The controversy between Golgi’s reticularism and Cajal’s neuronism, considered one of the great storms of ideas in the evolution of biological thought, finally had a positive influence on the development of neurobiology. Golgi was a committed reticularist, but invented a method of staining neurons that helped Cajal make a convincing case for the neuron doctrine. It is one of the most famous ironies that Golgi developed his revolutionary silver-based stain, which Cajal exploited so sufficiently against him. The debate between Golgi and Cajal was a heroic battle in which Golgi, too headstrong and too conservative, clung to his own theory until his death. The neurosciences have seen their share of impassioned conceptual duality in the matter of reticularism vs. neuronism. Cajal commented on the shared Nobel Prize, “what a cruel irony of fate of pair, like Siamese twins united by the shoulders, scientific adversaries of such contrasting character.” Is this book worthwhile for neurosurgeons? I think it is. The book stimulates the reader’s imagination, bringing him in at the dawn of a fascinating branch of the discipline of neuroscience, and serves as an excellent introduction and references source. This reviewer strongly recommends the book to neurosurgeons, residents, and medical students who are interested in the scientific underpinning of our specialty.