Automatic Breast Ultrasound Image Segmentation: A Survey

Breast cancer is one of the leading causes of cancer death among women worldwide. In clinical routine, automatic breast ultrasound (BUS) image segmentation is very challenging and essential for cancer diagnosis and treatment planning. Many BUS segmentation approaches have been studied in the last two decades, and have been proved to be effective on private datasets. Currently, the advancement of BUS image segmentation seems to meet its bottleneck. The improvement of the performance is increasingly challenging, and only few new approaches were published in the last several years. It is the time to look at the field by reviewing previous approaches comprehensively and to investigate the future directions. In this paper, we study the basic ideas, theories, pros and cons of the approaches, group them into categories, and extensively review each category in depth by discussing the principles, application issues, and advantages/disadvantages.

[1]  Thomas Hofmann,et al.  Support vector machine learning for interdependent and structured output spaces , 2004, ICML.

[2]  D. Boukerroui,et al.  Multiresolution texture based adaptive clustering algorithm for breast lesion segmentation. , 1998, European journal of ultrasound : official journal of the European Federation of Societies for Ultrasound in Medicine and Biology.

[3]  V. Caselles,et al.  A geometric model for active contours in image processing , 1993 .

[4]  Radford M. Neal Pattern Recognition and Machine Learning , 2007, Technometrics.

[5]  Zhuowen Tu,et al.  Probabilistic boosting-tree: learning discriminative models for classification, recognition, and clustering , 2005, Tenth IEEE International Conference on Computer Vision (ICCV'05) Volume 1.

[6]  Tzong-Jer Chen,et al.  Fuzzy c-means clustering with spatial information for image segmentation , 2006, Comput. Medical Imaging Graph..

[7]  R. Chang,et al.  Tumor detection in automated breast ultrasound images using quantitative tissue clustering. , 2014, Medical physics.

[8]  David A. McAllester,et al.  Object Detection with Discriminatively Trained Part Based Models , 2010, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[9]  Scott T. Acton,et al.  Speckle reducing anisotropic diffusion , 2002, IEEE Trans. Image Process..

[10]  Annupan Rodtook,et al.  Continuous force field analysis for generalized gradient vector flow field , 2010, Pattern Recognit..

[11]  N. Otsu A threshold selection method from gray level histograms , 1979 .

[12]  Sven J. Dickinson,et al.  TurboPixels: Fast Superpixels Using Geometric Flows , 2009, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[13]  Sheng-Fang Huang,et al.  Neural network analysis applied to tumor segmentation on 3D breast ultrasound images , 2008, 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[14]  Anthony J. Yezzi,et al.  A geometric snake model for segmentation of medical imagery , 1997, IEEE Transactions on Medical Imaging.

[15]  Jürgen Schmidhuber,et al.  Multi-column deep neural networks for image classification , 2012, 2012 IEEE Conference on Computer Vision and Pattern Recognition.

[16]  Donald Geman,et al.  Stochastic Relaxation, Gibbs Distributions, and the Bayesian Restoration of Images , 1984, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[17]  Peyman Milanfar,et al.  A Tour of Modern Image Filtering: New Insights and Methods, Both Practical and Theoretical , 2013, IEEE Signal Processing Magazine.

[18]  Patrick O. Glauner Deep Convolutional Neural Networks for Smile Recognition , 2015, ArXiv.

[19]  Leo Grady,et al.  A Seeded Image Segmentation Framework Unifying Graph Cuts And Random Walker Which Yields A New Algorithm , 2007, 2007 IEEE 11th International Conference on Computer Vision.

[20]  Vladimir Vezhnevets,et al.  “GrowCut”-Interactive Multi-Label N-D Image Segmentation By Cellular Automata , 2005 .

[21]  Fei Xu,et al.  A saliency model for automated tumor detection in breast ultrasound images , 2015, 2015 IEEE International Conference on Image Processing (ICIP).

[22]  Xianglong Tang,et al.  Multiple-domain knowledge based MRF model for tumor segmentation in breast ultrasound images , 2012, 2012 19th IEEE International Conference on Image Processing.

