A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19 q 13
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L. Edwards | E. Regan | D. DeMeo | J. Hokanson | T. Beaty | B. Make | E. Silverman | J. Crapo | A. Gulsvik | B. Celli | J. Vestbo | P. Bakke | M. Cho | C. Hersh | D. Lomas | X. Kong | A. Agustí | E. Wouters | H. Coxson | W. MacNee | J. Yates | S. Rennard | A. Litonjua | R. Tal-Singer | C. Lange | P. Castaldi | P. Calverley | B. Himes | E. Wan | M. Siedlinski | J. Sylvia | B. Klanderman | J. Ziniti | D. Sparrow | J. Hetmanski | S. Pillai | W. Anderson | C. Crim | Tanda Murray | D. Demeo | W. Macnee | Xiangyang Kong
[1] F. Martinez,et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. , 2007, American journal of respiratory and critical care medicine.
[2] Per Magne Ueland,et al. Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC , 2011, Cancer Epidemiology, Biomarkers & Prevention.
[3] L. Bierut,et al. The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European–Americans , 2011, Pharmacogenetics and genomics.
[4] P. Sham,et al. Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases , 2011, Genetic epidemiology.
[5] J. Hokanson,et al. Genome-wide association study of smoking behaviours in patients with COPD , 2012 .
[6] N. Mehta. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. , 2011, Circulation. Cardiovascular genetics.
[7] Eleazar Eskin,et al. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. , 2011, American journal of human genetics.
[8] D. Postma,et al. Opportunities and Challenges in the Genetics of COPD 2010: An International COPD Genetics Conference Report , 2011, COPD.
[9] G. Gamble,et al. Individual and Cumulative Effects of GWAS Susceptibility Loci in Lung Cancer: Associations after Sub-Phenotyping for COPD , 2011, PloS one.
[10] K. Morgan,et al. The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study , 2011, BMC Medical Genetics.
[11] E. Regan,et al. Genetic Epidemiology of COPD (COPDGene) Study Design , 2011, COPD.
[12] G. Gamble,et al. Chromosome 4q31 locus in COPD is also associated with lung cancer , 2010, European Respiratory Journal.
[13] G. Abecasis,et al. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes , 2010, Genetic epidemiology.
[14] Jiaquan Xu,et al. Deaths: preliminary data for 2008. , 2010, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.
[15] D. Altshuler,et al. A map of human genome variation from population-scale sequencing , 2010, Nature.
[16] William Wheeler,et al. Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD , 2010, PLoS genetics.
[17] Christopher I. Amos,et al. Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5‐A3 genetic locus and lung cancer risk , 2010, Cancer.
[18] Michael Boehnke,et al. LocusZoom: regional visualization of genome-wide association scan results , 2010, Bioinform..
[19] Yun Li,et al. METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..
[20] Ayellet V. Segrè,et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis , 2010, Nature Genetics.
[21] C. Gieger,et al. Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior , 2010, Nature Genetics.
[22] Inês Barroso,et al. Genome-wide association study identifies five loci associated with lung function , 2010, Nature Genetics.
[23] Ming D. Li,et al. Genome-wide meta-analyses identify multiple loci associated with smoking behavior , 2010, Nature Genetics.
[24] A. Gulsvik,et al. Case–control studies on risk factors for chronic obstructive pulmonary disease: how does the sampling of the cases and controls affect the results? , 2010, The clinical respiratory journal.
[25] Marc Decramer,et al. The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema. , 2010, American journal of respiratory and critical care medicine.
[26] Christoph Lange,et al. Variants in FAM13A are associated with chronic obstructive pulmonary disease , 2010, Nature Genetics.
[27] Byron C. Wallace,et al. The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. , 2009, Human molecular genetics.
[28] A. Hofman,et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function , 2010, Nature Genetics.
[29] A. Hofman,et al. Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study , 2009, European Respiratory Journal.
[30] K. Holland,et al. Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development. , 2009, American journal of human genetics.
[31] D. DeMeo,et al. Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. , 2009, American journal of human genetics.
[32] P. Visscher,et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder , 2009, Nature.
[33] R. Tyndale,et al. A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo , 2009, The Pharmacogenomics Journal.
[34] D. Mannino,et al. The natural history of chronic airflow obstruction revisited: an analysis of the Framingham offspring cohort. , 2009, American journal of respiratory and critical care medicine.
[35] H. O'brodovich,et al. Global and gene-specific translational regulation in rat lung development. , 2009, American journal of respiratory cell and molecular biology.
[36] K. Shianna,et al. A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci , 2009, PLoS genetics.
[37] Scott T. Weiss,et al. A Genome-Wide Association Study of Pulmonary Function Measures in the Framingham Heart Study , 2009, PLoS genetics.
[38] Andrew D. Johnson,et al. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap , 2008, Bioinform..
[39] Maarit Tiirikainen,et al. Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine. , 2008, Cancer research.
[40] G. Gamble,et al. Lung cancer gene associated with COPD: triple whammy or possible confounding effect? , 2008, European Respiratory Journal.
[41] Manuel A. R. Ferreira,et al. Practical aspects of imputation-driven meta-analysis of genome-wide association studies. , 2008, Human molecular genetics.
