Day‐restricted feeding during pregnancy and lactation programs glucose intolerance and impaired insulin secretion in male rat offspring

The maternal environment during pregnancy and lactation plays a determining role in programming energy metabolism in offspring. Among a myriad of maternal factors, disruptions in the light/dark cycle during pregnancy can program glucose intolerance in offspring. Out‐of‐phase feeding has recently been reported to influence metabolism in adult humans and rodents; however, it is not known whether this environmental factor impacts offspring metabolism when applied during pregnancy and lactation. This study aims to determine whether maternal day‐restricted feeding (DF) influences energy metabolism in offspring.

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