[23]  Heng-Da Cheng,et al.  Completely automatic segmentation for breast ultrasound using multiple-domain features , 2010, 2010 IEEE International Conference on Image Processing.

[24]  Olga Veksler,et al.  Fast approximate energy minimization via graph cuts , 2001, Proceedings of the Seventh IEEE International Conference on Computer Vision.

[25]  Chunming Li,et al.  Level set evolution without re-initialization: a new variational formulation , 2005, 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05).

[26]  Pierrick Coupé,et al.  Nonlocal Means-Based Speckle Filtering for Ultrasound Images , 2009, IEEE Transactions on Image Processing.

[27]  Fei Xu,et al.  Neutro-Connectedness Cut , 2015, IEEE Transactions on Image Processing.

[28]  Ying Wu,et al.  Ultrasound lesion segmentation using clinical knowledge-driven constrained level set , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[29]  A. Jemal,et al.  Cancer statistics, 2015 , 2015, CA: a cancer journal for clinicians.

[30]  José M. N. Leitão,et al.  Wall position and thickness estimation from sequences of echocardiographic images , 1996, IEEE Trans. Medical Imaging.

[31]  Liang Gao,et al.  Phase- and GVF-Based Level Set Segmentation of Ultrasonic Breast Tumors , 2012, J. Appl. Math..

[32]  L Leija,et al.  Computerized lesion segmentation of breast ultrasound based on marker-controlled watershed transformation. , 2009, Medical physics.

[33]  Xianglong Tang,et al.  Probability density difference-based active contour for ultrasound image segmentation , 2010, Pattern Recognit..

[34]  Jiangwen Deng,et al.  A fast level set method for segmentation of low contrast noisy biomedical images , 2002, Pattern Recognit. Lett..

[35]  Samuel J. Magny,et al.  Breast Imaging Reporting and Data System , 2020, Definitions.

[36]  Ronald Fedkiw,et al.  Level set methods and dynamic implicit surfaces , 2002, Applied mathematical sciences.

[37]  Ruey-Feng Chang,et al.  Automatic ultrasound segmentation and morphology based diagnosis of solid breast tumors , 2004, Breast Cancer Research and Treatment.

[38]  Jerry L. Prince,et al.  Generalized gradient vector flow external forces for active contours , 1998, Signal Process..

[39]  Hee Chan Kim,et al.  Computer-aided diagnosis of solid breast nodules: use of an artificial neural network based on multiple sonographic features , 2004, IEEE Trans. Medical Imaging.

[40]  Vladlen Koltun,et al.  Efficient Inference in Fully Connected CRFs with Gaussian Edge Potentials , 2011, NIPS.

[41]  Stochastic Relaxation , 2014, Computer Vision, A Reference Guide.

[42]  Qiang Wang,et al.  Learning a Structured Graphical Model with Boosted Top-Down Features for Ultrasound Image Segmentation , 2013, MICCAI.

[43]  K. Boone,et al.  Effect of skin impedance on image quality and variability in electrical impedance tomography: a model study , 1996, Medical and Biological Engineering and Computing.

[44]  Jianjun Yuan,et al.  Active contour driven by local divergence energies for ultrasound image segmentation , 2013, IET Image Process..

[45]  Dong Yu,et al.  Deep Learning: Methods and Applications , 2014, Found. Trends Signal Process..

[46]  Laurent D. Cohen,et al.  Finite-Element Methods for Active Contour Models and Balloons for 2-D and 3-D Images , 1993, IEEE Trans. Pattern Anal. Mach. Intell..

[47]  Laurent D. Cohen,et al.  On active contour models and balloons , 1991, CVGIP Image Underst..

[48]  Ernesto Bribiesca,et al.  An easy measure of compactness for 2D and 3D shapes , 2008, Pattern Recognit..

[49]  Thrasyvoulos N. Pappas,et al.  An Adaptive Clustering Algorithm For Image Segmentation , 1988, [1988 Proceedings] Second International Conference on Computer Vision.

