Analog layout synthesis: what's missing?

In the first decade of the twenty first century, the first generation of analog synthesis tools -- for sizing and for physical design -- moved from academic research projects, to startups, to integration on various standard platforms. In this talk I'll try to summarize what we got right in that first generation effort, but more importantly, what we got wrong. I'll talk in particular about usage models -- how real people do real layouts in this business -- and highlight what I think are the big gaps, the big problems, and the big opportunities.