Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats.
暂无分享,去创建一个
M. Alves | P. Oliveira | S. Correia | P. Moreira | A. Duarte | S. Cardoso | M. S. Santos | Renato X Santos | C. Carvalho | R. Santos | Maria S. Santos | M. Alves
[1] S. Correia,et al. Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance , 2013, Neurobiology of Disease.
[2] S. Hébert,et al. Deregulation of Protein Phosphatase 2A and Hyperphosphorylation of τ Protein Following Onset of Diabetes in NOD Mice , 2013, Diabetes.
[3] S. Correia,et al. Alzheimer disease as a vascular disorder: Where do mitochondria fit? , 2012, Experimental Gerontology.
[4] M. Haller,et al. Type 1 diabetes: current concepts in epidemiology, pathophysiology, clinical care, and research. , 2012, Current problems in pediatric and adolescent health care.
[5] T. Abbruscato,et al. The Role of Glucose Transporters in Brain Disease: Diabetes and Alzheimer’s Disease , 2012, International journal of molecular sciences.
[6] M. Feany,et al. Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo , 2012, Neuron.
[7] P. Reddy,et al. Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage. , 2012, Human molecular genetics.
[8] Robert Clarke,et al. Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .
[9] J. Falcón-Pérez,et al. Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles , 2012, FEBS letters.
[10] A. Peters,et al. Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain. , 2011, The American journal of pathology.
[11] O. Shirihai,et al. Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus , 2011, Circulation.
[12] Guogang Xu,et al. Effects of streptozotocin-induced diabetes on tau phosphorylation in the rat brain , 2011, Brain Research.
[13] S. Fuke,et al. Regional variation in mitochondrial DNA copy number in mouse brain. , 2011, Biochimica et biophysica acta.
[14] P. Moreira,et al. Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. , 2010, Biochimica et biophysica acta.
[15] R. Pautler,et al. Hyperglycemia Induces Oxidative Stress and Impairs Axonal Transport Rates in Mice , 2010, PloS one.
[16] G. Perry,et al. Autophagy in Alzheimer’s disease , 2010, Expert review of neurotherapeutics.
[17] George Perry,et al. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. , 2010, International journal of clinical and experimental pathology.
[18] E. Masliah,et al. Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice , 2010, Experimental Neurology.
[19] S. Correia,et al. Targeting autophagy in the brain: a promising approach? , 2010, Central nervous system agents in medicinal chemistry.
[20] E. Feldman,et al. Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy , 2010, Acta Neuropathologica.
[21] Arlan Richardson,et al. Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. , 2010, The Journal of biological chemistry.
[22] G. Perkins,et al. Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1. , 2009, Biochimica et biophysica acta.
[23] Hui-yu Liu,et al. Prolonged Exposure to Insulin Suppresses Mitochondrial Production in Primary Hepatocytes* , 2009, Journal of Biological Chemistry.
[24] Gerard Manning,et al. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. , 2009, Cancer research.
[25] D. Zochodne,et al. Intranasal Insulin Ameliorates Experimental Diabetic Neuropathy , 2009, Diabetes.
[26] D. Cooke,et al. Type 1 diabetes mellitus in pediatrics. , 2008, Pediatrics in review.
[27] C. Oliveira,et al. Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression. , 2008, Biochimica et biophysica acta.
[28] R. Scarpulla. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. , 2008, Physiological reviews.
[29] I. Deary,et al. Cognition and diabetes: a lifespan perspective , 2008, The Lancet Neurology.
[30] J. Luchsinger,et al. Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms , 2007, The Journal of Neuroscience.
[31] A. Zmijewska,et al. Tau Is Hyperphosphorylated at Multiple Sites in Mouse Brain In Vivo After Streptozotocin-Induced Insulin Deficiency , 2006, Diabetes.
[32] R. Scarpulla,et al. Nuclear control of respiratory gene expression in mammalian cells , 2006, Journal of cellular biochemistry.