[50]  Ling Zhang,et al.  Automated breast cancer detection and classification using ultrasound images: A survey , 2010, Pattern Recognit..

[51]  P Kovesi,et al.  Phase congruency: A low-level image invariant , 2000, Psychological research.

[52]  Robert Marti,et al.  Simultaneous Lesion Segmentation and Bias Correction in Breast Ultrasound Images , 2011, IbPRIA.

[53]  Serge Beucher,et al.  The Morphological Approach to Segmentation: The Watershed Transformation , 2018, Mathematical Morphology in Image Processing.

[54]  Serge Beucher,et al.  Use of watersheds in contour detection , 1979 .

[55]  D. R. Fulkerson,et al.  Maximal Flow Through a Network , 1956 .

[56]  Heng-Da Cheng,et al.  A novel automatic seed point selection algorithm for breast ultrasound images , 2008, 2008 19th International Conference on Pattern Recognition.

[57]  J. C. Dunn,et al.  A Fuzzy Relative of the ISODATA Process and Its Use in Detecting Compact Well-Separated Clusters , 1973 .

[58]  Allen R. Tannenbaum,et al.  Localizing Region-Based Active Contours , 2008, IEEE Transactions on Image Processing.

[59]  Gilles Bertrand,et al.  Watershed Cuts: Minimum Spanning Forests and the Drop of Water Principle , 2009, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[60]  D. Shen,et al.  Computer-Aided Diagnosis with Deep Learning Architecture: Applications to Breast Lesions in US Images and Pulmonary Nodules in CT Scans , 2016, Scientific Reports.

[61]  Zhihua Liu,et al.  A robust region-based active contour model with point classification for ultrasound breast lesion segmentation , 2013, Medical Imaging.

[62]  Lian-Wen Jin,et al.  A robust graph-based segmentation method for breast tumors in ultrasound images. , 2012, Ultrasonics.

[63]  Dimitris N. Metaxas,et al.  Combining low-, high-level and empirical domain knowledge for automated segmentation of ultrasonic breast lesions , 2003, IEEE Transactions on Medical Imaging.

[64]  Chunming Li,et al.  Minimization of Region-Scalable Fitting Energy for Image Segmentation , 2008, IEEE Transactions on Image Processing.

[65]  Pierre Soille,et al.  Morphological gradients , 1993, J. Electronic Imaging.

[66]  Jitendra Malik,et al.  Normalized cuts and image segmentation , 1997, Proceedings of IEEE Computer Society Conference on Computer Vision and Pattern Recognition.

[67]  Fei Xu,et al.  Unsupervised saliency estimation based on robust hypotheses , 2016, 2016 IEEE Winter Conference on Applications of Computer Vision (WACV).

[68]  Paul A. Viola,et al.  Robust Real-Time Face Detection , 2001, International Journal of Computer Vision.

[69]  Heng-Da Cheng,et al.  A fully automatic segmentation method for breast ultrasound images , 2011 .

[70]  Guillermo Sapiro,et al.  Geodesic Active Contours , 1995, International Journal of Computer Vision.

[71]  Berkman Sahiner,et al.  Three-dimensional active contour model for characterization of solid breast masses on three-dimensional ultrasound images , 2003, SPIE Medical Imaging.

[72]  Ruey-Feng Chang,et al.  Computer-Aided Multiview Tumor Detection for Automated Whole Breast Ultrasound , 2014, Ultrasonic imaging.

[73]  W. Gómez,et al.  Active Contours without Edges Applied to Breast Lesions on Ultrasound , 2010 .

[74]  Fabrice Mériaudeau,et al.  Lesion Segmentation in Breast Sonography , 2010, Digital Mammography / IWDM.

[75]  Min Xian,et al.  Fully automatic segmentation of breast ultrasound images based on breast characteristics in space and frequency domains , 2015, Pattern Recognit..

[76]  Kevin J. Parker,et al.  Multiple Resolution Bayesian Segmentation of Ultrasound Images , 1994, Other Conferences.

