CD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinases.

[1]  A. Shaw,et al.  Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[2]  J. Ashwell,et al.  ZAPping the T-cell receptor , 1993, Current Biology.

[3]  A. Weiss,et al.  CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. , 1993, The EMBO journal.

[4]  D. Alexander,et al.  CD45 tyrosine phosphatase‐activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx. , 1992, The EMBO journal.

[5]  Arthur Weiss,et al.  ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain , 1992, Cell.

[6]  A. Alcover,et al.  Both T cell receptor (TcR)‐CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR‐CD3‐independent and CD45‐dependent activation of p56lck , 1992, European journal of immunology.

[7]  J. Fargnoli,et al.  Activation of tyrosine kinase p60fyn following T cell antigen receptor cross-linking. , 1992, The Journal of biological chemistry.

[8]  P. Stein,et al.  pp59 fyn mutant mice display differential signaling in thymocytes and peripheral T cells , 1992, Cell.

[9]  R. Perlmutter,et al.  Defective T cell receptor signaling in mice lacking the thymic isoform of p59 fyn , 1992, Cell.

[10]  C. June,et al.  The CD45 tyrosine phosphatase regulates phosphotyrosine homeostasis and its loss reveals a novel pattern of late T cell receptor-induced Ca2+ oscillations , 1992, The Journal of experimental medicine.

[11]  Arthur Weiss,et al.  Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor , 1992, Cell.

[12]  J. Partanen,et al.  The human p50csk tyrosine kinase phosphorylates p56lck at Tyr‐505 and down regulates its catalytic activity. , 1992, The EMBO journal.

[13]  A. Kong,et al.  A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor. , 1992, The Journal of biological chemistry.

[14]  A. Wakeham,et al.  Profound block in thymocyte development in mice lacking p56lck , 1992, Nature.

[15]  T. Mustelin,et al.  Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase , 1992, European Journal of Immunology.

[16]  S. Kanner,et al.  Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase , 1992, European journal of immunology.

[17]  J. Bolen,et al.  Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases , 1992, Nature.

[18]  I. Trowbridge.  CD45. A prototype for transmembrane protein tyrosine phosphatases. , 1991, The Journal of biological chemistry.

[19]  Arthur Weiss,et al.  The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[20]  C. Weaver,et al.  CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli , 1991, Molecular and cellular biology.

[21]  C. Walsh,et al.  Purification and characterization of a soluble catalytic fragment of the human transmembrane leukocyte antigen related (LAR) protein tyrosine phosphatase from an Escherichia coli expression system. , 1991, Biochemistry.

[22]  P. Kavathas,et al.  Association of CD8 with p56lck is required for early T cell signalling events. , 1991, The EMBO journal.

[23]  K. M. Abraham,et al.  Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59 fyn ) , 1991, Cell.

[24]  A. Weiss,et al.  Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[25]  N. Shastri,et al.  Requirement for association of p56 lck with CD4 in antigen-specific signal transduction in T cells , 1991, Cell.

[26]  J. Marshall,et al.  Structural elements that regulate pp59c-fyn catalytic activity, transforming potential, and ability to associate with polyomavirus middle-T antigen , 1991, Journal of virology.

[27]  N. Abraham,et al.  Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation , 1990, Molecular and cellular biology.

[28]  M. Fournel,et al.  The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation. , 1990, Oncogene.

[29]  G. Schieven,et al.  Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[30]  A. Weiss,et al.  Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway , 1990, Nature.

[31]  H. Ostergaard,et al.  Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck , 1990, The Journal of experimental medicine.

[32]  E. Kitas,et al.  Synthesis of O-phosphotyrosine-containing peptides. 3. Synthesis of H-Pro-Tyr(P)-Val-OH via dimethyl phosphate protection and the use of improved deprotection procedures , 1990 .

[33]  R. Klausner,et al.  Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[34]  T. Mustelin,et al.  Dephosphorylation and activation of the T cell tyrosine kinase pp56lck by the leukocyte common antigen (CD45). , 1990, Oncogene.

[35]  T. Mustelin,et al.  T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation. , 1990, Science.

[36]  P. Johnson,et al.  Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[37]  Matthew L. Thomas,et al.  Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation , 1989, Cell.

[38]  T. Mustelin,et al.  Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[39]  L. Samelson,et al.  Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck , 1989, Nature.

[40]  Michael A. Bookman,et al.  The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56 lck , 1988, Cell.

[41]  C. Rudd,et al.  The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[42]  K. Amrein,et al.  Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[43]  Jonathan A. Cooper,et al.  Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck) , 1988, Molecular and cellular biology.

[44]  T. Kmiecik,et al.  Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation , 1987, Cell.

[45]  T. Roberts,et al.  Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src , 1987, Cell.

[46]  G. Galfré,et al.  Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens , 1978, European journal of immunology.

[47]  R. Kiessling,et al.  „Natural”︁ killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype , 1975, European journal of immunology.

[48]  T. Hunter,et al.  Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. , 1991, Methods in enzymology.