Involvement of NLK and Sox11 in neural induction in Xenopus development

Background : The Wnt signal transduction pathway regulates various aspects of embryonal development and has been implicated in promoting cancer. Signalling by Wnts leads to the stabilization of cytosolic β‐catenin, which then associates with TCF transcription factors to regulate expression of Wnt‐target genes. The Wnt pathway is further subject to cross‐regulation at various levels by other components.

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