[77]  Kenji Suzuki,et al.  A dual-stage method for lesion segmentation on digital mammograms. , 2007, Medical physics.

[78]  Maryellen L. Giger,et al.  Automatic 3D lesion segmentation on breast ultrasound images , 2013, Medical Imaging.

[79]  Jürgen Schmidhuber,et al.  Multi-column deep neural network for traffic sign classification , 2012, Neural Networks.

[80]  M. Giger,et al.  Computerized diagnosis of breast lesions on ultrasound. , 2002, Medical physics.

[81]  R. Martí,et al.  Breast-lesion Segmentation Combining B-Mode and Elastography Ultrasound , 2016, Ultrasonic imaging.

[82]  Maryellen L. Giger,et al.  Automated seeded lesion segmentation on digital mammograms , 1998, IEEE Transactions on Medical Imaging.

[83]  Maryellen L. Giger,et al.  Level Set Segmentation of Breast Masses in Contrast-Enhanced Dedicated Breast CT and Evaluation of Stopping Criteria , 2014, Journal of Digital Imaging.

[84]  Bernhard E. Boser,et al.  A training algorithm for optimal margin classifiers , 1992, COLT '92.

[85]  Olivier Basset,et al.  Segmentation of ultrasound images--multiresolution 2D and 3D algorithm based on global and local statistics , 2003, Pattern Recognit. Lett..

[86]  P. Saint-Marc,et al.  Active contour models: overview, implementation and applications , 1990, 1990 IEEE International Conference on Systems, Man, and Cybernetics Conference Proceedings.

[87]  Vladimir Kolmogorov,et al.  What energy functions can be minimized via graph cuts? , 2002, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[88]  Xuelong Li,et al.  Optimized graph-based segmentation for ultrasound images , 2014, Neurocomputing.

[89]  Ron Kikinis,et al.  An Effective Interactive Medical Image Segmentation Method Using Fast GrowCut , 2014 .

[90]  Nam Chul Kim,et al.  3D segmentation of breast tumor in ultrasound images , 2003, SPIE Medical Imaging.

[91]  Trevor Darrell,et al.  Fully Convolutional Networks for Semantic Segmentation , 2017, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[92]  Dorin Comaniciu,et al.  Database-guided breast tumor detection and segmentation in 2D ultrasound images , 2010, Medical Imaging.

[93]  T P O'Neill,et al.  Breast ultrasound. , 1998, The Surgical clinics of North America.

[94]  Ruey-Feng Chang,et al.  3-D breast ultrasound segmentation using active contour model. , 2003, Ultrasound in medicine & biology.

[95]  Nico Karssemeijer,et al.  Large scale deep learning for computer aided detection of mammographic lesions , 2017, Medical Image Anal..

[96]  Zhihua Liu,et al.  Ultrasound breast lesion segmentation using adaptive parameters , 2014, Medical Imaging.

[97]  Steve R. Gunn,et al.  A Robust Snake Implementation; A Dual Active Contour , 1997, IEEE Trans. Pattern Anal. Mach. Intell..

[98]  Yadong Wang,et al.  A hierarchical local region-based sparse shape composition for liver segmentation in CT scans , 2016, Pattern Recognit..

[99]  Min Xian,et al.  A Fully Automatic Breast Ultrasound Image Segmentation Approach Based on Neutro-Connectedness , 2014, 2014 22nd International Conference on Pattern Recognition.

[100]  Rachid Deriche,et al.  Geodesic Active Contours and Level Sets for the Detection and Tracking of Moving Objects , 2000, IEEE Trans. Pattern Anal. Mach. Intell..

[101]  Vicent Caselles,et al.  Texture-Oriented Anisotropic Filtering and Geodesic Active Contours in Breast Tumor Ultrasound Segmentation , 2007, Journal of Mathematical Imaging and Vision.

[102]  Hiroshi Fujita,et al.  Computer-aided detection system of breast masses on ultrasound images , 2006, SPIE Medical Imaging.

