Flow cytometry: an alternative method for direct quantification of antigens adsorbed to aluminum hydroxide adjuvant.

[1]  M. Mbow,et al.  Alum's adjuvant action: grease is the word , 2011, Nature Medicine.

[2]  Theodore W Randolph,et al.  Flow cytometry: a promising technique for the study of silicone oil-induced particulate formation in protein formulations. , 2011, Analytical biochemistry.

[3]  Dexiang Chen,et al.  Vaccines with aluminum-containing adjuvants: optimizing vaccine efficacy and thermal stability. , 2011, Journal of pharmaceutical sciences.

[4]  R. Rappuoli,et al.  Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans , 2010, Proceedings of the National Academy of Sciences.

[5]  A. Saul,et al.  Use of o-phthalaldehyde assay to determine protein contents of Alhydrogel-based vaccines. , 2009, Vaccine.

[6]  E. Gebregeorgis,et al.  Development of a Direct Alhydrogel Formulation Immunoassay (DAFIA). , 2009, Journal of immunological methods.

[7]  C. Goso,et al.  Forces determining the adsorption of a monoclonal antibody onto an aluminium hydroxide adjuvant: influence of interstitial fluid components. , 2009, Vaccine.

[8]  S. Jacobsen,et al.  Determination of Adsorbed Protein Concentration in Aluminum Hydroxide Suspensions by Near-Infrared Transmittance Spectroscopy , 2008, Applied spectroscopy.

[9]  Henk C. Hoogsteden,et al.  Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells , 2008, The Journal of experimental medicine.

[10]  S. Hem,et al.  Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation , 2007, Expert review of vaccines.

[11]  Anna Sokolovska,et al.  Relationship between the strength of antigen adsorption to an aluminum-containing adjuvant and the immune response. , 2007, Vaccine.

[12]  H. HogenEsch,et al.  Potentiation of the immune response to non-adsorbed antigens by aluminum-containing adjuvants. , 2007, Vaccine.

[13]  S. Jacobsen,et al.  The structural stability of protein antigens adsorbed by aluminium hydroxide in comparison to the antigens in solutions , 2007 .

[14]  C. Hutcheon,et al.  Physiochemical and functional characterization of antigen proteins eluted from aluminum hydroxide adjuvant. , 2006, Vaccine.

[15]  K. Foster,et al.  Association Between Immunogenicity and Adsorption of a Recombinant Streptococcus pneumoniae Vaccine Antigen by an Aluminum Adjuvant , 2006, Human vaccines.

[16]  L. Peek,et al.  Effects of Adsorption to Aluminum Salt Adjuvants on the Structure and Stability of Model Protein Antigens* , 2005, Journal of Biological Chemistry.

[17]  J. Paul Robinson,et al.  Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro. , 2005, Vaccine.

[18]  R. Rappuoli,et al.  Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells , 2004, Molecular microbiology.

[19]  R. Rappuoli,et al.  Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity. , 2003, The Journal of infectious diseases.

[20]  A. Ducrest,et al.  Detection of promoter activity by flow cytometric analysis of GFP reporter expression. , 2002, Nucleic acids research.

[21]  R. Rappuoli,et al.  NadA, a Novel Vaccine Candidate of Neisseria meningitidis , 2002, The Journal of experimental medicine.

[22]  W. Matheis,et al.  The role of the adsorption process for production and control combined adsorbed vaccines. , 2001, Vaccine.

[23]  Z. Darżynkiewicz,et al.  Flow cytometry in analysis of cell cycle and apoptosis. , 2001, Seminars in hematology.

[24]  Gupta,et al.  Aluminum compounds as vaccine adjuvants. , 1998, Advanced drug delivery reviews.

[25]  J. White,et al.  Solubilization of aluminum-containing adjuvants by constituents of interstitial fluid. , 1991, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

[26]  J. Katz,et al.  In vitro assessment of viral antigen content in inactivated aluminum hydroxide adjuvanted vaccines. , 1989, Journal of virological methods.

[27]  G. Zlabinger,et al.  Modulation of the human immune response by the non-toxic and non-pyrogenic adjuvant aluminium hydroxide: effect on antigen uptake and antigen presentation. , 1985, Clinical and experimental immunology.

[28]  W. T. Harrison.  Some Observations on the Use of Alum Precipitated Diphtheria Toxoid. , 1935, American journal of public health and the nation's health.

[29]  A. Glenny,et al.  Rate of Disappearance of Diphtheria Toxoid injected into Rabbits and Guinea-Pigs: Toxoid precipitated with Alum. , 1931 .