after injury , 2005, Neuropeptides.

[8]  Long-chuan Yu,et al.  Interactions of galanin and opioids in nociceptive modulation in the arcuate nucleus of hypothalamus in rats , 2005, Regulatory Peptides.

[9]  John K. Robinson Galanin and cognition. , 2004, Behavioral and cognitive neuroscience reviews.

[10]  T. Hökfelt,et al.  Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injury , 2004, Brain Research.

[11]  Long-chuan Yu,et al.  Antinociceptive effects of galanin in the rat tuberomammillary nucleus and the plasticity of galanin receptor 1 during hyperalgesia , 2004, Journal of neuroscience research.

[12]  A. Todd,et al.  Peripheral axotomy induces depletion of the vesicular glutamate transporter VGLUT1 in central terminals of myelinated afferent fibres in the rat spinal cord , 2004, Brain Research.

[13]  R. Villalba,et al.  Vesicular glutamate transporters in the spinal cord, with special reference to sensory primary afferent synapses , 2004, The Journal of comparative neurology.

[14]  F. Fujiyama,et al.  Independent inputs by VGLUT2- and VGLUT3-positive glutamatergic terminals onto rat sympathetic preganglionic neurons , 2004, Neuroreport.

[15]  T. Bártfai,et al.  Galanin Acts at GalR1 Receptors in Spinal Antinociception: Synergy with Morphine and AP-5 , 2004, Journal of Pharmacology and Experimental Therapeutics.

[16]  F. Nagy,et al.  Expression of vesicular glutamate transporters in rat lumbar spinal cord, with a note on dorsal root ganglia , 2004, The Journal of comparative neurology.

[17]  T. Hökfelt,et al.  Galanin increases membrane excitability and enhances Ca2+ currents in adult, acutely dissociated dorsal root ganglion neurons , 2003, The European journal of neuroscience.

[18]  A. Craig,et al.  Pain mechanisms: labeled lines versus convergence in central processing. , 2003, Annual review of neuroscience.

[19]  Takeshi Kaneko,et al.  Cellular localization of three vesicular glutamate transporter mRNAs and proteins in rat spinal cord and dorsal root ganglia , 2003, Synapse.

[20]  Long-chuan Yu,et al.  An antinociceptive role of galanin in the arcuate nucleus of hypothalamus in intact rats and rats with inflammation , 2003, Pain.

[21]  F. Fujiyama,et al.  Vesicular glutamate transporters, VGluT1 and VGluT2, in the trigeminal ganglion neurons of the rat, with special reference to coexpression , 2003, The Journal of comparative neurology.

[22]  Masahiko Watanabe,et al.  Subtype switching of vesicular glutamate transporters at parallel fibre–Purkinje cell synapses in developing mouse cerebellum , 2003, The European journal of neuroscience.

[23]  E. Mufson,et al.  Galanin in Alzheimer disease. , 2003, Molecular interventions.

[24]  J. Crawley,et al.  Reduced spinal cord sensitization to C‐fibre stimulation in mice over‐expressing galanin , 2003, The European journal of neuroscience.

[25]  V. Pachnis,et al.  Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[26]  J. Hohmann,et al.  Distribution and regulation of galanin receptor 1 messenger RNA in the forebrain of wild type and galanin-transgenic mice , 2003, Neuroscience.

[27]  J. Crawley,et al.  Hyperalgesia and increased neuropathic pain-like response in mice lacking galanin receptor 1 receptors , 2003, Neuroscience.

[28]  F. Fujiyama,et al.  Expression of vesicular glutamate transporters, VGluT1 and VGluT2, in axon terminals of nociceptive primary afferent fibers in the superficial layers of the medullary and spinal dorsal horns of the rat , 2003, The Journal of comparative neurology.

[29]  A. Dickenson,et al.  In vivo and in vitro effects of peripheral galanin on nociceptive transmission in naive and neuropathic states , 2003, Neuroscience.

[30]  J. Shine,et al.  The Second Galanin Receptor GalR2 Plays a Key Role in Neurite Outgrowth from Adult Sensory Neurons , 2003, The Journal of Neuroscience.

[31]  G. G. Nagy,et al.  The expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in neurochemically defined axonal populations in the rat spinal cord with emphasis on the dorsal horn , 2003, The European journal of neuroscience.

[32]  J. Crawley,et al.  Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance , 2002, Neuropeptides.

[33]  M. Vrontakis Galanin: a biologically active peptide. , 2002, Current drug targets. CNS and neurological disorders.

[34]  T. Hökfelt,et al.  The participation of galanin in pain processing at the spinal level. , 2002, Trends in pharmacological sciences.

[35]  A. Dickenson,et al.  Nerve injury induces plasticity that results in spinal inhibitory effects of galanin , 2002, Pain.

[36]  T. Hökfelt,et al.  Galanin overexpressing transgenic mice , 2002, Neuropeptides.

[37]  D. Wynick,et al.  Targeted disruption of galanin: new insights from knock-out studies , 2002, Neuropeptides.