[103]  Chung-Ming Chen,et al.  Cell-based graph cut for segmentation of 2D/3D sonographic breast images , 2010, 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[104]  J. Arendt Paper presented at the 10th Nordic-Baltic Conference on Biomedical Imaging: Field: A Program for Simulating Ultrasound Systems , 1996 .

[105]  Heng-Da Cheng,et al.  Segmentation of ultrasound breast images based on a neutrosophic method , 2010 .

[106]  Yasser M. Kadah,et al.  Real-time speckle reduction and coherence enhancement in ultrasound imaging via nonlinear anisotropic diffusion , 2002, IEEE Transactions on Biomedical Engineering.

[107]  Max A. Viergever,et al.  A discrete dynamic contour model , 1995, IEEE Trans. Medical Imaging.

[108]  P. Olver,et al.  Conformal curvature flows: From phase transitions to active vision , 1996, ICCV 1995.

[109]  Peng Jiang,et al.  Learning-based automatic breast tumor detection and segmentation in ultrasound images , 2012, 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI).

[110]  Roberto Manduchi,et al.  Bilateral filtering for gray and color images , 1998, Sixth International Conference on Computer Vision (IEEE Cat. No.98CH36271).

[111]  Michael Elad,et al.  On the origin of the bilateral filter and ways to improve it , 2002, IEEE Trans. Image Process..

[112]  D. Greig,et al.  Exact Maximum A Posteriori Estimation for Binary Images , 1989 .

[113]  Ke Chen,et al.  An Automatic Localization Algorithm for Ultrasound Breast Tumors Based on Human Visual Mechanism , 2017, Sensors.

[114]  Yuxuan Wang,et al.  Completely automated segmentation approach for breast ultrasound images using multiple-domain features. , 2012, Ultrasound in medicine & biology.

[115]  Moi Hoon Yap,et al.  A novel algorithm for initial lesion detection in ultrasound breast images , 2008, Journal of applied clinical medical physics.

[116]  Baba C. Vemuri,et al.  Shape Modeling with Front Propagation: A Level Set Approach , 1995, IEEE Trans. Pattern Anal. Mach. Intell..

[117]  Xianglong Tang,et al.  Fractional subpixel diffusion and fuzzy logic approach for ultrasound speckle reduction , 2010, Pattern Recognit..

[118]  Yoav Freund,et al.  A decision-theoretic generalization of on-line learning and an application to boosting , 1995, EuroCOLT.

[119]  Eran A. Edirisinghe,et al.  Fully automatic lesion boundary detection in ultrasound breast images , 2007, SPIE Medical Imaging.

[120]  Qianjin Feng,et al.  Segmentation of ultrasonic breast tumors based on homogeneous patch. , 2012, Medical physics.

[121]  Qinghua Huang,et al.  Breast ultrasound image segmentation: a survey , 2017, International Journal of Computer Assisted Radiology and Surgery.

[122]  Woo Kyung Moon,et al.  Segmentation of breast tumor in three-dimensional ultrasound images using three-dimensional discrete active contour model. , 2003, Ultrasound in medicine & biology.

[123]  Xin Jin,et al.  Mean Shift , 2017, Encyclopedia of Machine Learning and Data Mining.

[124]  Qiang Wang,et al.  Multiscale superpixel classification for tumor segmentation in breast ultrasound images , 2012, 2012 19th IEEE International Conference on Image Processing.

[125]  Jeon-Hor Chen,et al.  Whole breast lesion detection using naive bayes classifier for portable ultrasound. , 2012, Ultrasound in medicine & biology.

[126]  James C. Bezdek,et al.  Pattern Recognition with Fuzzy Objective Function Algorithms , 1981, Advanced Applications in Pattern Recognition.

[127]  M. Giger,et al.  Computerized detection and classification of cancer on breast ultrasound. , 2004, Academic radiology.

[128]  Wanqing Chen,et al.  Breast cancer in China. , 2014, The Lancet. Oncology.

