Disturbances of cerebral protein synthesis and ischemic cell death.

[1]  W. Heiss,et al.  The ischemic penumbra , 1994, Current opinion in neurology.

[2]  K. Hossmann,et al.  Barbiturate promotes post-ischemic reaggregation of polyribosomes in gerbil hippocampus , 1992, Neuroscience Letters.

[3]  G. Mies,et al.  Repeated Negative DC Deflections in Rat Cortex following Middle Cerebral Artery Occlusion are Abolished by MK-801: Effect on Volume of Ischemic Injury , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[4]  W. Paschen,et al.  Threshold relationship between cerebral blood flow, glucose utilization, and energy metabolites during development of stroke in gerbils , 1992, Experimental Neurology.

[5]  K. Hossmann,et al.  Neuronal Damage after Repeated 5 Minutes of Ischemia in the Gerbil is Preceded by Prolonged Impairment of Protein Metabolism , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[6]  F. Welsh,et al.  Regional Expression of Heat Shock Protein-70 mRNA and c-Fos mRNA following Focal Ischemia in Rat Brain , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[7]  Masafumi Tagaya,et al.  ‘Ischemic tolerance’ phenomenon detected in various brain regions , 1991, Brain Research.

[8]  G. Mies,et al.  Ischemic Thresholds of Cerebral Protein Synthesis and Energy State following Middle Cerebral Artery Occlusion in Rat , 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[9]  F. Sharp,et al.  Heat Shock Protein hsp72 Induction in Cortical and Striatal Astrocytes and Neurons following Infarction , 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[10]  M. Moskowitz,et al.  Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex , 1991, Brain Research.

[11]  K Kimura,et al.  Hyperthermia-Induced Neuronal Protection against Ischemic Injury in Gerbils , 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[12]  T. Nowak.  Localization of 70 kDa Stress Protein mRNA Induction in Gerbil Brain after Ischemia , 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[13]  R. Tanzi,et al.  Induction of HSP70 mRNA after transient ischemia in gerbil brain , 1991, Neuroscience Letters.

[14]  R. Tanzi,et al.  Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex , 1991, Neuroscience Letters.

[15]  K. Hossmann,et al.  [14C]Leucine Incorporation into Brain Proteins in Gerbils After Transient Ischemia: Relationship to Selective Vulnerability of Hippocampus , 1991, Journal of neurochemistry.

[16]  T. Kirino,et al.  Induced Tolerance to Ischemia in Gerbil Hippocampal Neurons , 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[17]  M. Beal,et al.  Global ischemia induces NMDA receptor-mediated c-fos expression in neurons resistant to injury in gerbil hippocampus , 1991, Brain Research.

[18]  R. Gwinn,et al.  The temporal profile of 72-kDa heat-shock protein expression following global ischemia , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[19]  Shigeru Sato,et al.  Induction of the ‘zinc finger’ gene after transient focal ischemia in rat cerebral cortex , 1991, Neuroscience Letters.

[20]  Manuel F. Gonzalez,et al.  Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia , 1991, Brain Research Bulletin.

[21]  R. Dempsey,et al.  Ischemic induction of protooncogene expression in gerbil brain. , 1991, Journal of molecular neuroscience : MN.

[22]  Y. Ben-Ari,et al.  Effects of kainic acid-induced seizures and ischemia on c-fos-like proteins in rat brain , 1990, Brain Research.

[23]  K. Goto,et al.  Effects of cycloheximide on delayed neuronal death in rat hippocampus , 1990, Brain Research.

[24]  W. Paschen,et al.  Cerebral Blood Flow, Glucose Utilization, Regional Glucose, and ATP Content during the Maturation Period of Delayed Ischemic Injury in Gerbil Brain , 1990, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[25]  U. Dirnagl,et al.  Nimodipine posttreatment does not increase blood flow in rats with focal cortical ischemia. , 1990, Stroke.

[26]  U. Ungerstedt,et al.  Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus , 1990, Brain Research.

[27]  P. Lipton,et al.  In vitro ischemia and protein synthesis in the rat hippocampal slice: the role of calcium and NMDA receptor activation , 1990, Brain Research.

[28]  P. Lipton,et al.  NMDA receptor activation accelerates ischemic energy depletion in the hippocampal slice and the demonstration of a threshold for ischemic damage to protein synthesis , 1990, Neuroscience Letters.

[29]  J. Hallmayer,et al.  Ornithine Decarboxylase Activity and Putrescine Levels in Reversible Cerebral Ischemia of Mongolian Gerbils: Effect of Barbiturate , 1990, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[30]  T. Nowak,et al.  Heat Shock RNA Levels in Brain and Other Tissues After Hyperthermia and Transient Ischemia , 1990, Journal of neurochemistry.

