Global Climate and Infectious Disease: The Cholera Paradigm*

The origin of cholera has been elusive, even though scientific evidence clearly shows it is a waterborne disease. However, standard bacteriological procedures for isolation of the cholera vibrio from environmental samples, including water, between epidemics generally were unsuccessful. Vibrio cholerae, a marine vibrio, requiring salt for growth, enters into a dormant, viable but nonculturable stage when conditions are unfavorable for growth and reproduction. The association of Vibrio cholerae with plankton, notably copepods, provides further evidence for the environmental origin of cholera, as well as an explanation for the sporadic and erratic occurrence of cholera epidemics. On a global scale, cholera epidemics can now be related to climate and climatic events, such as El Niño, as well as the global distribution of the plankton host. Remote sensing, with the use of satellite imagery, offers the potential for predicting conditions conducive to cholera outbreaks or epidemics.

[1]  R. Colwell,et al.  Serogroup conversion of Vibrio cholerae. , 1995, Canadian journal of microbiology.

[2]  R. Colwell,et al.  Ecology of Vibrio parahaemolyticus in Chesapeake Bay , 1973, Journal of bacteriology.

[3]  R. Sack,et al.  Advances in Research on Cholera and Related Diarrheas , 1983, New Perspectives in Clinical Microbiology.

[4]  Rita R. Colwell,et al.  Fate of Vibrio cholerae O1 in seawater microcosms , 1996 .

[5]  S. Morse,et al.  Factors in the emergence of infectious diseases. , 1995, Emerging infectious diseases.

[6]  R. Colwell.  Polyphasic Taxonomy of the Genus Vibrio: Numerical Taxonomy of Vibrio cholerae, Vibrio parahaemolyticus, and Related Vibrio Species , 1970, Journal of bacteriology.

[7]  J. Patz,et al.  Global climate change and emerging infectious diseases. , 1996, JAMA.

[8]  R. Colwell,et al.  A simple filtration method to remove plankton-associated Vibrio cholerae in raw water supplies in developing countries , 1996, Applied and environmental microbiology.

[9]  J. Oliver,et al.  Distribution of Vibrio vulnificus and Other Lactose-Fermenting Vibrios in the Marine Environment , 1983, Applied and environmental microbiology.

[10]  D. A. Okun.  From Cholera to Cancer to Cryptosporidiosis , 1996 .

[11]  R. Glass,et al.  Seroepidemiological studies of El Tor cholera in Bangladesh: association of serum antibody levels with protection. , 1985, The Journal of infectious diseases.

[12]  R. Sack,et al.  Emergence of a new epidemic strain of Vibrio cholerae in Bangladesh. An epidemiological study. , 1994, Tropical and geographical medicine.

[13]  F. Mooi,et al.  Genesis of the novel epidemic Vibrio cholerae O139 strain: evidence for horizontal transfer of genes involved in polysaccharide synthesis. , 1995, The EMBO journal.

[14]  R. Colwell,et al.  Detection of luciferase gene sequence in nonluminescent Vibrio cholerae by colony hybridization and polymerase chain reaction , 1991, Applied and environmental microbiology.

[15]  P. Reeves,et al.  The sixth and seventh cholera pandemics are due to independent clones separately derived from environmental, nontoxigenic, non-O1 Vibrio cholerae , 1995, Journal of bacteriology.

[16]  C. Proby,et al.  New broad-spectrum sunscreen for polymorphic light eruption , 1993, The Lancet.

[17]  Amit Pal,et al.  Emergence of novel strain of Vibrio cholerae with epidemic potential in southern and eastern India , 1993, The Lancet.

[18]  M. S. Islam,et al.  Attachment of toxigenic Vibrio cholerae 01 to various freshwater plants and survival with a filamentous green alga, Rhizoclonium fontanum. , 1989, The Journal of tropical medicine and hygiene.

[19]  J. Brock,et al.  Interannual variability in phytoplankton blooms observed in the northwestern Arabian Sea during the southwest monsoon , 1992 .

[20]  M. Hood,et al.  Survival of Vibrio cholerae and Escherichia coli in estuarine waters and sediments , 1982, Applied and environmental microbiology.

[21]  S. Faruque,et al.  Clonal relationships among classical Vibrio cholerae O1 strains isolated between 1961 and 1992 in Bangladesh , 1993, Journal of clinical microbiology.

[22]  Ø. Olsvik,et al.  Vibrio cholerae and cholera : molecular to global perspectives , 1994 .

[23]  R. Colwell,et al.  Ecology, serology, and enterotoxin production of Vibrio cholerae in Chesapeake Bay , 1979, Applied and environmental microbiology.