[33] P. Moreira,et al. Insulin protects against amyloid β-peptide toxicity in brain mitochondria of diabetic rats , 2005, Neurobiology of Disease.
[34] N. Krishna,et al. Sequestosome 1/p62 Is a Polyubiquitin Chain Binding Protein Involved in Ubiquitin Proteasome Degradation , 2004, Molecular and Cellular Biology.
[35] D. Zochodne,et al. Direct insulin signaling of neurons reverses diabetic neuropathy. , 2004, Diabetes.
[36] Patrick R Hof,et al. Diet‐induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[37] D. Alkon,et al. Insulin and the insulin receptor in experimental models of learning and memory. , 2004, European journal of pharmacology.
[38] F. Benfenati,et al. Synaptophysin: leading actor or walk-on role in synaptic vesicle exocytosis? , 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.
[39] P. Moreira,et al. Amyloid β-Peptide Promotes Permeability Transition Pore in Brain Mitochondria , 2001 .
[40] J. Kuret,et al. C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease. , 2000, Journal of cell science.
[41] M. Gurney,et al. Tau Phosphorylation at Serine 396 and Serine 404 by Human Recombinant Tau Protein Kinase II Inhibits Tau's Ability to Promote Microtubule Assembly* , 2000, The Journal of Biological Chemistry.
[42] V. Mootha,et al. Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1 , 1999, Cell.
[43] R. Roth,et al. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[44] V. Lee,et al. Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons* , 1997, The Journal of Biological Chemistry.
[45] S. Doré,et al. Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[46] R. Scarpulla,et al. Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[47] T. Mohri,et al. Toxic effect of a β-amyloid peptide (β22–35) on the hippocampal neuron and its prevention , 1993, Neuroscience Letters.
[48] P. Reichard,et al. The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus. , 1993, The New England journal of medicine.
[49] R. Jope,et al. Proteolysis of tau by calpain. , 1989, Biochemical and biophysical research communications.
[50] A. Drash,et al. Cognitive deficits in adolescents who developed diabetes early in life. , 1985, Pediatrics.
[51] G. Azzone,et al. Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes. , 1981, The Journal of biological chemistry.
[52] B Chance,et al. Hydroperoxide metabolism in mammalian organs. , 1979, Physiological reviews.
[53] N. Kamo,et al. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state , 1979, The Journal of Membrane Biology.
[54] K. Kurihara,et al. Selective electrode for dibenzyl dimethyl ammonium cation as indicator of the membrane potential in biological systems. , 1977, Biochimica et biophysica acta.
[55] A. Gornall,et al. Determination of serum proteins by means of the biuret reaction. , 1949, The Journal of biological chemistry.
[56] C. Gong,et al. Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes. , 2013, Journal of Alzheimer's disease : JAD.
[57] P. Oliveira,et al. Evaluation of respiration with clark type electrode in isolated mitochondria and permeabilized animal cells. , 2012, Methods in molecular biology.
[58] G. Perry,et al. Mitochondria: a therapeutic target in neurodegeneration. , 2010, Biochimica et biophysica acta.
[59] Xiongwei Zhu,et al. Insulin is a two-edged knife on the brain. , 2009, Journal of Alzheimer's disease : JAD.
[60] A. Quattrini,et al. Diabetes regulates mitochondrial biogenesis and fission in mouse neurons , 2009, Diabetologia.
[61] Jian-Zhi Wang,et al. Inhibition of autophagy causes tau proteolysis by activating calpain in rat brain. , 2009, Journal of Alzheimer's disease : JAD.
[62] Luca Scorrano,et al. A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis. , 2002, Developmental cell.
[63] R. Hawkins,et al. Brain energy metabolism in streptozotocin-diabetes. , 1988, The Biochemical journal.
[64] R. Estabrook. [7] Mitochondrial respiratory control and the polarographic measurement of ADP : O ratios , 1967 .
[65] B CHANCE,et al. The respiratory chain and oxidative phosphorylation. , 1956, Advances in enzymology and related subjects of biochemistry.