[129]  Fang-Cheng Yeh,et al.  Cell-competition algorithm: a new segmentation algorithm for multiple objects with irregular boundaries in ultrasound images. , 2005, Ultrasound in medicine & biology.

[130]  Yizong Cheng,et al.  Mean Shift, Mode Seeking, and Clustering , 1995, IEEE Trans. Pattern Anal. Mach. Intell..

[131]  Richard Szeliski,et al.  A Comparative Study of Energy Minimization Methods for Markov Random Fields , 2006, ECCV.

[132]  Xianglong Tang,et al.  An Effective Approach of Lesion Segmentation Within the Breast Ultrasound Image Based on the Cellular Automata Principle , 2011, Journal of Digital Imaging.

[133]  Leo Grady,et al.  Random Walks for Image Segmentation , 2006, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[134]  Dar-Ren Chen,et al.  Watershed segmentation for breast tumor in 2-D sonography. , 2004, Ultrasound in medicine & biology.

[135]  Alex M. Andrew,et al.  Level Set Methods and Fast Marching Methods: Evolving Interfaces in Computational Geometry, Fluid Mechanics, Computer Vision, and Materials Science (2nd edition) , 2000 .

[136]  John von Neumann,et al.  Theory Of Self Reproducing Automata , 1967 .

[137]  Chunming Li,et al.  Distance Regularized Level Set Evolution and Its Application to Image Segmentation , 2010, IEEE Transactions on Image Processing.

[138]  Hiroshi Fujita,et al.  Development of a fully automatic scheme for detection of masses in whole breast ultrasound images. , 2007, Medical physics.

[139]  Xianglong Tang,et al.  Fully automatic and segmentation-robust classification of breast tumors based on local texture analysis of ultrasound images , 2010, Pattern Recognit..

[140]  Dimitris N. Metaxas,et al.  Automatic boundary extraction of ultrasonic breast lesions , 2002, Proceedings IEEE International Symposium on Biomedical Imaging.

[141]  Demetri Terzopoulos,et al.  Snakes: Active contour models , 2004, International Journal of Computer Vision.

[142]  Brian Kingsbury,et al.  New types of deep neural network learning for speech recognition and related applications: an overview , 2013, 2013 IEEE International Conference on Acoustics, Speech and Signal Processing.

[143]  Henry Horng-Shing Lu,et al.  Cell-based dual snake model: a new approach to extracting highly winding boundaries in the ultrasound images. , 2002, Ultrasound in medicine & biology.

[144]  Heng-Da Cheng,et al.  Novel approaches to image segmentation based on neutrosophic logic , 2012 .

[145]  Pascal Fua,et al.  SLIC Superpixels Compared to State-of-the-Art Superpixel Methods , 2012, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[146]  Yuanyuan Wang,et al.  A phase-based active contour model for segmentation of breast ultrasound images , 2013, 2013 6th International Conference on Biomedical Engineering and Informatics.

[147]  Karen Drukker,et al.  Computerized detection and classification of lesions on breast ultrasound , 2003, SPIE Medical Imaging.

[148]  Maryellen L. Giger,et al.  Segmentation of breast masses on dedicated breast computed tomography and three-dimensional breast ultrasound images , 2014, Journal of medical imaging.

[149]  Lorenzo Leija,et al.  Segmentation of Breast Nodules on Ultrasonographic Images Based on Marke d-Controlled Watershed Transform , 2010, Computación y Sistemas.

[150]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.

[151]  Lubomir M. Hadjiiski,et al.  Computerized characterization of breast masses on three-dimensional ultrasound volumes. , 2004, Medical physics.

[152]  J. M. Hammersley,et al.  Markov fields on finite graphs and lattices , 1971 .

[153]  Yan Xu,et al.  A modified spatial fuzzy clustering method based on texture analysis for ultrasound image segmentation , 2009, 2009 IEEE International Symposium on Industrial Electronics.

