Role of polyamines in determining the cellular response to chemotherapeutic agents: modulation of protein kinase CK2 expression and activity

[1]  M. Montenarh.  Cellular regulators of protein kinase CK2 , 2010, Cell and Tissue Research.

[2]  B. Guerra,et al.  Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells , 2010, BMC Cancer.

[3]  J. Dagorn,et al.  A Review of Kinases Implicated in Pancreatic Cancer , 2010, Pancreatology.

[4]  F. Giles,et al.  Emerging drugs in the treatment of pancreatic cancer , 2009, Expert opinion on emerging drugs.

[5]  Alessandra Conversi,et al.  Comparative Analysis , 2009, Encyclopedia of Database Systems.

[6]  Barbara Guerra,et al.  Protein kinase CK2 in human diseases. , 2008, Current medicinal chemistry.

[7]  B. Guerra,et al.  Ability of CK2β to selectively regulate cellular protein kinases , 2008, Molecular and Cellular Biochemistry.

[8]  M. Fakih,et al.  Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine , 2008, Cancer Chemotherapy and Pharmacology.

[9]  L. Marton,et al.  Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases , 2007, Nature Reviews Drug Discovery.

[10]  O. Issinger,et al.  Purification and characterization of the CK2α'-based holoenzyme, an isozyme of CK2α : A comparative analysis , 2006 .

[11]  S. Artim,et al.  A novel protein kinase CK2 substrate indicates CK2 is not directly stimulated by polyamines in vivo. , 2006, Biochemistry.

[12]  O. Issinger,et al.  Primary and secondary interactions between CK2α and CK2β lead to ring-like structures in the crystals of the CK2 holoenzyme , 2005, Molecular and Cellular Biochemistry.

[13]  Wei Zhang,et al.  Combination of 5-Fluorouracil and N1,N11-Diethylnorspermine Markedly Activates Spermidine/Spermine N1-Acetyltransferase Expression, Depletes Polyamines, and Synergistically Induces Apoptosis in Colon Carcinoma Cells* , 2005, Journal of Biological Chemistry.

[14]  E. Gerner,et al.  Polyamines and cancer: old molecules, new understanding , 2004, Nature Reviews Cancer.

[15]  D. Kramer,et al.  Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase. , 2004, Molecular cancer therapeutics.

[16]  H. Wallace,et al.  Inhibitors of polyamine metabolism: Review article , 2004, Amino Acids.

[17]  E. Gerner,et al.  Suppression of polyamine catabolism by activated Ki‐ras in human colon cancer cells , 2004, Molecular carcinogenesis.

[18]  E. Gerner,et al.  Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer* , 2003, Journal of Biological Chemistry.

[19]  O. Issinger,et al.  Modulation of human checkpoint kinase Chk1 by the regulatory β-subunit of protein kinase CK2 , 2003, Oncogene.

[20]  R. Casero,et al.  Spermidine/spermine N1-acetyltransferase (SSAT) activity in human small-cell lung carcinoma cells following transfection with a genomic SSAT construct. , 2003, The Biochemical journal.

[21]  L. Shantz,et al.  Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth. , 2003, Biochemical Society transactions.

[22]  D. Litchfield.  Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. , 2003, The Biochemical journal.

[23]  B. Nelkin,et al.  The Identification of a Cis-element and a Trans-acting Factor Involved in the Response to Polyamines and Polyamine Analogues in the Regulation of the Human Spermidine/Spermine N 1-Acetyltransferase Gene Transcription* , 1998, The Journal of Biological Chemistry.

[24]  J. Hériché,et al.  Binding of Polyamines to an Autonomous Domain of the Regulatory Subunit of Protein Kinase CK2 Induces a Conformational Change in the Holoenzyme , 1997, The Journal of Biological Chemistry.

[25]  S. Hamilton,et al.  Ornithine decarboxylase and polyamines in familial adenomatous polyposis. , 1997, Cancer research.

[26]  O. Issinger,et al.  Influence of indomethacin and difluoromethylornithine on human tumour growth in nude mice. , 1995, European journal of cancer.

[27]  E. Chambaz,et al.  Quaternary Structure of Casein Kinase 2 , 1995, The Journal of Biological Chemistry.

[28]  L. Marton,et al.  Polyamines as targets for therapeutic intervention. , 1995, Annual review of pharmacology and toxicology.

[29]  O. Issinger,et al.  Protein kinase CK2 structure-function relationship: effects of the beta subunit on reconstitution and activity. , 1994, Cellular & molecular biology research.

[30]  J L Cleveland,et al.  The ornithine decarboxylase gene is a transcriptional target of c-Myc. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[31]  E. Chambaz,et al.  Polyamine binding activity of casein kinase II. , 1991, Biochemical and biophysical research communications.

[32]  J. Vinson,et al.  Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells. , 1989, Cancer research.

[33]  C. Glover.  A filamentous form of Drosophila casein kinase II. , 1986, The Journal of biological chemistry.

[34]  B. K. Chang,et al.  Inhibition of growth of human or hamster pancreatic cancer cell lines by alpha-difluoromethylornithine alone and combined with cis-diamminedichloroplatinum(II). , 1984, Cancer research.

[35]  B. K. Chang,et al.  Ornithine decarboxylase enzyme activity in human and hamster pancreatic tumor cell lines. , 1982, Cancer letters.