Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice

[1]  Helgi B. Schiöth,et al.  Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans , 2012, PLoS genetics.

[2]  M. Missler,et al.  Dendritic spine formation and synaptic function require neurobeachin , 2011, Nature communications.

[3]  A. Beaudet,et al.  Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. , 2011, Human molecular genetics.

[4]  R. D'Hooge,et al.  Nocturnal hyperactivity, increased social novelty preference and delayed extinction of fear responses in post-weaning socially isolated mice , 2011, Brain Research Bulletin.

[5]  J. Silverman,et al.  Automated Three‐Chambered Social Approach Task for Mice , 2011, Current protocols in neuroscience.

[6]  M. Zhuo,et al.  Upregulation of CREB-Mediated Transcription Enhances Both Short- and Long-Term Memory , 2011, The Journal of Neuroscience.

[7]  T. Nickl-Jockschat,et al.  The role of neurotrophic factors in autism , 2011, Molecular Psychiatry.

[8]  J. Creemers,et al.  The autism candidate gene Neurobeachin encodes a scaffolding protein implicated in membrane trafficking and signaling. , 2011, Current molecular medicine.

[9]  C. McDougle,et al.  Structural and functional magnetic resonance imaging of autism spectrum disorders , 2011, Brain Research.

[10]  E. Kandel,et al.  Gene Expression Profiling of Facilitated L-LTP in VP16-CREB Mice Reveals that BDNF Is Critical for the Maintenance of LTP and Its Synaptic Capture , 2011, Neuron.

[11]  H. Trompeter,et al.  Network-like impact of MicroRNAs on neuronal lineage differentiation of unrestricted somatic stem cells from human cord blood. , 2011, Stem cells and development.

[12]  R. D'Hooge,et al.  Impaired appetitively as well as aversively motivated behaviors and learning in PDE10A-deficient mice suggest a role for striatal signaling in evaluative salience attribution , 2011, Neurobiology of Learning and Memory.

[13]  C. Lord,et al.  Behavioural phenotyping assays for mouse models of autism , 2010, Nature Reviews Neuroscience.

[14]  Jurgen Del-Favero,et al.  SCAMP5, NBEA and AMISYN: three candidate genes for autism involved in secretion of large dense-core vesicles. , 2010, Human molecular genetics.

[15]  M. Missler,et al.  Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses , 2009, The Journal of physiology.

[16]  Bruno Poucet,et al.  Impaired long-term stability of CA1 place cell representation in mice lacking the transcription factor zif268/egr1 , 2009, Proceedings of the National Academy of Sciences.

[17]  E. Fombonne Epidemiology of Pervasive Developmental Disorders , 2009, Pediatric Research.

[18]  Isabelle Callebaut,et al.  A concanavalin A-like lectin domain in the CHS1/LYST protein, shared by members of the BEACH family , 2009, Bioinform..

[19]  L. Arckens,et al.  Identification and localization of functional subdivisions in the visual cortex of the adult mouse , 2009, The Journal of comparative neurology.

[20]  A. Morozov,et al.  Enhanced generalization of auditory conditioned fear in juvenile mice. , 2009, Learning & memory.

[21]  E. Kandel,et al.  Chronic enhancement of CREB activity in the hippocampus interferes with the retrieval of spatial information. , 2009, Learning & memory.

[22]  S S Moy,et al.  Social approach in genetically engineered mouse lines relevant to autism , 2009, Genes, brain, and behavior.

[23]  M. Buhot,et al.  Spatial memory in the Morris water maze and activation of cyclic AMP response element-binding (CREB) protein within the mouse hippocampus. , 2008, Learning & memory.

[24]  J. Dodart,et al.  Excitotoxic lesions restricted to the dorsal CA1 field of the hippocampus impair spatial memory and extinction learning in C57BL/6 mice , 2008, Neurobiology of Learning and Memory.

[25]  D. Geschwind,et al.  Advances in autism genetics: on the threshold of a new neurobiology , 2008, Nature Reviews Genetics.

[26]  E. Kandel,et al.  cAMP Response Element-Binding Protein-Mediated Gene Expression Increases the Intrinsic Excitability of CA1 Pyramidal Neurons , 2007, The Journal of Neuroscience.

[27]  S. Dudek,et al.  Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice , 2007, Nature.

[28]  A. Minassian,et al.  Sensorimotor Gating Deficits in Adults with Autism , 2007, Biological Psychiatry.

[29]  R. D'Hooge,et al.  Differences in behavioural test battery performance between mice with hippocampal and cerebellar lesions , 2006, Behavioural Brain Research.

[30]  B. Jenks,et al.  The Effects of Disruption of A Kinase Anchoring Protein–Protein Kinase A Association on Protein Kinase A Signalling in Neuroendocrine Melanotroph Cells of Xenopus laevis , 2006, Journal of neuroendocrinology.

