Two Waves of Platelet Secretion Induced by Thromboxane A2 Receptor and a Critical Role for Phosphoinositide 3-Kinases*
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[1] N. Watanabe,et al. Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation. , 2003, Blood.
[2] F. Hofmann,et al. A Stimulatory Role for cGMP-Dependent Protein Kinase in Platelet Activation , 2003, Cell.
[3] Jianguo Jin,et al. Coordinated Signaling through Both G12/13 and Gi Pathways Is Sufficient to Activate GPIIb/IIIa in Human Platelets* , 2002, The Journal of Biological Chemistry.
[4] B. Nieswandt,et al. Costimulation of Gi- and G12/G13-mediated Signaling Pathways Induces Integrin αIIbβ3 Activation in Platelets* , 2002, The Journal of Biological Chemistry.
[5] C. Kahn,et al. Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways , 2002, Cell.
[6] S. Jackson,et al. Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin αIIbβ3 , 2002 .
[7] Xiaoping Du,et al. A Mitogen-activated Protein Kinase-dependent Signaling Pathway in the Activation of Platelet Integrin αIIbβ3 * , 2001, The Journal of Biological Chemistry.
[8] E. Hirsch,et al. Resistance to thromboembolism in PI3Kγ‐deficient mice , 2001 .
[9] S. Kunapuli,et al. Potentiation of Thromboxane A2-induced Platelet Secretion by Gi Signaling through the Phosphoinositide-3 Kinase Pathway , 2001, Thrombosis and Haemostasis.
[10] B. Payrastre,et al. A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase. , 1999, Blood.
[11] Xiaoping Du,et al. Analysis of the Roles of 14-3-3 in the Platelet Glycoprotein Ib-IX–Mediated Activation of Integrin αIIbβ3 Using a Reconstituted Mammalian Cell Expression Model , 1999, The Journal of cell biology.
[12] S. Kunapuli,et al. Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. , 1999, The Journal of biological chemistry.
[13] K. Antonakis,et al. Identification of Gα13 as One of the G-proteins That Couple to Human Platelet Thromboxane A2 Receptors* , 1999, The Journal of Biological Chemistry.
[14] M. Simon,et al. Activation of G12/G13 Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets , 1999, The Journal of cell biology.
[15] R. Wetzker,et al. A Novel Mitogenic Signaling Pathway of Bradykinin in the Human Colon Carcinoma Cell Line SW-480 Involves Sequential Activation of a Gq/11 Protein, Phosphatidylinositol 3-Kinase β, and Protein Kinase Cε* , 1998, The Journal of Biological Chemistry.
[16] Ching-shih Chen,et al. A Novel Integrin-activated Pathway Forms PKB/Akt- stimulatory Phosphatidylinositol 3,4-Bisphosphate via Phosphatidylinositol 3-Phosphate in Platelets* , 1998, The Journal of Biological Chemistry.
[17] S. Hoshino,et al. Heterodimeric Phosphoinositide 3-Kinase Consisting of p85 and p110β Is Synergistically Activated by the βγ Subunits of G Proteins and Phosphotyrosyl Peptide* , 1997, The Journal of Biological Chemistry.
[18] N. Dhanasekaran,et al. Platelet signal transduction defect with Gα subunit dysfunction and diminished Gαq in a patient with abnormal platelet responses , 1997 .
[19] P. Hawkins,et al. The Gβγ Sensitivity of a PI3K Is Dependent upon a Tightly Associated Adaptor, p101 , 1997, Cell.
[20] S. Rittenhouse. Phosphoinositide 3-kinase activation and platelet function. , 1996, Blood.
[21] S. Shattil,et al. Phosphoinositide 3-Kinase and p85/Phosphoinositide 3-Kinase in Platelets , 1996, The Journal of Biological Chemistry.
[22] S. Volinia,et al. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. , 1995, Science.
[23] A. Toker,et al. Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation , 1995, The Journal of Biological Chemistry.
[24] I. Gout,et al. Sequestration of a G-protein βγ Subunit or ADP-ribosylation of Rho Can Inhibit Thrombin-induced Activation of Platelet Phosphoinositide 3-Kinases (*) , 1995, The Journal of Biological Chemistry.
[25] S. Narumiya,et al. Functional reconstitution of platelet thromboxane A2 receptors with Gq and Gi2 in phospholipid vesicles. , 1994, Molecular pharmacology.
[26] G. Schultz,et al. G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[27] G. L. Le Breton,et al. Identification of Gq as one of the G-proteins which copurify with human platelet thromboxane A2/prostaglandin H2 receptors. , 1993, The Journal of biological chemistry.
[28] S. Coughlin,et al. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase. , 1992, The Journal of biological chemistry.
[29] G. L. Le Breton,et al. Purification of the human blood platelet thromboxane A2/prostaglandin H2 receptor protein. , 1992, Biochemical pharmacology.
[30] A. Shenker,et al. The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. , 1991, Transactions of the Association of American Physicians.
[31] Xiaoping Du,et al. Ligands “activate” integrin α IIb β 3 (platelet GPIIb-IIIa) , 1991, Cell.
[32] S. Nakanishi,et al. Cloning and expression of cDNA for a human thromboxane A2 receptor , 1991, Nature.
[33] G. Kucera,et al. Human platelets form 3-phosphorylated phosphoinositides in response to alpha-thrombin, U46619, or GTP gamma S. , 1990, The Journal of biological chemistry.
[34] S. Narumiya,et al. Purification of the thromboxane A2/prostaglandin H2 receptor from human blood platelets. , 1989, The Journal of biological chemistry.
[35] M. Caton,et al. Prostaglandins and thromboxanes. , 1979, Progress in medicinal chemistry.
[36] R. Feinman,et al. Prostaglandin endoperoxides and thromboxane A2 can induce platelet aggregation in the absence of secretion , 1977, Nature.
[37] P. Needleman,et al. Thromboxanes: selective biosynthesis and distinct biological properties. , 1976, Science.
[38] M. Hamberg,et al. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. , 1975, Proceedings of the National Academy of Sciences of the United States of America.