Antibody Variable Regions

[1]  T. T. Wu,et al.  AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY , 1970, The Journal of experimental medicine.

[2]  E. Kabat,et al.  Construction of a three-dimensional model of the polypeptide backbone of the variable region of kappa immunoglobulin light chains. , 1972, Proceedings of the National Academy of Sciences of the United States of America.

[3]  E. Padlan,et al.  Variability of three-dimensional structure in immunoglobulins. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[4]  T. Wu,et al.  A predictive method for determining possible three-dimensional foldings of immunoglobulin backbones around antibody combining sites. , 1981, Journal of theoretical biology.

[5]  A. Rees,et al.  Modelling of the combining sites of three anti‐lysozyme monoclonal antibodies and of the complex between one of the antibodies and its epitope. , 1986, The EMBO journal.

[6]  M. Karplus,et al.  Prediction of the folding of short polypeptide segments by uniform conformational sampling , 1987, Biopolymers.

[7]  Lutz Riechmann,et al.  Reshaping human antibodies for therapy , 1988, Nature.

[8]  A. Lesk,et al.  Conformations of immunoglobulin hypervariable regions , 1989, Nature.

[9]  B. L. Sibanda,et al.  Conformation of beta-hairpins in protein structures. A systematic classification with applications to modelling by homology, electron density fitting and protein engineering. , 1989, Journal of molecular biology.

[10]  A Tramontano,et al.  Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins. , 1990, Journal of molecular biology.

[11]  P. Kraulis.  A program to produce both detailed and schematic plots of protein structures , 1991 .

[12]  A. Henry,et al.  Antibody modeling: Beyond homology , 1992 .

[13]  A M Lesk,et al.  Structural repertoire of the human VH segments. , 1992, Journal of molecular biology.

[14]  A. Lesk,et al.  The structural repertoire of the human V kappa domain. , 1995, The EMBO journal.

[15]  D T Jones,et al.  Protein fold recognition by sequence threading: tools and assessment techniques , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[16]  A. Lesk,et al.  Standard conformations for the canonical structures of immunoglobulins. , 1997, Journal of molecular biology.

[17]  E A Merritt,et al.  Raster3D: photorealistic molecular graphics. , 1997, Methods in enzymology.

[18]  M. Sternberg,et al.  Automated classification of antibody complementarity determining region 3 of the heavy chain (H3) loops into canonical forms and its application to protein structure prediction. , 1998, Journal of molecular biology.

[19]  T. N. Bhat,et al.  The Protein Data Bank , 2000, Nucleic Acids Res..

[20]  A R Rees,et al.  WAM: an improved algorithm for modelling antibodies on the WEB. , 2000, Protein engineering.