Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2
暂无分享,去创建一个
Rong Li | Ningning Li | L. Tao | Guopeng Wang | Ning Gao | R. Ren | Qihang Zhong | Honglei Chu | Jing Hang | Xiaoguang Lei | Youli Zhou | Fusheng Guo | J. Hang | Cheng Zhang | J. Qiao | Xinlu Meng | Yuan Wei
[1] J. Jumper,et al. Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition , 2022, Nature Communications.
[2] N. Sang,et al. Stanniocalcin 2 (STC2): a universal tumour biomarker and a potential therapeutical target , 2022, Journal of experimental & clinical cancer research : CR.
[3] C. Conover,et al. Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy. , 2022, Metabolism: clinical and experimental.
[4] M. DePristo,et al. RNA profiles reveal signatures of future health and disease in pregnancy , 2022, Nature.
[5] J. Qin,et al. Establishment of Trophoblast‐Like Tissue Model from Human Pluripotent Stem Cells in Three‐Dimensional Culture System , 2021, Advanced science.
[6] D. Hassabis,et al. Protein complex prediction with AlphaFold-Multimer , 2021, bioRxiv.
[7] K. Yanagihara,et al. Cancer‐associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T‐cell suppression , 2021, Molecular oncology.
[8] Oriol Vinyals,et al. Highly accurate protein structure prediction with AlphaFold , 2021, Nature.
[9] A. Urban,et al. PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percreta† , 2021, Biology of Reproduction.
[10] R. Baron,et al. Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells , 2021, Aging cell.
[11] Tiffany DeSouza,et al. PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans , 2020, Science Translational Medicine.
[12] G. Zuccotti,et al. Placental proteome abnormalities in women with gestational diabetes and large-for-gestational-age newborns , 2020, BMJ Open Diabetes Research & Care.
[13] A. Urban,et al. PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percreta† , 2020, Biology of Reproduction.
[14] A. Joshi. New Insights Into Physiological and Pathophysiological Functions of Stanniocalcin 2 , 2020, Frontiers in Endocrinology.
[15] J. Potempa,et al. Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases , 2020, IUCrJ.
[16] S. Walker,et al. The untapped potential of placenta-enriched molecules for diagnostic and therapeutic development. , 2019, Placenta.
[17] J. Frystyk,et al. The IGF system in patients with inflammatory bowel disease treated with prednisolone or infliximab: potential role of the stanniocalcin-2 / PAPP-A / IGFBP-4 axis , 2019, BMC Gastroenterology.
[18] I. Sandovici,et al. The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth , 2019, bioRxiv.
[19] E. Hohenester. Laminin G-like domains: dystroglycan-specific lectins. , 2019, Current opinion in structural biology.
[20] Erik Lindahl,et al. New tools for automated high-resolution cryo-EM structure determination in RELION-3 , 2018, eLife.
[21] R. Hjortebjerg. IGFBP-4 and PAPP-A in normal physiology and disease. , 2018, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[22] Cheng Zhu,et al. Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta , 2018, Cell Research.
[23] C. Conover,et al. PAPP-A and cancer. , 2018, Journal of molecular endocrinology.
[24] G. Kristiansen,et al. Extravillous trophoblast invasion of venous as well as lymphatic vessels is altered in idiopathic, recurrent, spontaneous abortions , 2017, Human reproduction.
[25] D. Agard,et al. MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy , 2017, Nature Methods.
[26] C. Conover,et al. PAPP‐A: a promising therapeutic target for healthy longevity , 2016, Aging cell.
[27] Marcelo P. Segura-Lepe,et al. Rare and low-frequency coding variants alter human adult height , 2016, Nature.
[28] C. Oxvig,et al. PAPP-A and the IGF system. , 2016, Annales d'endocrinologie.
[29] D. Tincello,et al. Role of serum biomarkers in the prediction of outcome in women with threatened miscarriage: a systematic review and diagnostic accuracy meta-analysis. , 2015, Human reproduction update.
[30] C. Oxvig,et al. Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A* , 2015, The Journal of Biological Chemistry.
[31] Kai Zhang,et al. Gctf: Real-time CTF determination and correction , 2015, bioRxiv.
[32] E. Füchtbauer,et al. Stanniocalcin-2 Inhibits Mammalian Growth by Proteolytic Inhibition of the Insulin-like Growth Factor Axis* , 2014, The Journal of Biological Chemistry.
[33] R. Baxter,et al. IGF binding proteins in cancer: mechanistic and clinical insights , 2014, Nature Reviews Cancer.
[34] J. Kopchick,et al. The GH/IGF-1 axis in ageing and longevity , 2013, Nature Reviews Endocrinology.
[35] M. Pollak. The insulin and insulin-like growth factor receptor family in neoplasia: an update , 2012, Nature Reviews Cancer.
[36] S. Glerup,et al. Placental Regulation of Peptide Hormone and Growth Factor Activity by proMBP1 , 2011, Biology of reproduction.
[37] N. Uldbjerg,et al. Biology of pregnancy‐associated plasma protein‐A in relation to prenatal diagnostics: an overview , 2010, Acta obstetricia et gynecologica Scandinavica.
[38] Ayellet V. Segrè,et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height , 2010, Nature.
[39] P. Emsley,et al. Features and development of Coot , 2010, Acta crystallographica. Section D, Biological crystallography.
[40] Randy J. Read,et al. Acta Crystallographica Section D Biological , 2003 .
[41] A. Chao,et al. Clinical outcome and placental territory ratio of monochorionic twin pregnancies and selective intrauterine growth restriction with different types of umbilical artery Doppler , 2009, Prenatal Diagnosis.
