A robust small-molecule microarray platform for screening cell lysates.

[1]  A. Tanaka [A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase]. , 2007, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

[2]  Thomas Kodadek,et al.  Protein "fingerprinting" in complex mixtures with peptoid microarrays. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Myung-Ryul Lee,et al.  Facile preparation of carbohydrate microarrays by site-specific, covalent immobilization of unmodified carbohydrates on hydrazide-coated glass slides. , 2005, Organic letters.

[4]  Stuart L Schreiber,et al.  Small molecules: the missing link in the central dogma , 2005, Nature chemical biology.

[5]  John A. Tallarico,et al.  Small-molecule diversity using a skeletal transformation strategy. , 2005, Organic letters.

[6]  H. Seliger,et al.  Ultrathin functional star PEG coatings for DNA microarrays. , 2005, Biomacromolecules.

[7]  I. Shin,et al.  Fabrication of chemical microarrays by efficient immobilization of hydrazide-linked substances on epoxide-coated glass surfaces. , 2005, Angewandte Chemie.

[8]  Stuart L Schreiber,et al.  Convergent diversity-oriented synthesis of small-molecule hybrids. , 2005, Angewandte Chemie.

[9]  S. Schreiber,et al.  A library of spirooxindoles based on a stereoselective three-component coupling reaction. , 2004, Journal of the American Chemical Society.

[10]  Stuart L Schreiber,et al.  A synthesis strategy yielding skeletally diverse small molecules combinatorially. , 2004, Journal of the American Chemical Society.

[11]  Jennifer L. Harris,et al.  PNA-encoded protease substrate microarrays. , 2004, Chemistry & biology.

[12]  Xuan Huang,et al.  Microarrays of tagged combinatorial triazine libraries in the discovery of small-molecule ligands of human IgG. , 2004, Journal of combinatorial chemistry.

[13]  S. Schreiber,et al.  Modular synthesis and preliminary biological evaluation of stereochemically diverse 1,3-dioxanes. , 2004, Chemistry & biology.

[14]  A water-stable protected isocyanate glass array substrate. , 2004, Analytical biochemistry.

[15]  Herbert Waldmann,et al.  Staudinger ligation: a new immobilization strategy for the preparation of small-molecule arrays. , 2003, Angewandte Chemie.

[16]  H. Osada,et al.  Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions. , 2003, Angewandte Chemie.

[17]  Stuart L Schreiber,et al.  Generating Diverse Skeletons of Small Molecules Combinatorially , 2003, Science.

[18]  Stuart L Schreiber,et al.  Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis. , 2003, Journal of the American Chemical Society.

[19]  Hua Tang,et al.  Studies on Repository Compound Stability in DMSO under Various Conditions , 2003, Journal of biomolecular screening.

[20]  S. Schreiber,et al.  Expanding the functional group compatibility of small-molecule microarrays: discovery of novel calmodulin ligands. , 2003, Angewandte Chemie.

[21]  Chi‐Huey Wong,et al.  Synthesis of sugar arrays in microtiter plate. , 2002, Journal of the American Chemical Society.

[22]  Stuart L Schreiber,et al.  Skeletal diversity via a branched pathway: efficient synthesis of 29 400 discrete, polycyclic compounds and their arraying into stock solutions. , 2002, Journal of the American Chemical Society.

[23]  K. B. Yoon,et al.  Diisocyanates as novel molecular binders for monolayer assembly of zeolite crystals on glass. , 2002, Chemical communications.

[24]  P. Schultz,et al.  Profiling protein function with small molecule microarrays , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[25]  Stuart L. Schreiber,et al.  Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays , 2002, Nature.

[26]  Milan Mrksich,et al.  Carbohydrate arrays for the evaluation of protein binding and enzymatic modification. , 2002, Chemistry & biology.

[27]  Shaoyi Liu,et al.  Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells , 2002, Nature Biotechnology.

[28]  L. Garrelly,et al.  Reactivity of organic isocyanates with nucleophilic compounds: amines; alcohols; thiols; oximes; and phenols in dilute organic solutions , 2001 .

[29]  S. Schreiber,et al.  Asymmetric Catalysis in Diversity-Oriented Organic Synthesis: Enantioselective Synthesis of 4320 Encoded and Spatially Segregated Dihydropyrancarboxamides We thank the National Institute of General Medical Sciences (GM-52067) for support of this research, and Dr. John Tallarico and Max Narovlyansky , 2001, Angewandte Chemie.

[30]  John A. Tallarico,et al.  An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics. , 2001, Journal of combinatorial chemistry.

[31]  S. Schreiber,et al.  Printing proteins as microarrays for high-throughput function determination. , 2000, Science.

[32]  Stuart L. Schreiber,et al.  Small-Molecule Microarrays: Covalent Attachment and Screening of Alcohol-Containing Small Molecules on Glass Slides , 2000 .

[33]  Stuart L. Schreiber,et al.  Printing Small Molecules as Microarrays and Detecting Protein−Ligand Interactions en Masse , 1999 .

[34]  D. Holt,et al.  Synthesis and activity of bivalent FKBP12 ligands for the regulated dimerization of proteins. , 1998, Bioorganic & medicinal chemistry.

[35]  Jon Clardy,et al.  DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12. , 1994 .

[36]  A. Thiel,et al.  Direct fluorescence analysis of genetic polymorphisms by hybridization with oligonucleotide arrays on glass supports. , 1994, Nucleic acids research.

[37]  S. Schreiber,et al.  A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase , 1989, Nature.

[38]  Nolan H. Sigal,et al.  A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin , 1989, Nature.