Modelling of a case-based retrieval system for oncology

When a new patient does not comply with the guidelines, experts base their therapeutic decisions on similar patients' cases they have treated in the past. The case-based reasoning decision-support system we propose will automatically compare the patient's case to the structured guideline, then to other cases, and retrieve similar cases. The general structure of the system is presented here, the domain of application being oncology. As the patients' records are not stored in the current database in a format directly exploitable, an object-oriented model is proposed, that includes prognosis factors currently tested in clinical trials, well-established ones, and a description of the illness' episodes. Such system does not exist in the literature. It can be viewed as a data warehouse. Future work consists in defining the similarity measures, and connecting the system to the current database.

[1]  Mathieu d'Aquin,et al.  The Kasimir Project: Knowledge Management in Cancerology , 2002 .

[2]  Rainer Schmidt,et al.  Case-based reasoning for antibiotics therapy advice: an investigation of retrieval algorithms and prototypes , 2001, Artif. Intell. Medicine.

[3]  Omolola Ogunyemi,et al.  GLIF3: the evolution of a guideline representation format , 2000, AMIA.

[4]  Patrice Degoulet,et al.  Unified modeling language and design of a case-based retrieval system in medical imaging , 1998, AMIA.

[5]  Agnar Aamodt,et al.  Case-Based Reasoning: Foundational Issues, Methodological Variations, and System Approaches , 1994, AI Commun..

[6]  Samson W. Tu,et al.  Modeling Data and Knowledge in the EON Guideline Architecture , 2001, MedInfo.

[7]  Patrice Degoulet,et al.  Case Based Diagnosis in Histopathology of Breast Tumours , 1998, MedInfo.

[8]  Luigi Portinale,et al.  A multi-modal reasoning methodology for managing IDDM patients , 2000, Int. J. Medical Informatics.

[9]  L D Xu,et al.  An integrated rule- and case-based approach to AIDS initial assessment. , 1996, International journal of bio-medical computing.

[10]  Donald L Weaver,et al.  Revision of the American Joint Committee on Cancer staging system for breast cancer. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[11]  Samson W. Tu,et al.  A virtual medical record for guideline-based decision support , 2001, AMIA.

[12]  Jeffrey M. Bradshaw,et al.  CARE-PARTNER: a computerized knowledge-support system for stem-cell post-transplant long-term follow-up on the World-Wide-Web , 1998, AMIA.

[13]  Jacques Bouaud,et al.  ONCODOC: a successful experiment of computer-supported guideline development and implementation in the treatment of breast cancer , 2001, Artif. Intell. Medicine.