A Review on Statistical Importance and Biomarkers Identification in Hashimoto Thyroiditis Disease

Alter in biological media can be identified using biomarkers. For both pathogenesis and epidemiology, the biomarker plays an important role. Antecedent biomarkers are partially associated with the etiology. With the use of computational techniques for statistical analysis, better results can be possible. Irradiation, selenium, vitamin D, chemical issues like halogenated organochlorines, transthyretin are biomarkers of exposure in the thyroid disorder, where these biomarkers may or may not involve directly in the etiology. Biomarkers of thyroid disease include image-guided diagnostic tests like ultrasound and sonogram. Invasive diagnostic tests such as ultrasound-guided FNA, biopsy, hormone test, and antibody test are putative biomarkers of thyroid disorder. TSH test, Thyroperoxidase antibodies (TPOAb), Thyroglobulin Antibodies (TgAb), and Thyroid-stimulating hormone receptor antibodies (TRAb) are hormone and antibody test plays a significant role in the diagnosis of Hashimoto Thyroiditis (HT). This study explores the knowledge of Hashimoto thyroiditis and delineates novel biomarkers associated with it.