[24]  K. Kogure,et al.  Enumerations of Vibrio cholerae in Aquatic Environments by MPN-16S rRNA Hybridization Method , 1992 .

[25]  R. Colwell,et al.  Enumeration of Vibrio cholerae O1 in Bangladesh waters by fluorescent-antibody direct viable count , 1987, Applied and environmental microbiology.

[26]  R. Hill,et al.  Decrease in culturability of Vibrio cholerae caused by glucose , 1995, Applied and environmental microbiology.

[27]  ジャパンタイムズ.  The Japan Times , 1934 .

[28]  W. Mosley,et al.  Endemic cholera in rural East Pakistan. , 1969, American journal of epidemiology.

[29]  R. Colwell,et al.  Influence of salinity and organic nutrient concentration on survival and growth of Vibrio cholerae in aquatic microcosms , 1982, Applied and environmental microbiology.

[30]  R. Colwell,et al.  A novel kit for rapid detection of Vibrio cholerae O1 , 1994, Journal of clinical microbiology.

[31]  M. Levine,et al.  Viable but non-culturable Vibrio cholerae O1 revert to a cultivable state in the human intestine , 1996, World journal of microbiology & biotechnology.

[32]  R. Colwell,et al.  An indirect fluoresent antibody staining procedure for detection of Vibrio cholerae serovar 01 cells in aquatic environmental samples , 1984 .

[33]  Timothy J. Hoar,et al.  The 1990–1995 El Niño‐Southern Oscillation Event: Longest on Record , 1996 .

[34]  Y. Takeda,et al.  Spread of Vibrio cholerae O139 Bengal in India. , 1994, The Journal of infectious diseases.

[35]  M. S. Islam,et al.  Survival of toxigenic Vibrio cholerae O1 with a common duckweed, Lemna minor, in artificial aquatic ecosystems. , 1990, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[36]  S. Hawkins,et al.  Seventy years' observations of changes in distribution and abundance of zooplankton and intertidal organisms in the western English Channel in relation to rising sea temperature , 1995 .

[37]  V. DiRita.  Vibrio cholerae and cholera: molecular to global perspectives , 1995 .

[38]  Kaviraj Kunjalal Bhishagratna.  An English translation of the Sushruta Samhita : based on original Sanskrit text , 1907 .

[39]  R. Colwell,et al.  Viability and virulençe of Escherichia coli suspended by membrane chamber in semitropical ocean water , 1986 .

[40]  R. Colwell,et al.  Coexistence of Vibrio cholerae 01 and 0139 Bengal in plankton in Bangladesh , 1995, The Lancet.

[41]  R. Sack,et al.  Progressive Changes of Vibrio Serotypes in Germ-free Mice Infected with Vibrio cholerae , 1969, Journal of bacteriology.

[42]  R. Waldman,et al.  Cholera in Africa: lessons on transmission and control for Latin America , 1991, The Lancet.

[43]  L. Mata,et al.  Cholera El Tor in Latin America, 1991‐1993 a , 1994, Annals of the New York Academy of Sciences.

[44]  R. Hendrickse.  Acute enteric infections in children - new prospects for treatment and prevention , 1982 .

[45]  J. Kaper,et al.  Cloning and sequence of a region encoding a surface polysaccharide of Vibrio cholerae O139 and characterization of the insertion site in the chromosome of Vibrio cholerae O1 , 1996, Molecular microbiology.

[46]  Anwarul Huq,et al.  Uptake of Vibrio cholerae Biotype eltor from Contaminated Water by Water Hyacinth (Eichornia crassipes) , 1981, Applied and environmental microbiology.

[47]  竹田 美文,et al.  Vibrio cholerae and cholera , 1988 .

[48]  R. Colwell,et al.  The Vibrio cholerae O139 serogroup antigen includes an O-antigen capsule and lipopolysaccharide virulence determinants. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[49]  R. Colwell,et al.  Production and cross-reactivity patterns of a panel of high affinity monoclonal antibodies to Vibrio cholerae O139 Bengal. , 1994, FEMS immunology and medical microbiology.

[50]  M U Khan,et al.  Endemic cholera in rural Bangladesh, 1966-1980. , 1982, American journal of epidemiology.

[51]  A. Takade,et al.  Morphology of the viable but nonculturable Vibrio cholerae as determined by the freeze fixation technique. , 1994, FEMS microbiology letters.

[52]  R. Colwell,et al.  Detection of Vibrio cholerae O1 in the aquatic environment by fluorescent-monoclonal antibody and culture methods , 1990, Applied and environmental microbiology.