PPARγ-dependent pathway in the growth-inhibitory effects of K562 cells by carotenoids in combination with rosiglitazone.

[1]  M. Hu,et al.  Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway. , 2012, The Journal of nutritional biochemistry.

[2]  M. Schulze,et al.  Critical review: vegetables and fruit in the prevention of chronic diseases , 2012, European Journal of Nutrition.

[3]  Kenneth R. Jones,et al.  Physiological responses to acute psychological stress are reduced by the PPARγ agonist rosiglitazone. , 2012, Endocrinology.

[4]  Chih-min Yang,et al.  Lycopene inhibits the proliferation of androgen-dependent human prostate tumor cells through activation of PPARγ-LXRα-ABCA1 pathway. , 2012, The Journal of nutritional biochemistry.

[5]  Z. Rosenwaks,et al.  Rosiglitazone and Pioglitazone Alter Aromatase Kinetic Properties in Human Granulosa Cells , 2011, PPAR research.

[6]  P. Palozza,et al.  Lycopene regulation of cholesterol synthesis and efflux in human macrophages. , 2011, The Journal of nutritional biochemistry.

[7]  Wen-en Zhao,et al.  Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells. , 2011, Archives of biochemistry and biophysics.

[8]  V. Toscano,et al.  Rosiglitazone induces autophagy in H295R and cell cycle deregulation in SW13 adrenocortical cancer cells. , 2011, Experimental cell research.

[9]  J. Keijer,et al.  Beta-Carotene Reduces Body Adiposity of Mice via BCMO1 , 2011, PloS one.

[10]  J. Woodside,et al.  Biomarkers of Fruit and Vegetable Intake in Human Intervention Studies: A Systematic Review , 2011, Critical reviews in food science and nutrition.

[11]  P. Palozza,et al.  Lycopene Inhibits NF-kB-Mediated IL-8 Expression and Changes Redox and PPARγ Signalling in Cigarette Smoke–Stimulated Macrophages , 2011, PloS one.

[12]  T. Xu,et al.  Rosiglitazone and retinoic acid inhibit proliferation and induce apoptosis in the HCT-15 human colorectal cancer cell line. , 2011, Experimental and therapeutic medicine.

[13]  P. Palozza,et al.  Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression. , 2011, The Journal of nutritional biochemistry.

[14]  N. Miyoshi,et al.  β-Carotene accumulation in 3T3-L1 adipocytes inhibits the elevation of reactive oxygen species and the suppression of genes related to insulin sensitivity induced by tumor necrosis factor-α. , 2010, Nutrition.

[15]  J. Hoffmann,et al.  Mistletoe lectin‐I augments antiproliferative effects of the PPARγ agonist rosiglitazone on human malignant melanoma cells , 2010, Phytotherapy research : PTR.

[16]  J. Roman,et al.  Anticancer actions of PPARγ ligands: Current state and future perspectives in human lung cancer. , 2010, World journal of biological chemistry.

[17]  T. Kawada,et al.  Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation. , 2009, Biochemical and biophysical research communications.

[18]  G. Colditz,et al.  Circulating carotenoids, mammographic density, and subsequent risk of breast cancer. , 2009, Cancer research.

[19]  S. Belinsky,et al.  Rosiglitazone prevents the progression of preinvasive lung cancer in a murine model. , 2007, Carcinogenesis.

[20]  Yong Zhang,et al.  Peroxisome Proliferator-Activated Receptor γ (PPAR-γ) Agonist Rosiglitazone (RGZ) Inhibits HL-60 Cell Growth by Induction of Apoptosis , 2009 .

[21]  P. Parsons,et al.  PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells. , 2009, The international journal of biochemistry & cell biology.

[22]  T. Hu,et al.  Peroxisome Proliferator-Activated Receptor-γ Agonist Rosiglitazone– Induced Apoptosis in Leukemia K562 Cells and Its Mechanisms of Action , 2009, International journal of toxicology.

[23]  F. Ondrey,et al.  Peroxisome Proliferator-Activated Receptor γ Pathway Targeting in Carcinogenesis: Implications for Chemoprevention , 2009, Clinical Cancer Research.

[24]  I. Barshack,et al.  A 9-cis β-Carotene–Enriched Diet Inhibits Atherogenesis and Fatty Liver Formation in LDL Receptor Knockout Mice , 2008 .

[25]  K. Vareli,et al.  PPARγ: The Portrait of a Target Ally to Cancer Chemopreventive Agents , 2008, PPAR research.

[26]  J. Herman,et al.  Carotenoids and the risk of developing lung cancer: a systematic review. , 2008, The American journal of clinical nutrition.

[27]  P. Palozza,et al.  Interplay of carotenoids with cigarette smoking: implications in lung cancer. , 2008, Current medicinal chemistry.

[28]  J. Liao,et al.  Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. , 2008, The Journal of nutrition.

[29]  K. Vareli,et al.  ReviewArticle PPARγ: The Portrait of a Target Ally to Cancer Chemopreventive Agents , 2008 .

[30]  Wen-en Zhao,et al.  β-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor γ expression and reactive oxygen species production in MCF-7 cancer cells , 2007 .

[31]  J. Roman,et al.  Peroxisome proliferator-activated receptor &ggr;: a novel target for cancer therapeutics? , 2007, Anti-cancer drugs.

[32]  R. Russell,et al.  β‐Cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non‐small‐cell lung cancer cells and up‐regulates retinoic acid receptor β expression , 2006 .

[33]  T. Mok,et al.  Apoptosis induced by troglitazone is both peroxisome proliferator‐activated receptor‐γ‐ and ERK‐dependent in human non‐small lung cancer cells , 2006, Journal of cellular physiology.

[34]  T. Horie,et al.  Pioglitazone inhibits the growth of human leukemia cell lines and primary leukemia cells while sparing normal hematopoietic stem cells. , 2006, International journal of oncology.

[35]  Manabu T. Nakamura,et al.  Dietary Lycopene Downregulates Carotenoid 15,15′-Monooxygenase and PPAR-γ in Selected Rat Tissues , 2006 .

[36]  J. Roman,et al.  Rosiglitazone suppresses human lung carcinoma cell growth through PPARγ-dependent and PPARγ-independent signal pathways , 2006, Molecular Cancer Therapeutics.

[37]  Michael Lehrke,et al.  The Many Faces of PPARγ , 2005, Cell.

[38]  F. Clavel-Chapelon,et al.  Dual Association of beta-carotene with risk of tobacco-related cancers in a cohort of French women. , 2005, Journal of the National Cancer Institute.

[39]  C. Grommes,et al.  Antineoplastic effects of peroxisome proliferatoractivated receptor γ agonists , 2004 .

[40]  P. Fisher,et al.  Up-regulation of p21 Gene Expression by Peroxisome Proliferator-Activated Receptor γ in Human Lung Carcinoma Cells , 2004, Clinical Cancer Research.

[41]  H. Koeffler.  Peroxisome proliferator-activated receptor γ and cancers , 2003 .

[42]  É. Szabó,et al.  Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

[43]  Y. Matsuzawa,et al.  Peroxisome proliferator-activated receptor gamma reduces the growth rate of pancreatic cancer cells through the reduction of cyclin D1. , 2002, Life sciences.

[44]  P. Fisher,et al.  Role of cyclin-dependent kinases and their inhibitors in cellular differentiation and development. , 1998, Current topics in microbiology and immunology.