[31]  Patricia A Carpenter,et al.  Verbal and Spatial Working Memory in Autism , 2005, Journal of autism and developmental disorders.

[32]  C. Deutsch,et al.  Macrocephaly and the control of brain growth in autistic disorders , 2005, Progress in Neurobiology.

[33]  Axel T Brunger,et al.  New insights into clostridial neurotoxin-SNARE interactions. , 2005, Trends in molecular medicine.

[34]  R. D'Hooge,et al.  Neurocognitive and Psychotiform Behavioral Alterations and Enhanced Hippocampal Long-Term Potentiation in Transgenic Mice Displaying Neuropathological Features of Human α-Mannosidosis , 2005, The Journal of Neuroscience.

[35]  R. J. McDonald,et al.  Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor‐dependent long‐term potentiation , 2005, The Journal of physiology.

[36]  K. Reddy Cytogenetic abnormalities and fragile-x syndrome in Autism Spectrum Disorder , 2005, BMC Medical Genetics.

[37]  L. Tong,et al.  Crystal structure of the PH-BEACH domains of human LRBA/BGL. , 2004, Biochemistry.

[38]  J. Piven,et al.  Automated apparatus for quantitation of social approach behaviors in mice , 2004, Genes, brain, and behavior.

[39]  J. Golden,et al.  Neurobeachin Is Essential for Neuromuscular Synaptic Transmission , 2004, The Journal of Neuroscience.

[40]  G. B. Schaefer,et al.  Craniofacial and acral growth responses in growth hormone-deficient children treated with growth hormone. , 2004, The Journal of pediatrics.

[41]  T. Laulhere,et al.  Molecular genetic delineation of a deletion of chromosome 13q12→q13 in a patient with autism and auditory processing deficits , 2003, Cytogenetic and Genome Research.

[42]  K. Devriendt,et al.  The neurobeachin gene is disrupted by a translocation in a patient with idiopathic autism , 2003, Journal of medical genetics.

[43]  Alcino J. Silva,et al.  MAPK, CREB and zif268 are all required for the consolidation of recognition memory. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[44]  T. Priestley,et al.  Long-Term Potentiation Is Increased in the CA1 Area of the Hippocampus of APPswe/ind CRND8 Mice , 2002, Neurobiology of Disease.

[45]  L. Tong,et al.  Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain , 2002, The EMBO journal.

[46]  Eric R. Kandel,et al.  Expression of Constitutively Active CREB Protein Facilitates the Late Phase of Long-Term Potentiation by Enhancing Synaptic Capture , 2002, Cell.

[47]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[48]  Barbara L. Hempstead,et al.  Regulation of Cell Survival by Secreted Proneurotrophins , 2001, Science.

[49]  R. D'Hooge,et al.  Applications of the Morris water maze in the study of learning and memory , 2001, Brain Research Reviews.

[50]  George Paxinos,et al.  The Mouse Brain in Stereotaxic Coordinates , 2001 .

[51]  J. D. McGaugh,et al.  Experience-Dependent Gene Expression in the Rat Hippocampus after Spatial Learning: A Comparison of the Immediate-Early GenesArc, c-fos, and zif268 , 2001, The Journal of Neuroscience.

[52]  T. Bliss,et al.  A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories , 2001, Nature Neuroscience.

[53]  R. D'Hooge,et al.  Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice , 2000, Behavioural Brain Research.

[54]  Friedrich W. Herberg,et al.  Neurobeachin: A Protein Kinase A-Anchoring,beige/Chediak-Higashi Protein Homolog Implicated in Neuronal Membrane Traffic , 2000, The Journal of Neuroscience.

[55]  E. Kandel,et al.  Strain-dependent differences in LTP and hippocampus-dependent memory in inbred mice. , 2000, Learning & memory.

[56]  S. T. Warren,et al.  Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function , 1999, Neuroscience.

[57]  D. Linden,et al.  Synaptic Transmission and Hippocampal Long-Term Potentiation in Transgenic Mice Expressing FAD-Linked Presenilin 1 , 1999, Neurobiology of Disease.

[58]  Allan Collins,et al.  Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies , 1997, Psychopharmacology.

[59]  M. Montminy,et al.  Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133 , 1989, Cell.

[60]  Kent C. Berridge,et al.  Progressive degradation of serial grooming chains by descending decerebration , 1989, Behavioural Brain Research.

[61]  E. Ritvo,et al.  Association of autism, retinoblastoma, and reduced esterase D activity. , 1988, Archives of general psychiatry.

[62]  A. L. Goldin,et al.  Neurobiology of Disease , 2014 .

[63]  G. Feng,et al.  Transgenic Mouse Models of Childhood Onset Psychiatric Disorders , 2011 .

[64]  N. Galjart,et al.  Candidate Genes in Ocular Dominance Plasticity , 2012, Front. Neurosci..