[38]  S. Waxman,et al.  Flanking regulatory sequences of the locus encoding the murine GDNF receptor, c‐ret, directs lac Z (β‐galactosidase) expression in developing somatosensory system , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[39]  Xiao-jun Xu,et al.  Neuropeptides in neuropathic and inflammatory pain with special emphasis on cholecystokinin and galanin. , 2001, European journal of pharmacology.

[40]  T. Hökfelt,et al.  Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: Selective actions via GalR1 and GalR2 receptors , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[41]  J. Hohmann,et al.  Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[42]  T. Hökfelt,et al.  Mice over-expressing galanin have elevated heat nociceptive threshold , 2001, Neuroreport.

[43]  S. McMahon,et al.  The role of galanin as a multi-functional neuropeptide in the nervous system. , 2001, Current opinion in pharmacology.

[44]  J. Schouenborg,et al.  Functional connections are established in the deafferented rat spinal cord by peripherally transplanted human embryonic sensory neurons , 2000, The European journal of neuroscience.

[45]  J. Hohmann,et al.  Modulation of Hippocampal Excitability and Seizures by Galanin , 2022 .

[46]  T. Hökfelt,et al.  Galanin and spinal nociceptive mechanisms: recent advances and therapeutic implications , 2000, Neuropeptides.

[47]  T. Hökfelt,et al.  Effect of Axotomy on Expression of NPY, Galanin, and NPY Y1 and Y2 Receptors in Dorsal Root Ganglia and the Superior Cervical Ganglion Studied with Double-Labeling in Situ Hybridization and Immunohistochemistry , 2000, Experimental Neurology.

[48]  S. McMahon,et al.  Galanin knockout mice reveal nociceptive deficits following peripheral nerve injury , 2000, The European journal of neuroscience.

[49]  T. Lundeberg,et al.  Antinociceptive role of galanin in periaqueductal grey of rats with experimentally induced mononeuropathy , 2000, Neuroscience.

[50]  T. Branchek,et al.  Galanin receptor subtypes. , 2000, Trends in pharmacological sciences.

[51]  T. Hökfelt,et al.  Multiple messengers in descending serotonin neurons: localization and functional implications , 2000, Journal of Chemical Neuroanatomy.

[52]  E. T. O. Rugarn Radioimmunoassay for rat galanin: immunochemical and chromatographic characterization of immunoreactivity in tissue extracts , 2000, Scandinavian journal of clinical and laboratory investigation.

[53]  J. Krause,et al.  Distribution of galanin-1, -2 and -3 receptor messenger RNAs in central and peripheral rat tissues , 1999, Neuroscience.

[54]  C. Wahlestedt,et al.  Expression of the novel galanin receptor subtype GALR2 in the adult rat CNS: Distinct distribution from GALR1 , 1999, The Journal of comparative neurology.

[55]  T. Hökfelt,et al.  Regulation of galanin and neuropeptide Y in dorsal root ganglia and dorsal horn in rat mononeuropathic models: possible relation to tactile hypersensitivity , 1999, Neuroscience.

[56]  JM Besson,et al.  The neurobiology of pain , 1999, The Lancet.

[57]  J. Dostrovsky,et al.  Regulation of Expression of Galanin and Galanin Receptors in Dorsal Root Ganglia and Spinal Cord after Axotomy and Inflammation a , 1998, Annals of the New York Academy of Sciences.

[58]  T. Branchek,et al.  Molecular Biology and Pharmacology of Galanin Receptors , 1998, Annals of the New York Academy of Sciences.

[59]  T. Hökfelt,et al.  Effect of peripheral axotomy on dorsal root ganglion neuron phenotype and autotomy behaviour in neuropeptide Y-deficient mice , 1998, Regulatory Peptides.

[60]  T. Hökfelt,et al.  Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo , 1998, Nature Biotechnology.

[61]  T. Hökfelt,et al.  Expression and regulation of galanin-R2 receptors in rat primary sensory neurons: effect of axotomy and inflammation , 1997, Neuroscience Letters.

[62]  W. Ma,et al.  Differential expression of galanin immunoreactivities in the primary sensory neurons following partial and complete sciatic nerve injuries , 1997, Neuroscience.

[63]  T. Hökfelt,et al.  Evidence for galanin receptors in primary sensory neurones and effect of axotomy and inflammation , 1996, Neuroreport.

[64]  T. Hökfelt,et al.  Influence of leukemia inhibitory factor on galanin/GMAP and neuropeptide Y expression in mouse primary sensory neurons after axotomy , 1996, Experimental Brain Research.

[65]  T. Branchek,et al.  Distribution of a rat galanin receptor mRNA in rat brain , 1996, Neuroreport.

[66]  E. Parker,et al.  Cloning and characterization of the rat GALR1 galanin receptor from Rin14B insulinoma cells. , 1995, Brain research. Molecular brain research.

[67]  J. Crawley Biological actions of galanin , 1995, Regulatory Peptides.