[154]  Dar-Ren Chen,et al.  Automatic Contouring for Breast Tumors in 2-D Sonography , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[155]  Mohammad I. Daoud,et al.  Accurate Segmentation of Breast Tumors in Ultrasound Images Using a Custom-Made Active Contour Model and Signal-to-Noise Ratio Variations , 2012, 2012 Eighth International Conference on Signal Image Technology and Internet Based Systems.

[156]  Karen Drukker,et al.  Computerized analysis of sonograms for the detection of breast lesions , 2002, SPIE Medical Imaging.

[157]  Demetri Terzopoulos,et al.  On Matching Deformable Models to Images , 1987, Topical Meeting on Machine Vision.

[158]  Vladimir Kolmogorov,et al.  An experimental comparison of min-cut/max- flow algorithms for energy minimization in vision , 2001, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[159]  Xianglong Tang,et al.  Automated segmentation of ultrasonic breast lesions using statistical texture classification and active contour based on probability distance. , 2009, Ultrasound in medicine & biology.

[160]  Ruey-Feng Chang,et al.  Multi-Dimensional Tumor Detection in Automated Whole Breast Ultrasound Using Topographic Watershed , 2014, IEEE Transactions on Medical Imaging.

[161]  Zhimin Huo,et al.  Automated segmentation of breast lesions in ultrasound images , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[162]  Yadong Wang,et al.  Low‐rank and sparse decomposition based shape model and probabilistic atlas for automatic pathological organ segmentation , 2017, Medical Image Anal..

[163]  Heung-Il Suk,et al.  Deep Learning in Medical Image Analysis. , 2017, Annual review of biomedical engineering.

[164]  Nam Chul Kim,et al.  RD-Based Seeded Region Growing for Extraction of Breast Tumor in an Ultrasound Volume , 2005, CIS.

[165]  Fei Xu,et al.  EISeg: Effective interactive segmentation , 2016, 2016 23rd International Conference on Pattern Recognition (ICPR).

[166]  Jie-Zhi Cheng,et al.  Cell-based two-region competition algorithm with a map framework for boundary delineation of a series of 2D ultrasound images. , 2007, Ultrasound in medicine & biology.

[167]  Feiping Nie,et al.  TurboPixel Segmentation Using Eigen-Images , 2010, IEEE Transactions on Image Processing.

[168]  Tony F. Chan,et al.  Active contours without edges , 2001, IEEE Trans. Image Process..

[169]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[170]  M. Giger,et al.  Automatic segmentation of breast lesions on ultrasound. , 2001, Medical physics.

[171]  Douglas L. Jones,et al.  Detection of lines and boundaries in speckle images-application to medical ultrasound , 1999, IEEE Transactions on Medical Imaging.

[172]  David W. Hosmer,et al.  Applied Logistic Regression , 1991 .

[173]  Chen Yintao,et al.  Adaptive expanding B-snake model for extracting ultrasound breast lump boundary , 2001, The Seventh Australian and New Zealand Intelligent Information Systems Conference, 2001.

[174]  Michael Brady,et al.  Segmentation of ultrasound B-mode images with intensity inhomogeneity correction , 2002, IEEE Transactions on Medical Imaging.

[175]  J. Jensen,et al.  Calculation of pressure fields from arbitrarily shaped, apodized, and excited ultrasound transducers , 1992, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[176]  M. Giger,et al.  Computerized lesion detection on breast ultrasound. , 2002, Medical physics.

[177]  Ingemar J. Cox,et al.  A maximum-flow formulation of the N-camera stereo correspondence problem , 1998, Sixth International Conference on Computer Vision (IEEE Cat. No.98CH36271).

[178]  Vladimir Vapnik,et al.  Statistical learning theory , 1998 .

[179]  J. Besag On the Statistical Analysis of Dirty Pictures , 1986 .

[180]  Hamid R. Tizhoosh,et al.  Segmentation of Breast Ultrasound Images Using Neural Networks , 2011, EANN/AIAI.

[181]  H. D. Cheng,et al.  A novel segmentation method for breast ultrasound images based on neutrosophic l-means clustering. , 2012, Medical physics.