[42] Yasutaka Nakano,et al. Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. , 2008, American journal of respiratory and critical care medicine.
[43] R. Tyndale,et al. Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent , 2008, Human mutation.
[44] A. Bosserhoff,et al. Misexpression of MIA disrupts lung morphogenesis and causes neonatal death. , 2008, Developmental biology.
[45] W. MacNee,et al. Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) , 2008, European Respiratory Journal.
[46] J. Maurer. Genetic Association Analysis of Functional Impairment in Chronic Obstructive Pulmonary Disease , 2008 .
[47] Zhaohui S. Qin,et al. A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.
[48] D. Mannino,et al. International variation in the prevalence of COPD (The BOLD Study): a population-based prevalence study , 2007, The Lancet.
[49] Manuel A. R. Ferreira,et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.
[50] Yurii S. Aulchenko,et al. BIOINFORMATICS APPLICATIONS NOTE doi:10.1093/bioinformatics/btm108 Genetics and population analysis GenABEL: an R library for genome-wide association analysis , 2022 .
[51] M. Post,et al. Hypoxia-inducible Factors in the First Trimester Human Lung , 2007, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[52] C. Strange,et al. Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiency , 2007, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.
[53] Edwin K Silverman,et al. The SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populations. , 2006, American journal of respiratory and critical care medicine.
[54] D. Reich,et al. Population Structure and Eigenanalysis , 2006, PLoS genetics.
[55] J Vestbo,et al. Developing COPD: a 25 year follow up study of the general population , 2006, Thorax.
[56] D. Reich,et al. Principal components analysis corrects for stratification in genome-wide association studies , 2006, Nature Genetics.
[57] Thomas A Trikalinos,et al. Family-Based versus Unrelated Case-Control Designs for Genetic Associations , 2006, PLoS genetics.
[58] E. Silverman,et al. A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease. , 2005, American journal of respiratory cell and molecular biology.
[59] N. Anthonisen,et al. The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial , 2005 .
[60] N. Laird,et al. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. , 2005, American journal of respiratory cell and molecular biology.
[61] Neal L. Benowitz,et al. Metabolism and Disposition Kinetics of Nicotine , 2005, Pharmacological Reviews.
[62] Aravinda Chakravarti,et al. Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies , 2004, Nature Genetics.
[63] Christoph Lange,et al. PBAT: tools for family-based association studies. , 2004, American journal of human genetics.
[64] Steven Piantadosi,et al. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. , 2003, The New England journal of medicine.
[65] E. Silverman,et al. Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease. , 2003, Human molecular genetics.
[66] J. Otte,et al. Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer. , 2002, Genes & development.
[67] N. Wareham,et al. Siblings of Patients with Severe Chronic Obstructive Pulmonary Disease Have a Significant Risk of Airflow Obstruction , 2002 .
[68] E. Silverman,et al. Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes. , 2002, Human molecular genetics.
[69] E. Silverman. Genetic Epidemiology of COPD. , 2002, Chest.
[70] 张锺儒,et al. 对急性哮喘加剧的成年患者两种不同教育干预的评价[英]/Co^^té J…∥Am J Respir Crit Care Med , 2002 .
[71] J. Twisk,et al. Is calculating pack-years retrospectively a valid method to estimate life-time tobacco smoking? A comparison between prospectively calculated pack-years and retrospectively calculated pack-years. , 2001, Addiction.
[72] R. Tyndale,et al. Duplications and defects in the CYP2A6 gene: identification, genotyping, and in vivo effects on smoking. , 2000, Molecular pharmacology.
[73] K. Roeder,et al. Genomic Control for Association Studies , 1999, Biometrics.
[74] A. Buist,et al. Effects of randomized assignment to a smoking cessation intervention and changes in smoking habits on respiratory symptoms in smokers with early chronic obstructive pulmonary disease: the Lung Health Study. , 1999, The American journal of medicine.
[75] G. Coetzee,et al. Genetic variation of CYP2A6, smoking, and risk of cancer , 1999, The Lancet.
[76] B Rosner,et al. Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis. , 1998, American journal of respiratory and critical care medicine.
[77] N. Caporaso,et al. Genetic susceptibility testing in smoking-cessation treatment: one-year outcomes of a randomized trial. , 1997, Addictive behaviors.
[78] N Risch,et al. The Future of Genetic Studies of Complex Human Diseases , 1996, Science.
[79] Y. Funae,et al. Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes. , 1996, The Journal of pharmacology and experimental therapeutics.
[80] E. Arnesen,et al. Smoking, serum lipids, blood pressure, and sex differences in myocardial infarction. A 12-year follow-up of the Finnmark Study. , 1996, Circulation.
[81] W. Bailey,et al. Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. , 1995, JAMA.
[82] W. Bailey,et al. Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1 , 1994 .
[83] M. Lebowitz,et al. Quantitative relationships between cigarette smoking and ventilatory function. , 1977, The American review of respiratory disease.
[84] Albert Damon,et al. The Normative Aging Study: An Interdisciplinary and Longitudinal Study of Health and Aging , 1972 .
[85] R. K. Larson,et al. The familial occurrence of chronic obstructive pulmonary disease. , 1965, Annals of internal medicine.