[68]  D. Simmons,et al.  Galanin is contained in GABAergic neurons in the rat spinal dorsal horn , 1995, Neuroscience Letters.

[69]  T. Hökfelt,et al.  Ultrastructural studies on peptides in the dorsal horn of the rat spinal cord—IV. Effects of peripheral axotomy with special reference to neuropeptide Y and vasoactive intestinal polypeptide/peptide histidine isoleucine , 1995, Neuroscience.

[70]  J. Broman,et al.  Evidence for vesicular storage of glutamate in primary afferent terminals. , 1994, NeuroReport.

[71]  R. Weinberg,et al.  Amino acid immunocytochemistry of primary afferent terminals in the rat dorsal horn , 1994, The Journal of comparative neurology.

[72]  R. Nahin,et al.  Primary sensory neurons exhibit altered gene expression in a rat model of neuropathic pain , 1994, Pain.

[73]  E. Mercer,et al.  Cell-specific expression from the human dopamine beta-hydroxylase promoter in transgenic mice is controlled via a combination of positive and negative regulatory elements , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[74]  M. Neilson,et al.  Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[75]  E. Philippe,et al.  Dopamine as trace amine in the dorsal root ganglia , 1993, Neurochemical Research.

[76]  O. Ottersen,et al.  Enrichment of Glutamate‐like Immunoreactivity in Primary Afferent Terminals Throughout the Spinal Cord Dorsal Horn , 1993, The European journal of neuroscience.

[77]  I. Merchenthaler,et al.  Anatomy and physiology of central galanin-containing pathways , 1993, Progress in Neurobiology.

[78]  T. Hökfelt,et al.  CGRP-like immunoreactivity in A11 dopamine neurons projecting to the spinal cord and a note on CGRP-CCK cross-reactivity , 1993, Brain Research.

[79]  Joe C. Adams,et al.  Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains. , 1992, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[80]  T. Hökfelt,et al.  Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistry , 1992, Histochemistry.

[81]  J. Polak,et al.  Ultrastructural visualization of glutamate and aspartate immunoreactivities in the rat dorsal horn, with special reference to the co-localization of glutamate, substance P and calcitonin-gene related peptide , 1991, Neuroscience.

[82]  G. Hoyle,et al.  The dopamine β-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice , 1991, Neuron.

[83]  Z. Wiesenfeld‐Hallin,et al.  Intrathecal galanin blocks the prolonged increase in spinal cord flexor reflex excitability induced by conditioning stimulation of unmyelinated muscle afferents in the rat , 1991, Brain Research.

[84]  A. Rustioni,et al.  Ultrastructural immunocytochemical localization of excitatory amino acids in the somatosensory system. , 1990, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[85]  T. Hökfelt,et al.  On the Role of Galanin, Substance P and Other Neuropeptides in Primary Sensory Neurons of the Rat: Studies on Spinal Reflex Excitability and Peripheral Axotomy , 1990, The European journal of neuroscience.

[86]  T. Hökfelt,et al.  Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galanin , 1989, Neuroscience.

[87]  T. Hökfelt,et al.  The effect of intrathecal galanin on the flexor reflex in rat: Increased depression after sciatic nerve section , 1989, Neuroscience Letters.

[88]  Z. Wiesenfeld‐Hallin,et al.  The effects of intrathecal galanin and C-fiber stimulation on the flexor reflex in the rat , 1989, Brain Research.

[89]  T. Hökfelt,et al.  Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy , 1987, Neuroscience Letters.

[90]  T. Hökfelt,et al.  Distribution of galaninlike immunoreactivity in the rat central nervous system , 1986, The Journal of comparative neurology.

[91]  P. Anand,et al.  Distribution of galanin immunoreactivity in the central nervous system and the responses of galanin-containing neuronal pathways to injury , 1985, Neuroscience.

[92]  D. Jacobowitz,et al.  Galanin-like immunoreactivity in capsaicin sensitive sensory neurons and ganglia , 1985, Brain Research Bulletin.

[93]  T. Hökfelt,et al.  A galanin-like peptide in the central nervous system and intestine of the rat , 1984, Neuroscience Letters.

[94]  A. Mudge,et al.  A subpopulation of rat dorsal root ganglion neurones is catecholaminergic , 1983, Nature.

[95]  J. Haycock,et al.  Activating antibodies to tyrosine hydroxylase. , 1982, The Journal of biological chemistry.

[96]  A. Lundberg,et al.  Reflex pathways from group II muscle afferents , 2004, Experimental Brain Research.

[97]  J. Shine,et al.  Galanin and galanin receptors. , 1999, Results and problems in cell differentiation.

[98]  T. Bartfai,et al.  Galanin--a neuroendocrine peptide. , 1993, Critical reviews in neurobiology.

[99]  F. Amenta,et al.  Presence of catecholamine-related enzymes in a subpopulation of primary sensory neurons in dorsal root ganglia of the rat. , 1991, Cellular and molecular biology.

[100]  Coons Ah Fluorescent antibody methods , 1968 .