Estimating Future Health Technology Diffusion Using Expert Beliefs Calibrated to an Established Diffusion Model.

OBJECTIVES Estimates of future health technology diffusion, or future uptake over time, are a requirement for different analyses performed within health technology assessments. Methods for obtaining such estimates include constant uptake estimates based on expert opinion or analogous technologies and on extrapolation from initial data points using parametric curves-but remain divorced from established diffusion theory and modeling. We propose an approach to obtaining diffusion estimates using experts' beliefs calibrated to an established diffusion model to address this methodologic gap. METHODS We performed an elicitation of experts' beliefs on future diffusion of a new preterm birth screening illustrative case study technology. The elicited quantities were chosen such that they could be calibrated to yield the parameters of the Bass model of new product growth, which was chosen based on a review of the diffusion literature. RESULTS With the elicitation of only three quantities per diffusion curve, our approach enabled us to quantify uncertainty about diffusion of the new technology in different scenarios. Pooled results showed that the attainable number of adoptions was predicted to be relatively low compared with what was thought possible. Further research evidence improved the attainable number of adoptions only slightly but resulted in greater speed of diffusion. CONCLUSIONS The proposed approach of eliciting experts' beliefs about diffusion and informing the Bass model has the potential to fill the methodologic gap evident in value of implementation and research, as well as budget impact and some cost-effectiveness analyses.

[1]  S. Dixon,et al.  Title: Getting cost-effective technologies into practice: the value of implementation. Report on framework for valuing implementation initiatives. , 2014 .

[2]  Frank M. Bass,et al.  DIRECTV: Forecasting Diffusion of a New Technology Prior to Product Launch , 2001 .

[3]  Andrew R Willan,et al.  Optimal clinical trial design using value of information methods with imperfect implementation. , 2009, Health economics.

[4]  A. O'Hagan,et al.  Statistical Methods for Eliciting Probability Distributions , 2005 .

[5]  M Sculpher,et al.  Evaluating the cost-effectiveness of interventions designed to increase the utilization of evidence-based guidelines. , 2000, Family practice.

[6]  Karl Claxton,et al.  Characterizing structural uncertainty in decision analytic models: a review and application of methods. , 2009, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[7]  Claire Packer,et al.  International diffusion of new health technologies: A ten-country analysis of six health technologies , 2006, International Journal of Technology Assessment in Health Care.

[8]  Daisuke Satoh,et al.  A DISCRETE BASS MODEL AND ITS PARAMETER ESTIMATION , 2001 .

[9]  N Freemantle,et al.  When is it cost-effective to change the behavior of health professionals? , 2001, JAMA.

[10]  Pilsung Kang,et al.  Pre-launch new product demand forecasting using the Bass model: : A statistical and machine learning-based approach , 2014 .

[11]  Valesca P Retèl,et al.  Scenario drafting to anticipate future developments in technology assessment , 2012, BMC Research Notes.

[12]  S. Dixon,et al.  How to Invest in Getting Cost-effective Technologies into Practice? A Framework for Value of Implementation Analysis Applied to Novel Oral Anticoagulants , 2017, Medical decision making : an international journal of the Society for Medical Decision Making.

[13]  Donald R. Lehmann,et al.  A Meta-Analysis of Applications of Diffusion Models , 1990 .

[14]  Taegu Kim,et al.  Forecasting diffusion of innovative technology at pre-launch: A survey-based method , 2013, Ind. Manag. Data Syst..

[15]  E. Rogers,et al.  Diffusion of innovations , 1964, Encyclopedia of Sport Management.

[16]  J. Peters,et al.  Methods to Elicit Probability Distributions from Experts: A Systematic Review of Reported Practice in Health Technology Assessment , 2013, PharmacoEconomics.

[17]  S. Dixon,et al.  When Future Change Matters: Modeling Future Price and Diffusion in Health Technology Assessments of Medical Devices. , 2016, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[18]  Sindhu R Johnson,et al.  Methods to elicit beliefs for Bayesian priors: a systematic review. , 2010, Journal of clinical epidemiology.

[19]  S. Walker,et al.  Value for money and the Quality and Outcomes Framework in primary care in the UK NHS. , 2010, The British journal of general practice : the journal of the Royal College of General Practitioners.

[20]  S. Dixon,et al.  Estimating the Cost-Effectiveness of Implementation: Is Sufficient Evidence Available? , 2016, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[21]  Zhengrui Jiang,et al.  Virtual Bass Model and the Left-Hand Data-Truncation Bias in Diffusion of Innovation Studies , 2006 .

[22]  K. Payne,et al.  Reporting Guidelines for the Use of Expert Judgement in Model-Based Economic Evaluations , 2016, PharmacoEconomics.

[23]  Martin Hoyle,et al.  Whose Costs and Benefits? Why Economic Evaluations Should Simulate Both Prevalent and All Future Incident Patient Cohorts , 2010, Medical decision making : an international journal of the Society for Medical Decision Making.

[24]  Nicky Cullum,et al.  Methods to elicit experts’ beliefs over uncertain quantities: application to a cost effectiveness transition model of negative pressure wound therapy for severe pressure ulceration , 2011, Statistics in medicine.

[25]  D. Winterfeldt,et al.  Nuclear waste and future societies: A look into the deep future , 1997 .

[26]  Mark Nuijten,et al.  Principles of good practice for budget impact analysis: report of the ISPOR Task Force on good research practices--budget impact analysis. , 2007, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[27]  M. Dolores Gallego,et al.  Exploring the application of the Delphi method as a forecasting tool in Information Systems and Technologies research , 2014, Technol. Anal. Strateg. Manag..

[28]  Simon Dixon,et al.  Assessing the Expected Value of Research Studies in Reducing Uncertainty and Improving Implementation Dynamics , 2016, Medical decision making : an international journal of the Society for Medical Decision Making.

[29]  N. Meade,et al.  Modelling and forecasting the diffusion of innovation – A 25-year review , 2006 .

[30]  Jeremy E. Oakley,et al.  Uncertain Judgements: Eliciting Experts' Probabilities , 2006 .

[31]  F. Bass A new product growth model for consumer durables , 1976 .

[32]  Ken Stein,et al.  A comparison of two methods for expert elicitation in health technology assessments , 2016, BMC Medical Research Methodology.

[33]  S. Sullivan,et al.  Budget impact analysis-principles of good practice: report of the ISPOR 2012 Budget Impact Analysis Good Practice II Task Force. , 2014, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[34]  Frank M. Bass,et al.  A New Product Growth for Model Consumer Durables , 2004, Manag. Sci..

[35]  P. Goodwin,et al.  The challenges of pre-launch forecasting of adoption time series for new durable products , 2014 .