Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease

[1]  J. Trojanowski,et al.  Concomitant TAR-DNA-Binding Protein 43 Pathology Is Present in Alzheimer Disease and Corticobasal Degeneration but Not in Other Tauopathies , 2008, Journal of neuropathology and experimental neurology.

[2]  E. Head,et al.  Lack of Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease after Overexpression of the Anti-Apoptotic Protein Bcl-2 , 2008, The Journal of Neuroscience.

[3]  Phillip B. Jones,et al.  In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons , 2008, The Journal of Neuroscience.

[4]  C. Jack,et al.  Progressive aphasia secondary to Alzheimer disease vs FTLD pathology , 2008, Neurology.

[5]  H. Arai,et al.  Concurrence of TDP-43, tau and α-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies , 2007, Brain Research.

[6]  J. Trojanowski,et al.  TDP-43 Proteinopathies: Neurodegenerative Protein Misfolding Diseases without Amyloidosis , 2007, Neurosignals.

[7]  L. Petrucelli,et al.  Progranulin Mediates Caspase-Dependent Cleavage of TAR DNA Binding Protein-43 , 2007, The Journal of Neuroscience.

[8]  J. Trojanowski,et al.  TDP-43 proteinopathy: the neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease , 2007, Acta Neuropathologica.

[9]  D. Dickson,et al.  TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease , 2007, Annals of neurology.

[10]  Julia Thom Oxford,et al.  Calpain-Cleavage of α-Synuclein : Connecting Proteolytic Processing to Disease-Linked Aggregation , 2007 .

[11]  Bruce L. Miller,et al.  Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis , 2006, Science.

[12]  K. Jellinger Challenges in neuronal apoptosis. , 2006, Current Alzheimer research.

[13]  Kwang-Ho Ha,et al.  Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain. , 2006, The American journal of pathology.

[14]  A. LeBlanc,et al.  The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death. , 2005, Current Alzheimer research.

[15]  C. Cotman,et al.  The Role of Caspase Cleavage of Tau in Alzheimer Disease Neuropathology , 2005, Journal of neuropathology and experimental neurology.

[16]  C. Cotman,et al.  Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. , 2004, The Journal of clinical investigation.

[17]  E. Buratti,et al.  Nuclear factor TDP-43 binds to the polymorphic TG repeats in CFTR intron 8 and causes skipping of exon 9: a functional link with disease penetrance. , 2004, American journal of human genetics.

[18]  R. Berry,et al.  Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[19]  C. Cotman,et al.  Caspase Activation in the Alzheimer's Disease Brain: Tortuous and Torturous. , 2002, Drug news & perspectives.

[20]  C. Cotman,et al.  Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain , 2002, Neurobiology of Disease.

[21]  William H. Nesse,et al.  Activation of Caspase-8 in the Alzheimer's Disease Brain , 2001, Neurobiology of Disease.

[22]  G. Cole,et al.  Caspase‐cleaved actin (fractin) immunolabelling of Hirano bodies , 2000, Neuropathology and applied neurobiology.

[23]  David Smith,et al.  Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation , 1999, Cell.

[24]  H. Vinters,et al.  Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease. , 1998, The American journal of pathology.

[25]  A Hirano,et al.  Hirano bodies and related neuronal inclusions , 1994, Neuropathology and applied neurobiology.

[26]  E. Masliah,et al.  Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. , 2007, The American journal of pathology.

[27]  C. Cotman,et al.  Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease. , 2001, The American journal of pathology.

[28]  G. Robertson,et al.  Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. , 1999, Cell.