Analysis of the GLARE and GPROVE Approaches to Clinical Guidelines

Clinical guidelines (GLs) play an important role in medical practice, and computerized support to GLs is now one of the most central areas of research in Artificial Intelligence in medicine. In recent years, many groups have developed different computer-assisted management systems of GL. Each approach has its own peculiarities and thus a comparison is necessary. Many possible aspects can be analyzed, but a first analysis has probably to consider the GL models, i.e. the representation formalisms provided. To this end, Peleg and al. [4] have analyzed and compared six different frameworks. In this paper, we analyse also GLARE and GPROVE on the basis of the same methodology. Moreover, we extend such analysis by considering the tools and the facilities that GLARE and GPROVE provide to support the use of GLs. The final goal of our analysis is to exploit the differences between these two systems and if they can be fruitfully integrated.

[1]  Paolo Terenziani,et al.  Suppor ting Physicians in Taking Decisions in Clinical Guidelines : the GLARE “ What if ” , 2022 .

[2]  Paola Mello,et al.  A Hybrid Approach to Clinical Guideline and to Basic Medical Knowledge Conformance , 2009, AIME.

[3]  John Fox,et al.  Disseminating medical knowledge: the PROforma approach , 1998, Artif. Intell. Medicine.

[4]  Alessio Bottrighi,et al.  Supporting physicians in taking decisions in clinical guidelines: the GLARE "what if" facility , 2002, AMIA.

[5]  P. Ram,et al.  SAGEDesktop: An Environment for Testing Clinical Practice Guidelines , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[6]  Orna Grumberg,et al.  A game-based framework for CTL counterexamples and 3-valued abstraction-refinement , 2007, TOCL.

[7]  Robert A. Greenes,et al.  Research Paper: The GuideLine Interchange Format: A Model for Representing Guidelines , 1998, J. Am. Medical Informatics Assoc..

[8]  Evelina Lamma,et al.  Compliance Checking of Cancer-Screening CareFlows: an Approach based on Computational Logic , 2008, Computer-based Medical Guidelines and Protocols.

[9]  Alessio Bottrighi,et al.  Towards a comprehensive treatment of repetitions, periodicity and temporal constraints in clinical guidelines , 2006, Artif. Intell. Medicine.

[10]  Yuval Shahar,et al.  Synthesis of Research: EON: A Component-Based Approach to Automation of Protocol-Directed Therapy , 1996, J. Am. Medical Informatics Assoc..

[11]  R. Irwin,et al.  The New “Face” of CHEST Heralds a New Era , 2006 .

[12]  Gerard J. Holzmann,et al.  The SPIN Model Checker - primer and reference manual , 2003 .

[13]  Omolola Ogunyemi,et al.  GLIF3: the evolution of a guideline representation format , 2000, AMIA.

[14]  Paola Mello,et al.  A Framework for Defining and Verifying Clinical Guidelines: A Case Study on Cancer Screening , 2006, ISMIS.

[15]  Nick Booth,et al.  Using scenarios in chronic disease management guidelines for primary care , 2000, AMIA.

[16]  Evelina Lamma,et al.  Verifiable agent interaction in abductive logic programming: The SCIFF framework , 2008, TOCL.

[17]  L. Boulet,et al.  Managing cough as a defense mechanism and as a symptom. A consensus panel report of the American College of Chest Physicians. , 1998, Chest.

[18]  Michael J. Maher,et al.  Constraint Logic Programming: A Survey , 1994, J. Log. Program..

[19]  Alessio Bottrighi,et al.  A Context-Adaptable Approach to Clinical Guidelines , 2004, MedInfo.

[20]  L. Boulet,et al.  Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. , 2006, Chest.

[21]  Arie Hasman,et al.  Design and implementation of a framework to support the development of clinical guidelines , 2001, Int. J. Medical Informatics.

[22]  T Wetter,et al.  HELEN, a Modular Framework for Representing and Implementing Clinical Practice Guidelines , 2004, Methods of Information in Medicine.

[23]  Evelina Lamma,et al.  The SCIFF Abductive Proof-Procedure , 2005, AI*IA.

[24]  John Fox,et al.  Comparing computer-interpretable guideline models: a case-study approach. , 2003, Journal of the American Medical Informatics Association : JAMIA.

[25]  Evelina Lamma,et al.  Computer-based Medical Guidelines and Protocols: A Primer and Current Trends , 2008, Computer-based Medical Guidelines and Protocols.

[26]  Paolo Terenziani,et al.  Exploiting decision theory concepts within clinical guideline systems: Toward a general approach: Research Articles , 2006 .

[27]  Antonio Moreno,et al.  Distributed Guideline-Based Health Care System , 2004 .

[28]  Alessio Bottrighi,et al.  Applying Artificial Intelligence to Clinical Guidelines: The GLARE Approach , 2003, AI*IA.

[29]  Yuval Shahar,et al.  ASBRU: A TASK-SPECIFIC, INTENTION-BASED, AND TIME-ORIENTED LANGUAGE FOR REPRESENTING SKELETAL PLANS , 1999 .

[30]  Gerard J. Holzmann,et al.  The SPIN Model Checker , 2003 .

[31]  Kudakwashe Dube,et al.  A Generic Approach to Supporting the Management of Computerised Clinical Guidelines and Protocols , 2004 .

[32]  Peter J. F. Lucas Computer-based Medical Guidelines and Protocols: A Primer and Current Trends , 2008 .

[33]  Silvana Quaglini,et al.  Guideline-based careflow systems , 2000, Artif. Intell. Medicine.

[34]  J. P. Christensen,et al.  Health telematics for clinical guidelines and protocols , 1995 .