[31]  S. Theander,et al.  Calcium, Excitotoxins, and Neuronal Death in the Brain a , 1989, Annals of the New York Academy of Sciences.

[32]  J. Mcculloch,et al.  Effect of the NMDA Antagonist MK-801 on Local Cerebral Blood Flow in Focal Cerebral Ischaemia in the Rat , 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  W. Heiss,et al.  Ischemic Flow Threshold for Extracellular Glutamate Increase in Cat Cortex , 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[34]  K. Hossmann,et al.  Effect of barbiturate treatment on post-ischemic protein biosynthesis in gerbil brain , 1989, Journal of the Neurological Sciences.

[35]  G. Mies,et al.  Ischemic threshold of brain protein synthesis after unilateral carotid artery occlusion in gerbils. , 1989, Stroke.

[36]  J. Deckert,et al.  Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global cerebral ischemia: an in situ hybridization study , 1989, Brain Research.

[37]  B. Dwyer,et al.  Synthesis of the major inducible heat shock protein in rat hippocampus after neonatal hypoxia-ischemia , 1989, Experimental Neurology.

[38]  A. Nagaoka,et al.  Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemia , 1989, Neuroscience Letters.

[39]  M. Ginsberg,et al.  (S)‐Emopamil, a novel calcium channel blocker and serotonin S2 antagonist, markedly reduces infarct size following middle cerebral artery occlusion in the rat , 1988, Neurology.

[40]  K. Abe,et al.  Recovery from Edema and of Protein Synthesis Differs Between the Cortex and Caudate Following Transient Focal Cerebral Ischemia in Rats , 1988, Journal of neurochemistry.

[41]  D. Graham,et al.  Focal Cerebral Ischaemia in the Cat: Treatment with the Glutamate Antagonist MK-801 after Induction of Ischaemia , 1988, Journal of Cerebral Blood Flow and Metabolism.

[42]  W. Paschen,et al.  Polyamines in cerebral ischemia. , 1988, Neurochemical pathology.

[43]  K. Hossmann,et al.  Effect of autologous clot embolism on regional protein biosynthesis of monkey brain. , 1988, Stroke.

[44]  A. Alcázar,et al.  Specific phosphorylation of the beta subunit of eIF-2 factor from brain by three different protein kinases. , 1988, Biochemical and biophysical research communications.

[45]  T. Nowak,et al.  Experimental Model for Repetitive Ischemic Attacks in the Gerbil: The Cumulative Effect of Repeated Ischemic Insults , 1987, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[46]  G. Mies,et al.  Calcium in the mitochondria following brief ischemia of gerbil brain , 1987, Neuroscience Letters.

[47]  T. Yoshimine,et al.  Autoradiographic Study of Regional Protein Synthesis in Focal Cerebral Ischemia with TCA Wash and Image Subtraction Techniques , 1987, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[48]  K. Hossmann,et al.  Effect of 5-minute ischemia on regional pH and energy state of the gerbil brain: relation to selective vulnerability of the hippocampus. , 1987, Stroke.

[49]  B. Dwyer,et al.  Focal protein synthesis inhibition in a model of neonatal hypoxic-ischemic brain injury , 1987, Experimental Neurology.

[50]  K. Hossmann,et al.  Recovery of integrative central nervous function after one hour global cerebro-circulatory arrest in normothermic cat , 1987, Journal of the Neurological Sciences.

[51]  宗像 克治.  Selective vulnerability of hippocampus : ribosomal aggregation, protein synthesis and tissue pH , 1987 .

[52]  M. Chavko,et al.  Molecular mechanisms of ischemic damage of spinal cord. , 1987, Gerontology.

[53]  G. Dienel,et al.  Protein Synthesis in Postischemic Rat Brain: A Two-Dimensional Electrophoretic Analysis , 1986, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[54]  J Astrup,et al.  Infarct Rim: Effect of Hyperglycemia on Direct Current Potential and [14C]2-Deoxyglucose Phosphorylation , 1986, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[55]  G. Dienel,et al.  Synthesis of Heat Shock Proteins in Rat Brain Cortex after Transient Ischemia , 1986, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[56]  W. Pulsinelli,et al.  Selective Gene Expression in Focal Cerebral Ischemia , 1986, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[57]  K. Hossmann,et al.  Recovery of Monkey Brain after Prolonged Ischemia. II. Protein Synthesis and Morphological Alterations , 1986, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[58]  T. Nowak.  Synthesis of a Stress Protein Following Transient Ischemia in the Gerbil , 1985, Journal of neurochemistry.

