Cytomegalovirus (CMV) Encephalitis in HIV Patients

It is hypothesized that impaired CD4 cell functioning is attributable to viral replication. Most cases of CMV encephalitis occur when CD4 counts fall below 50, however patients may be predisposed to CMV infection prior to depletion of CD4 [1]. Previous opportunistic infections (OIs), a high level of CMV viremia, and high plasma HIV RNA levels (>100,000 copies/mL) are other reported risk factors [2].

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