Versatile and open software for comparing large genomes

The newest version of MUMmer easily handles comparisons of large eukaryotic genomes at varying evolutionary distances, as demonstrated by applications to multiple genomes. Two new graphical viewing tools provide alternative ways to analyze genome alignments. The new system is the first version of MUMmer to be released as open-source software. This allows other developers to contribute to the code base and freely redistribute the code. The MUMmer sources are available at http://www.tigr.org/software/mummer.

[1]  Peter Weiner,et al.  Linear Pattern Matching Algorithms , 1973, SWAT.

[2]  Edward M. McCreight,et al.  A Space-Economical Suffix Tree Construction Algorithm , 1976, JACM.

[3]  M S Waterman,et al.  Identification of common molecular subsequences. , 1981, Journal of molecular biology.

[4]  J. P. Dumas,et al.  Efficient algorithms for folding and comparing nucleic acid sequences , 1982, Nucleic Acids Res..

[5]  D. Lipman,et al.  Improved tools for biological sequence comparison. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[6]  E. Myers,et al.  Basic local alignment search tool. , 1990, Journal of molecular biology.

[7]  Owen White,et al.  TIGR Assembler: A New Tool for Assembling Large Shotgun Sequencing Projects , 1995 .

[8]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[9]  Dan Gusfield,et al.  Algorithms on Strings, Trees, and Sequences - Computer Science and Computational Biology , 1997 .

[10]  Dan Gusfield Algorithms on Strings, Trees, and Sequences - Computer Science and Computational Biology , 1997 .

[11]  Dan Gusfield,et al.  Algorithms on Strings, Trees, and Sequences - Computer Science and Computational Biology , 1997 .

[12]  Mark Borodovsky,et al.  The complete genome sequence of the gastric pathogen Helicobacter pylori , 1997, Nature.

[13]  P. Green,et al.  Consed: a graphical tool for sequence finishing. , 1998, Genome research.

[14]  Benjamin L. King,et al.  Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori , 1999, Nature.

[15]  Stefan Kurtz,et al.  Reducing the space requirement of suffix trees , 1999, Softw. Pract. Exp..

[16]  S. Salzberg,et al.  Alignment of whole genomes. , 1999, Nucleic acids research.

[17]  X. Huang,et al.  CAP3: A DNA sequence assembly program. , 1999, Genome research.

[18]  W R Pearson,et al.  Flexible sequence similarity searching with the FASTA3 program package. , 2000, Methods in molecular biology.

[19]  Eugene W. Myers,et al.  A whole-genome assembly of Drosophila. , 2000, Science.

[20]  J. Stoye,et al.  REPuter: the manifold applications of repeat analysis on a genomic scale. , 2001, Nucleic acids research.

[21]  J. Mullikin,et al.  SSAHA: a fast search method for large DNA databases. , 2001, Genome research.

[22]  Enno Ohlebusch,et al.  Efficient multiple genome alignment , 2002, ISMB.

[23]  Jonathan E. Allen,et al.  Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii , 2002, Nature.

[24]  Mouse Genome Sequencing Consortium Initial sequencing and comparative analysis of the mouse genome , 2002, Nature.

[25]  S. Salzberg,et al.  Whole-Genome Comparison of Mycobacterium tuberculosis Clinical and Laboratory Strains , 2002, Journal of bacteriology.

[26]  Mihai Pop,et al.  Comparative Genome Sequencing for Discovery of Novel Polymorphisms in Bacillus anthracis , 2002, Science.

[27]  B. Berger,et al.  ARACHNE: a whole-genome shotgun assembler. , 2002, Genome research.

[28]  Colin N. Dewey,et al.  Initial sequencing and comparative analysis of the mouse genome. , 2002 .

[29]  Peer Bork,et al.  Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster , 2002, Science.

[30]  S. Salzberg,et al.  Fast algorithms for large-scale genome alignment and comparison. , 2002, Nucleic acids research.

[31]  Nicholas L. Bray,et al.  AVID: A global alignment program. , 2003, Genome research.

[32]  D. Haussler,et al.  Human-mouse alignments with BLASTZ. , 2003, Genome research.

[33]  J. Mullikin,et al.  The phusion assembler. , 2003, Genome research.

[34]  Chuong B. Do,et al.  Access the most recent version at doi: 10.1101/gr.926603 References , 2003 .

[35]  S. Salzberg,et al.  The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria , 2003, Nature.

[36]  Enno Ohlebusch,et al.  An Applications-focused Review of Comparative Genomics Tools: Capabilities, Limitations and Future Challenges , 2003, Briefings Bioinform..