Zinc protects endothelial cells from hydrogen peroxide via Nrf2-dependent stimulation of glutathione biosynthesis.
暂无分享,去创建一个
[1] W. Maret,et al. The zinc/thiolate redox biochemistry of metallothionein and the control of zinc ion fluctuations in cell signaling. , 2007, Archives of biochemistry and biophysics.
[2] J. Laity,et al. Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1). , 2007, Archives of biochemistry and biophysics.
[3] A. Prasad. Zinc: mechanisms of host defense. , 2007, The Journal of nutrition.
[4] Shyam Biswal,et al. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. , 2007, Annual review of pharmacology and toxicology.
[5] S. Black,et al. Endothelial response to stress from exogenous Zn2+ resembles that of NO-mediated nitrosative stress, and is protected by MT-1 overexpression. , 2006, American journal of physiology. Cell physiology.
[6] Z. Suntres,et al. Antioxidant effect of zinc and zinc-metallothionein in the acute cytotoxicity of hydrogen peroxide in Ehrlich ascites tumour cells. , 2006, Chemico-biological interactions.
[7] N. Kaplowitz,et al. Mechanisms of liver injury. III. Role of glutathione redox status in liver injury. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[8] Jiyang Cai,et al. Increased glutathione synthesis through an ARE-Nrf2-dependent pathway by zinc in the RPE: implication for protection against oxidative stress. , 2006, Investigative ophthalmology & visual science.
[9] B. Rovin,et al. Activation of Nrf2/ARE pathway protects endothelial cells from oxidant injury and inhibits inflammatory gene expression. , 2006, American journal of physiology. Heart and circulatory physiology.
[10] C. Bediz,et al. Zinc supplementation ameliorates electromagnetic field-induced lipid peroxidation in the rat brain. , 2006, The Tohoku journal of experimental medicine.
[11] Dean P. Jones,et al. The Role of the Multidrug Resistance Protein-1 in Modulation of Endothelial Cell Oxidative Stress , 2005, Circulation research.
[12] Shelly C. Lu,et al. Nrf1 and Nrf2 Regulate Rat Glutamate-Cysteine Ligase Catalytic Subunit Transcription Indirectly via NF-κB and AP-1 , 2005, Molecular and Cellular Biology.
[13] C. Hogstrand,et al. ZINC-mediated gene expression offers protection against H2O2-induced cytotoxicity. , 2005, Toxicology and applied pharmacology.
[14] O. Kucuk,et al. Supplementation of zinc from organic or inorganic source improves performance and antioxidant status of heat-distressed quail. , 2005, Poultry science.
[15] A. Dinkova-Kostova,et al. Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein. , 2005, Biochemistry.
[16] G. Nickenig,et al. Modulation of oxidant and antioxidant enzyme expression and function in vascular cells. , 2004, Hypertension.
[17] H. Nakagawa,et al. Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate. , 2004, Carcinogenesis.
[18] R. Palmiter. Protection against zinc toxicity by metallothionein and zinc transporter 1. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[19] W. Maret. Zinc and sulfur: a critical biological partnership. , 2004, Biochemistry.
[20] Guoyao Wu,et al. Glutathione metabolism and its implications for health. , 2004, The Journal of nutrition.
[21] P. Oteiza,et al. Influence of zinc deficiency on cell-membrane fluidity in Jurkat, 3T3 and IMR-32 cells. , 2004, The Biochemical journal.
[22] J. Beattie,et al. Is zinc deficiency a risk factor for atherosclerosis? , 2004, The British journal of nutrition.
[23] B. Ames,et al. Zinc deficiency induces oxidative DNA damage and increases p53 expression in human lung fibroblasts. , 2003, The Journal of nutrition.
[24] M. Popp,et al. A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[25] Shin Aoki,et al. A macrocyclic zinc(II) fluorophore as a detector of apoptosis , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[26] J. Alam,et al. Degradation of Transcription Factor Nrf2 via the Ubiquitin-Proteasome Pathway and Stabilization by Cadmium* , 2003, The Journal of Biological Chemistry.
[27] B. Ames,et al. Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFκB, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[28] R. Mulcahy,et al. Identification of a Variant Antioxidant Response Element in the Promoter of the Human Glutamate-Cysteine Ligase Modifier Subunit Gene , 2002, The Journal of Biological Chemistry.
[29] Zuzana Dobbie,et al. Processing of gene expression data generated by quantitative real-time RT-PCR. , 2002, BioTechniques.
[30] C. S. St. Croix,et al. Role of zinc in pulmonary endothelial cell response to oxidative stress. , 2001, American journal of physiology. Lung cellular and molecular physiology.
[31] C. Suschek,et al. Even after UVA-exposure will nitric oxide protect cells from reactive oxygen intermediate-mediated apoptosis and necrosis , 2001, Cell Death and Differentiation.
[32] Y. Kan,et al. An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[33] J. Chan,et al. Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein. , 2000, Biochimica et biophysica acta.
[34] G. Andrews,et al. The Transcription Factor MTF-1 Mediates Metal Regulation of the Mouse ZnT1 Gene* , 2000, The Journal of Biological Chemistry.
[35] A. Choi,et al. Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. , 2000, The Journal of biological chemistry.
[36] J. Fanzo,et al. Expression of the p53 tumor suppressor gene is up-regulated by depletion of intracellular zinc in HepG2 cells. , 2000, The Journal of nutrition.
[37] S. Powell. The antioxidant properties of zinc. , 2000, The Journal of nutrition.
[38] Wild Ac,et al. Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. , 1999 .
[39] O. Griffith,et al. Biologic and pharmacologic regulation of mammalian glutathione synthesis. , 1999, Free radical biology & medicine.
[40] Y. Kan,et al. Nrf2 is essential for protection against acute pulmonary injury in mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[41] A. Choi,et al. Nrf2, a Cap’n’Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene* , 1999, The Journal of Biological Chemistry.
[42] K. Higashi,et al. Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of the Bcl-2/Bax ratio. , 1998, Biochemical and biophysical research communications.
[43] A. Aguzzi,et al. Embryonic Lethality and Liver Degeneration in Mice Lacking the Metal-responsive Transcriptional Activator Mtf-1 Embryonic Lethality and Liver Degeneration in Mice Lacking the Metal-responsive Transcriptional Activator Mtf-1 Embryonic Lethality and Liver Degeneration in Mice Lacking the Metal-respons , 2022 .
[44] R. Mulcahy,et al. Identification of a putative antioxidant response element in the 5'-flanking region of the human gamma-glutamylcysteine synthetase heavy subunit gene. , 1995, Biochemical and biophysical research communications.
[45] C. Fraga,et al. Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. , 1995, The Journal of nutrition.
[46] R. Palmiter,et al. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. , 1995, The EMBO journal.
[47] Y. Kan,et al. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[48] C. Suschek,et al. Primary cultures of rat islet capillary endothelial cells. Constitutive and cytokine-inducible macrophagelike nitric oxide synthases are expressed and activities regulated by glucose concentration. , 1994, The American journal of pathology.
[49] W. Schaffner,et al. The transcription factor MTF‐1 is essential for basal and heavy metal‐induced metallothionein gene expression. , 1994, The EMBO journal.
[50] P. Talalay,et al. Chemical and molecular regulation of enzymes that detoxify carcinogens. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[51] H. Carlsen,et al. Polyphenols and glutathione synthesis regulation. , 2005, The American journal of clinical nutrition.
[52] B. Vallee,et al. The biochemical basis of zinc physiology. , 1993, Physiological reviews.