[59]  A. Hamberger,et al.  Ischemia-Induced Shift of Inhibitory and Excitatory Amino Acids from Intra- to Extracellular Compartments , 1985, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[60]  W. Paschen,et al.  Regional cerebral blood flow, glucose metabolism, protein synthesis, serum protein extravasation, and content of biochemical substrates in stroke-prone spontaneously hypertensive rats. , 1985, Stroke.

[61]  W. Paschen,et al.  Multiparametric Imaging of Blood Flow and Metabolism after Middle Cerebral Artery Occlusion in Cats , 1985, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[62]  T. Nowak,et al.  Changes in Brain Energy Metabolism and Protein Synthesis Following Transient Bilateral Ischemia in the Gerbil , 1985, Journal of neurochemistry.

[63]  G. Dienel,et al.  Temporal Profiles of Proteins Responsive to Transient Ischemia , 1985, Journal of neurochemistry.

[64]  K. Hossmann,et al.  Cerebral protein synthesis and ischemia. , 1985, Progress in brain research.

[65]  D. Nicholls.  A role for the mitochondrion in the protection of cells against calcium overload? , 1985, Progress in brain research.

[66]  H. Benveniste,et al.  Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis , 1984, Journal of neurochemistry.

[67]  C. Petito,et al.  Sequential Development of Reversible and Irreversible Neuronal Damage Following Cerebral Ischemia , 1984, Journal of neuropathology and experimental neurology.

[68]  S. Ochoa,et al.  Activation of the heme-stabilized translational inhibitor of reticulocyte lysates by calcium ions and phospholipid. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[69]  W. Merrick,et al.  Phospholipid‐sensitive Ca2+‐dependent protein kinase phosphorylates the β subunit of eukaryotic initiation factor 2 (eIF‐2) , 1983, FEBS letters.

[70]  S. Lindquist,et al.  The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels , 1982, Cell.

[71]  Takaaki Kirino,et al.  Delayed neuronal death in the gerbil hippocampus following ischemia , 1982, Brain Research.

[72]  B. Siesjö,et al.  Thresholds in cerebral ischemia - the ischemic penumbra. , 1981, Stroke.

[73]  L. Symon,et al.  Changes in Extracellular Calcium Activity in Cerebral Ischaemia , 1981, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[74]  K. Morimoto.  Cerebral Ischemia in Gerbils: Polyribosomal Function During Progression and Recovery , 1981, Stroke.

[75]  M. Chavko,et al.  Incorporation of 14C-leucine into the proteins of spinal ganglia in vivo under conditions of partial ischaemia. , 1981, Physiologia Bohemoslovaca.

[76]  W. Anderson,et al.  The regulation of initiation of mammalian protein synthesis. , 1981, Progress in nucleic acid research and molecular biology.

[77]  W. Pulsinelli,et al.  Regional Protein Synthesis in Rat Brain Following Acute Hemispheric Ischemia , 1980, Journal of neurochemistry.

[78]  T. Yanagihara,et al.  Experimental stroke in gerbils: Effect on translation and transcription , 1978, Brain Research.

[79]  T. Yanagihara,et al.  FURTHER EVALUATION OF POLYPEPTIDE SYNTHESIS IN CEREBRAL ANOXIA, HYPOXIA AND ISCHEMIA , 1978, Journal of neurochemistry.

[80]  K. Hossmann,et al.  THE EFFECT OF ISCHAEMIA AND RECIRCULATION ON PROTEIN SYNTHESIS IN THE RAT BRAIN , 1977, Journal of neurochemistry.

[81]  K. Hossmann,et al.  Cation Activities in Reversible Ischemia of the Cat Brain , 1977, Stroke.

[82]  T. Yanagihara.  CEREBRAL ANOXIA: EFFECT ON NEURON‐GLIA FRACTIONS AND POLYSOMAL PROTEIN SYNTHESIS , 1976, Journal of neurochemistry.

[83]  K. Hossmann,et al.  Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery , 1975, Brain Research.

[84]  C. Wasterlain.  BRAIN RIBOSOMES IN INTRACRANIAL HYPERTENSION 1 , 1974, Journal of neurochemistry.

[85]  J. Hartmann,et al.  Disaggregation of Polyribosomes in Intact Gerbils Following Ischemia. An Ultrastructural Study , 1973, Stroke.

[86]  K. Hossmann,et al.  Protein synthesis in the cat brain after prolonged cerebral ischemia. , 1971, Brain research.

[87]  M. Kowada,et al.  Cerebral ischemia. II. The no-reflow phenomenon. , 1968, The American journal of pathology.

[88]  O. H. Lowry,et al.  EFFECT OF ISCHEMIA ON KNOWN SUBSTRATES AND COFACTORS OF THE GLYCOLYTIC PATHWAY IN BRAIN. , 1964, The Journal of biological chemistry.