Nighttime insomnia symptoms and perceived health in the America Insomnia Survey (AIS).

STUDY OBJECTIVES To explore the distribution of the 4 cardinal nighttime symptoms of insomnia-difficulty initiating sleep (DIS), difficulty maintaining sleep (DMS), early morning awakening (EMA), and nonrestorative sleep (NRS)-in a national sample of health plan members and the associations of these nighttime symptoms with sociodemographics, comorbidity, and perceived health. DESIGN/SETTING/PARTICIPANTS Cross-sectional telephone survey of 6,791 adult respondents. INTERVENTION None. MEASUREMENTS/RESULTS Current insomnia was assessed using the Brief Insomnia Questionnaire (BIQ)-a fully structured validated scale generating diagnoses of insomnia using DSM-IV-TR, ICD-10, and RDC/ICSD-2 inclusion criteria. DMS (61.0%) and EMA (52.2%) were more prevalent than DIS (37.7%) and NRS (25.2%) among respondents with insomnia. Sociodemographic correlates varied significantly across the 4 symptoms. All 4 nighttime symptoms were significantly related to a wide range of comorbid physical and mental conditions. All 4 also significantly predicted decrements in perceived health both in the total sample and among respondents with insomnia after adjusting for comorbid physical and mental conditions. Joint associations of the 4 symptoms predicting perceived health were additive and related to daytime distress/impairment. Individual-level associations were strongest for NRS. At the societal level, though, where both prevalence and strength of individual-level associations were taken into consideration, DMS had the strongest associations. CONCLUSIONS The extent to which nighttime insomnia symptoms are stable over time requires future long-term longitudinal study. Within the context of this limitation, the results suggest that core nighttime symptoms are associated with different patterns of risk and perceived health and that symptom-based subtyping might have value.

[1]  C. Morin,et al.  Incidence and risk factors of insomnia in a population-based sample. , 2009, Sleep.

[2]  A. Harvey,et al.  The subjective meaning of sleep quality: a comparison of individuals with and without insomnia. , 2008, Sleep.

[3]  M. Ganguli,et al.  Prevalence and Persistence of Sleep Complaints in a Rural Older Community Sample: The MoVIES Project , 1996, Journal of the American Geriatrics Society.

[4]  Ronald C. Kessler,et al.  Prevalence and Perceived Health Associated with Insomnia Based on DSM-IV-TR; International Statistical Classification of Diseases and Related Health Problems, Tenth Revision; and Research Diagnostic Criteria/International Classification of Sleep Disorders, Second Edition Criteria: Results from the A , 2011, Biological Psychiatry.

[5]  Duanping Liao,et al.  Insomnia with objective short sleep duration is associated with a high risk for hypertension. , 2009, Sleep.

[6]  S. Stewart-Brown,et al.  Estimating health needs: the impact of a checklist of conditions and quality of life measurement on health information derived from community surveys. , 2001, Journal of public health medicine.

[7]  J. Ware,et al.  Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: results from the IQOLA Project. International Quality of Life Assessment. , 1998, Journal of clinical epidemiology.

[8]  C. Guilleminault,et al.  Prevalence of insomnia in a survey of 12 778 adults in France , 2000, Journal of sleep research.

[9]  M. Stein,et al.  Impairment Associated With Sleep Problems in the Community: Relationship to Physical and Mental Health Comorbidity , 2008, Psychosomatic medicine.

[10]  E. Simonsick,et al.  Incidence and remission of insomnia among elderly adults: an epidemiologic study of 6,800 persons over three years. , 1999, Sleep.

[11]  M. Stein,et al.  Relationship of anxiety disorders, sleep quality, and functional impairment in a community sample. , 2009, Journal of psychiatric research.

[12]  Shumei S. Sun,et al.  Sleep disturbance in relation to health-related quality of life in adults: The fels longitudinal study , 2009, The journal of nutrition, health & aging.

[13]  D. Léger,et al.  An international survey of insomnia: under-recognition and under-treatment of a polysymptomatic condition , 2005, Current medical research and opinion.

[14]  J. Ware,et al.  A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. , 1996, Medical care.

[15]  C. Morin,et al.  Epidemiology of insomnia: prevalence, self-help treatments, consultations, and determinants of help-seeking behaviors. , 2006, Sleep medicine.

[16]  Y. Lecrubier,et al.  Form, frequency and burden of sleep problems in general health care: a report from the WHO Collaborative Study on Psychological Problems in General Health Care , 1996, European Psychiatry.

[17]  S. Redline,et al.  The DSM-V sleep-wake disorders nosology: an update and an invitation to the sleep community. , 2010, Sleep.

[18]  C. Guilleminault,et al.  How Age and Daytime Activities Are Related to Insomnia in the General Population: Consequences for Older People , 2001, Journal of the American Geriatrics Society.

[19]  Michael Baker,et al.  What Do Self-Reported, Objective, Measures of Health Measure? , 2001, The Journal of Human Resources.

[20]  Sonia Ancoli-Israel,et al.  Recommendations for a standard research assessment of insomnia. , 2006, Sleep.

[21]  D. Segal Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) , 2010 .

