Endoplasmic reticulum Metallo protease 1, a triggering factor for unfolded protein response and promising target in colorectal cancer

[1]  C. Andersen,et al.  DAPK1 loss triggers tumor invasion in colorectal tumor cells , 2019, Cell Death & Disease.

[2]  G. R. van den Brink,et al.  Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling , 2019, Cell Death & Disease.

[3]  I. Majsterek,et al.  The Role of the ER-Induced UPR Pathway and the Efficacy of Its Inhibitors and Inducers in the Inhibition of Tumor Progression , 2019, Oxidative medicine and cellular longevity.

[4]  Yujie Su,et al.  miR-148b Functions as a Tumor Suppressor by Targeting Endoplasmic Reticulum Metallo Protease 1 in Human Endometrial Cancer Cells. , 2018, Oncology research.

[5]  Richard J. Jones,et al.  Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma , 2018, Proceedings of the National Academy of Sciences.

[6]  M. Heikenwalder,et al.  Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis. , 2018, Gastroenterology.

[7]  R. Amaravadi,et al.  Targeting autophagy in cancer , 2018, Cancer.

[8]  W. Chiang,et al.  ER stress and unfolded protein response in ocular health and disease , 2018, The FEBS journal.

[9]  I. Dikic,et al.  Mechanism and medical implications of mammalian autophagy , 2018, Nature reviews. Molecular cell biology.

[10]  A. Cybulsky Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases , 2017, Nature Reviews Nephrology.

[11]  A. Thorburn,et al.  Targeting autophagy in cancer , 2017, Nature Reviews Cancer.

[12]  S. Kõks,et al.  Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease , 2017, Front. Cell Dev. Biol..

[13]  G. Fimia,et al.  Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate , 2017, Front. Oncol..

[14]  P. Mokarram,et al.  Novel biotechnology approaches in colorectal cancer diagnosis and therapy , 2017, Biotechnology Letters.

[15]  F. Gage,et al.  Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges , 2017, Front. Cell. Neurosci..

[16]  Liqun Yu,et al.  Anticipatory UPR Activation: A Protective Pathway and Target in Cancer , 2016, Trends in Endocrinology & Metabolism.

[17]  I. Dixon,et al.  Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts , 2016, Oncotarget.

[18]  Liqun Yu,et al.  Interplay between steroid hormone activation of the unfolded protein response and nuclear receptor action , 2016, Steroids.

[19]  A. Santi,et al.  ERMP1, a novel potential oncogene involved in UPR and oxidative stress defense, is highly expressed in human cancer , 2016, Oncotarget.

[20]  Randal J. Kaufman,et al.  The unfolded protein response in immunity and inflammation , 2016, Nature Reviews Immunology.

[21]  W. Chan,et al.  New insights into the unfolded protein response in stem cells , 2016, Oncotarget.

[22]  Marek J. Łos,et al.  Cancer stem cells, cancer-initiating cells and methods for their detection. , 2016, Drug discovery today.

[23]  Y. Assaraf,et al.  Could drugs inhibiting the mevalonate pathway also target cancer stem cells? , 2016, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

[24]  Min Lu,et al.  Activation of IRE1α-XBP1 pathway induces cell proliferation and invasion in colorectal carcinoma. , 2016, Biochemical and biophysical research communications.

[25]  D. Schwarz,et al.  The endoplasmic reticulum: structure, function and response to cellular signaling , 2015, Cellular and Molecular Life Sciences.

[26]  W. Scheper,et al.  The unfolded protein response in neurodegenerative diseases: a neuropathological perspective , 2015, Acta Neuropathologica.

[27]  U. Ozcan,et al.  Unfolded Protein Response Signaling and Metabolic Diseases* , 2013, The Journal of Biological Chemistry.

[28]  H. Tilg,et al.  ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells , 2013, The Journal of experimental medicine.

[29]  R. Lothe,et al.  Epigenetic and genetic features of 24 colon cancer cell lines , 2013, Oncogenesis.

[30]  C. Hetz,et al.  Targeting the unfolded protein response in disease , 2013, Nature Reviews Drug Discovery.

[31]  I. Tabas,et al.  The UPR in atherosclerosis , 2013, Seminars in Immunopathology.

[32]  B. Lambrecht,et al.  The UPR and lung disease , 2013, Seminars in Immunopathology.

[33]  P. Lambin,et al.  PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS , 2013, Proceedings of the National Academy of Sciences.

[34]  D. Maddalo,et al.  The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment , 2013, Front. Pharmacol..

[35]  H. Chung,et al.  Annals of the New York Academy of Sciences Unfolded Protein Response to Autophagy as a Promising Druggable Target for Anticancer Therapy , 2022 .

[36]  M. Wicha,et al.  Identification and functional analysis of 9p24 amplified genes in human breast cancer , 2012, Oncogene.

[37]  C. Hetz The unfolded protein response: controlling cell fate decisions under ER stress and beyond , 2012, Nature Reviews Molecular Cell Biology.

[38]  P. Walter,et al.  The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation , 2011, Science.

[39]  G. Hatch,et al.  Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c. , 2010, Biochimica et biophysica acta.

[40]  K. Shin‐ya,et al.  Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation. , 2009, Cancer research.

[41]  R. Kutner,et al.  Simplified lentivirus vector production in protein-free media using polyethylenimine-mediated transfection. , 2009, Journal of virological methods.

[42]  S. Wesselborg,et al.  Role of BNIP3 in TNF-induced cell death--TNF upregulates BNIP3 expression. , 2009, Biochimica et biophysica acta.

[43]  R. Bernards Cancer: Entangled pathways , 2008, Nature.

[44]  G. Morgan,et al.  Untangling the unfolded protein response , 2008, Cell cycle.

[45]  C. Glembotski,et al.  The role of the unfolded protein response in the heart. , 2008, Journal of molecular and cellular cardiology.

[46]  P. Walter,et al.  Signal integration in the endoplasmic reticulum unfolded protein response , 2007, Nature Reviews Molecular Cell Biology.

[47]  S. Ojeda,et al.  Fxna, a novel gene differentially expressed in the rat ovary at the time of folliculogenesis, is required for normal ovarian histogenesis , 2007, Development.

[48]  D. Ron,et al.  Perk-Dependent Translational Regulation Promotes Tumor Cell Adaptation and Angiogenesis in Response to Hypoxic Stress , 2006, Molecular and Cellular Biology.

[49]  M. Lai,et al.  Overexpression of glucose-regulated protein 78 in colon cancer. , 2006, Clinica chimica acta; international journal of clinical chemistry.

[50]  K. Mori,et al.  Dysfunction of the Unfolded Protein Response during Global Brain Ischemia and Reperfusion , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[51]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[52]  A. Chaudhary,et al.  Endoplasmic reticulum-mediated unfolded protein response and mitochondrial apoptosis in cancer. , 2017, Biochimica et biophysica acta. Reviews on cancer.

[53]  Kenji Ogawa,et al.  Overexpression of human X-box binding protein 1 (XBP-1) in colorectal adenomas and adenocarcinomas. , 2007, Anticancer research.