[42] M. V. van Gemert,et al. Placental characteristics of monochorionic diamniotic twin pregnancies in relation to perinatal outcome. , 2008, Placenta.
[43] M. Overgaard,et al. Inhibition of the Proteolytic Activity of Pregnancy-associated Plasma Protein-A by Targeting Substrate Exosite Binding* , 2008, Journal of Biological Chemistry.
[44] J. Deprest,et al. A classification system for selective intrauterine growth restriction in monochorionic pregnancies according to umbilical artery Doppler flow in the smaller twin , 2007, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.
[45] M. Christiansen,et al. Quantification of proteolytically active pregnancy-associated plasma protein-A with an assay based on quenched fluorescence. , 2007, Clinical chemistry.
[46] C. Oxvig,et al. A Substrate Specificity-determining Unit of Three Lin12-Notch Repeat Modules Is Formed in Trans within the Pappalysin-1 Dimer and Requires a Sequence Stretch C-terminal to the Third Module* , 2007, Journal of Biological Chemistry.
[47] M. E. Ferretti,et al. Control of human trophoblast function , 2007, Reproductive biology and endocrinology : RB&E.
[48] C. Conover,et al. Pregnancy-associated plasma protein-A (PAPP-A): a local regulator of IGF bioavailability through cleavage of IGFBPs. , 2007, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[49] S. Thiel,et al. Cell Surface Detachment of Pregnancy-associated Plasma Protein-A Requires the Formation of Intermolecular Proteinase-Inhibitor Disulfide Bonds and Glycosaminoglycan Covalently Bound to the Inhibitor* , 2007, Journal of Biological Chemistry.
[50] U. Baumann,et al. Substrate specificity of a metalloprotease of the pappalysin family revealed by an inhibitor and a product complex. , 2007, Archives of biochemistry and biophysics.
[51] P. Mahadevan,et al. An overview , 2007, Journal of Biosciences.
[52] U. Baumann,et al. Molecular Analysis of Ulilysin, the Structural Prototype of a New Family of Metzincin Metalloproteases* , 2006, Journal of Biological Chemistry.
[53] David N Mastronarde,et al. Automated electron microscope tomography using robust prediction of specimen movements. , 2005, Journal of structural biology.
[54] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[55] L. Giudice,et al. The Lin12-Notch Repeats of Pregnancy-associated Plasma Protein-A Bind Calcium and Determine Its Proteolytic Specificity* , 2004, Journal of Biological Chemistry.
[56] M. Overgaard,et al. Proteolytic degradation of IGF-binding protein (IGFBP)-2 in equine ovarian follicles: involvement of pregnancy-associated plasma protein-A (PAPP-A) and association with dominant but not subordinated follicles. , 2004, The Journal of endocrinology.
[57] L. Giudice,et al. Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module. , 2004, European journal of biochemistry.
[58] B. Huppertz,et al. Endovascular Trophoblast Invasion: Implications for the Pathogenesis of Intrauterine Growth Retardation and Preeclampsia , 2003, Biology of reproduction.
[59] J. E. Fortune,et al. Selection of the dominant follicle and insulin-like growth factor (IGF)-binding proteins: evidence that pregnancy-associated plasma protein A contributes to proteolysis of IGF-binding protein 5 in bovine follicular fluid. , 2003, Endocrinology.
[60] M. Overgaard,et al. Complex of Pregnancy-associated Plasma Protein-A and the Proform of Eosinophil Major Basic Protein , 2003, The Journal of Biological Chemistry.
[61] L. Giudice,et al. Cell Surface Targeting of Pregnancy-associated Plasma Protein A Proteolytic Activity , 2002, The Journal of Biological Chemistry.
[62] Kathrin H Hopmann,et al. Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis. , 2002, The Biochemical journal.
[63] K. Godfrey. The role of the placenta in fetal programming-a review. , 2002, Placenta.
[64] L. Giudice,et al. Adhesion of pregnancy-associated plasma protein-A, PAGE 1 Cell surface targeting of pregnancy-associated plasma protein-A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats* , 2002 .
[65] M. Overgaard,et al. Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin. , 2001, The Biochemical journal.
[66] G. J. Swaminathan,et al. Crystal Structure of the Eosinophil Major Basic Protein at 1.8 Å , 2001, Journal of Biological Chemistry.
[67] C. Conover,et al. Expression of Recombinant Human Pregnancy-associated Plasma Protein-A and Identification of the Proform of Eosinophil Major Basic Protein as Its Physiological Inhibitor* , 2000, The Journal of Biological Chemistry.
[68] S. Mohan,et al. Evidence that the interaction between insulin-like growth factor (IGF)-II and IGF binding protein (IGFBP)-4 is essential for the action of the IGF-II-dependent IGFBP-4 protease. , 2000, Archives of biochemistry and biophysics.
[69] N. Wald,et al. Integrated screening for Down's syndrome based on tests performed during the first and second trimesters. , 1999, The New England journal of medicine.
[70] N. Moody. Untapped Potential , 1997 .
[71] C. Oxvig,et al. Isolation and characterization of circulating complex between human pregnancy-associated plasma protein-A and proform of eosinophil major basic protein. , 1994, Biochimica et biophysica acta.
[72] C. Oxvig,et al. Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein. , 1993, The Journal of biological chemistry.
[73] K. Johnson. An Update. , 1984, Journal of food protection.
[74] J. Grudzinskas,et al. Pregnancy-associated plasma protein A: circulating levels during normal pregnancy. , 1981, American journal of obstetrics and gynecology.
[75] W. Spellacy,et al. Characterization of four human pregnancy-associated plasma proteins. , 1974, American journal of obstetrics and gynecology.