[22]  E. Bixler,et al.  Insomnia with short sleep duration and mortality: the Penn State cohort. , 2010, Sleep.

[23]  D. Neubauer,et al.  An international survey of sleeping problems in the general population , 2008, Current medical research and opinion.

[24]  I. Chen,et al.  Impact of insomnia on future functioning of adolescents. , 2002, Journal of psychosomatic research.

[25]  C. Guilleminault,et al.  Medical and socio-professional impact of insomnia. , 2002, Sleep.

[26]  Daniel J. Taylor,et al.  Epidemiology of insomnia, depression, and anxiety. , 2005, Sleep.

[27]  S. Retchin,et al.  Evaluation of National Health Interview Survey diagnostic reporting. , 1994, Vital and health statistics. Series 2, Data evaluation and methods research.

[28]  B. Löwe,et al.  A brief measure for assessing generalized anxiety disorder: the GAD-7. , 2006, Archives of internal medicine.

[29]  E. Stepanski,et al.  Recent developments in the classification, evaluation, and treatment of insomnia. , 2006, Chest.

[30]  C. Guilleminault,et al.  Epidemiology of Sleep Disorders , 2005 .

[31]  P. F. Adams,et al.  Summary health statistics for the U.S. population: National Health Interview Survey, 2000. , 2003, Vital and health statistics. Series 10, Data from the National Health Survey.

[32]  M. Bonnet,et al.  Hyperarousal and insomnia: state of the science. , 2010, Sleep medicine reviews.

[33]  S. Øverland,et al.  The epidemiology of insomnia: associations with physical and mental health. The HUNT-2 study. , 2009, Journal of psychosomatic research.

[34]  Daniel J. Taylor,et al.  Comorbidity of chronic insomnia with medical problems. , 2007, Sleep.

[35]  B. Vaughn,et al.  Chapter 57 – Cardinal Manifestations of Sleep Disorders , 2011 .

[36]  W. Pigeon Insomnia as a predictor of depression: do insomnia subtypes matter? , 2010, Sleep.

[37]  C. Guilleminault,et al.  Chapter 21 – Epidemiology of Sleep Disorders , 2009 .

[38]  Christian Guilleminault,et al.  SF-36: Evaluation of Quality of Life in Severe and Mild Insomniacs Compared With Good Sleepers , 2001, Psychosomatic medicine.

[39]  S. Weyerer,et al.  Sleep onset insomnia, sleep maintaining insomnia and insomnia with early morning awakening--temporal stability of subtypes in a longitudinal study on general practice attenders. , 1994, Sleep.

[40]  D. Revicki,et al.  Gastroparesis Cardinal Symptom Index (GCSI): Development and validation of a patient reported assessment of severity of gastroparesis symptoms , 2004, Quality of Life Research.

[41]  P. Gander,et al.  Who reports insomnia? Relationships with age, sex, ethnicity, and socioeconomic deprivation. , 2004, Sleep.

[42]  M. Northridge,et al.  Public health methods--attributable risk as a link between causality and public health action. , 1995, American journal of public health.

[43]  K. Sarsour,et al.  Subtypes of Sleep Disturbance: Associations Among Symptoms, Comorbidities, Treatment, and Medical Costs , 2010, Behavioral sleep medicine.

[44]  D. Sheehan,et al.  The measurement of disability. , 1996 .

[45]  Daniel J. Taylor,et al.  Chapter 76 – Insomnia: Epidemiology and Risk Factors , 2010 .

[46]  J. Brazier The Short-Form 36 (SF-36) Health Survey and Its Use in Pharmacoeconomic Evaluation , 1995, PharmacoEconomics.

[47]  K. Strohl,et al.  Using the Berlin Questionnaire To Identify Patients at Risk for the Sleep Apnea Syndrome , 1999, Annals of Internal Medicine.

[48]  P. Croft,et al.  Epidemiology of insomnia: a longitudinal study in a UK population. , 2007, Sleep.

[49]  J. Brazier,et al.  The Estimation of a Preference-Based Measure of Health From the SF-12 , 2004, Medical care.

[50]  Duanping Liao,et al.  Insomnia With Objective Short Sleep Duration Is Associated With Type 2 Diabetes , 2009, Diabetes Care.

[51]  R. Bootzin,et al.  Derivation of research diagnostic criteria for insomnia: report of an American Academy of Sleep Medicine Work Group. , 2004, Sleep.

[52]  Yasuhiko Saito,et al.  Association between depression and insomnia subtypes: a longitudinal study on the elderly in Japan. , 2010, Sleep.

[53]  J. Markowitz,et al.  The 16-Item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression , 2003, Biological Psychiatry.

[54]  M. Ohayon Prevalence and correlates of nonrestorative sleep complaints. , 2005, Archives of internal medicine.

[55]  M. Uchiyama,et al.  An epidemiological study of insomnia among the Japanese general population. , 2000, Sleep.

[56]  J. Daly,et al.  Risk factors for insomnia in a rural population. , 2007, Annals of epidemiology.

[57]  Anne Germain,et al.  Focusing on the Experience of Insomnia , 2005, Behavioral sleep medicine.

[58]  Reliability and validity of the brief insomnia questionnaire in the America insomnia survey. , 2010 .