The LANSS Pain Scale: the Leeds assessment of neuropathic symptoms and signs

&NA; This study describes the development and validation of a novel tool for identifying patients in whom neuropathic mechanisms dominate their pain experience. The Leeds assessment of neuropathic symptoms and signs (LANSS) Pain Scale is based on analysis of sensory description and bedside examination of sensory dysfunction, and provides immediate information in clinical settings. It was developed in two populations of chronic pain patients. In the first (n=60), the use of sensory descriptors and questions were compared in patients with nociceptive and neuropathic pain, combined with an assessment of sensory function. This data was used to derive a seven item pain scale, consisting of grouped sensory description and sensory examination with a simple scoring system. The LANSS Pain Scale was validated in a second group of patients (n=40) by assessing discriminant ability, internal consistency and agreement by independent raters. Clinical and research applications of the LANSS Pain Scale are discussed.

[1]  J. Atkinson,et al.  Diffusion of pain language with affective disturbance confounds differential diagnosis , 1982, Pain.

[2]  Iasp Subcommittee on Taxonomy.  Classification of chronic pain , 1986 .

[3]  M. Byas-Smith,et al.  Transdermal clonidine compared to placebo in painful diabetic neuropathy using a two-stage ‘enriched enrollment’ design , 1995, Pain.

[4]  J. Besson,et al.  [Peripheral and spinal mechanisms of nociception]. , 1986, Revue neurologique.

[5]  R. Lipton,et al.  Towards a mechanism-based classification of pain? , 1998, Pain.

[6]  Michael Grüninger,et al.  Introduction , 2002, CACM.

[7]  P. Wall.  Neuropathic pain and injured nerve: central mechanisms. , 1991, British medical bulletin.

[8]  R Dubner,et al.  Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. , 1992, The New England journal of medicine.

[9]  F. Boureau,et al.  Study of verbal description in neuropathic pain , 1990, Pain.

[10]  A. Boulton,et al.  A novel approach to the diagnosis and assessment of symptomatic diabetic neuropathy , 1989, Pain.

[11]  C. Glynn.  An approach to the management of the patient with deafferentation pain , 1989 .

[12]  P. Wall,et al.  Textbook of pain , 1989 .

[13]  R. Portenoy.  Cancer pain: pathophysiology and syndromes , 1992, The Lancet.

[14]  B. Galer,et al.  Development and preliminary validation of a pain measure specific to neuropathic pain , 1997, Neurology.

[15]  J. Bonica,et al.  THE MANAGEMENT OF PAIN , 1954 .

[16]  D. Albe-Fessard,et al.  New trends in referred pain and hyperalgesia , 1993 .

[17]  D. Bowsher.  Neurogenic pain syndromes and their management. , 1991, British medical bulletin.

[18]  J. Campbell,et al.  Weighted needle pinprick sensory thresholds: a simple test of sensory function in diabetic peripheral neuropathy. , 1992, Journal of neurology, neurosurgery, and psychiatry.

[19]  S Lemeshow,et al.  The importance of assessing the fit of logistic regression models: a case study. , 1991, American journal of public health.