Supramolecular colloidosomes: fabrication, characterisation and triggered release of cargo.

We report a one-step method of assembling supramolecular colloidosomes at the interface of microfluidic droplets. The self-assembly process utilises a versatile CB[8] host-guest system to reversibly crosslink polystyrene nanoparticles via a polyacrylamide linker. These micrometre-sized hollow structures can be loaded with water-soluble cargo during formation, which can then undergo triggered release.

[1]  W. Raub From the National Institutes of Health. , 1990, JAMA.

[2]  M. Vendruscolo,et al.  Cucurbit[8]uril and blue-box: high-energy water release overwhelms electrostatic interactions. , 2013, Journal of the American Chemical Society.

[3]  N. He,et al.  Colloidosomes constructed by the seamless connection of nanoparticles: a mobile and recyclable strategy to intelligent capsules , 2011 .

[4]  S. Armes,et al.  Covalently Cross-Linked Colloidosomes , 2010 .

[5]  D. Weitz,et al.  Self-assembled shells composed of colloidal particles: fabrication and characterization. , 2005, Langmuir : the ACS journal of surfaces and colloids.

[6]  R. K. Shah,et al.  Monodisperse stimuli-responsive colloidosomes by self-assembly of microgels in droplets. , 2010, Langmuir : the ACS journal of surfaces and colloids.

[7]  Jing Zhang,et al.  One-Step Fabrication of Supramolecular Microcapsules from Microfluidic Droplets , 2012, Science.

[8]  Yoshinobu Nakamura,et al.  Formation of Pickering emulsions stabilized via interaction between nanoparticles dispersed in aqueous phase and polymer end groups dissolved in oil phase. , 2012, Langmuir : the ACS journal of surfaces and colloids.

[9]  Kimoon Kim,et al.  Selective Inclusion of a Hetero-Guest Pair in a Molecular Host: Formation of Stable Charge-Transfer Complexes in Cucurbit[8]uril. , 2001, Angewandte Chemie.

[10]  A. Hitchcock,et al.  Composite Tectocapsules Containing Porous Polymer Microspheres as Release Gates , 2005 .

[11]  S. O. Lumsdon,et al.  Influence of Particle Wettability on the Type and Stability of Surfactant-Free Emulsions† , 2000 .

[12]  Oren A Scherman,et al.  Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils. , 2012, Journal of the American Chemical Society.

[13]  Kunio Furusawa,et al.  Assembly of Latex Particles by Using Emulsion Droplets as Templates. 1. Microstructured Hollow Spheres , 1996 .

[14]  A. R. Bausch,et al.  Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles , 2002, Science.

[15]  H. N. Yow,et al.  Release profiles of encapsulated actives from colloidosomes sintered for various durations. , 2009, Langmuir : the ACS journal of surfaces and colloids.

[16]  R. K. Shah,et al.  Fabrication of Monodisperse Thermosensitive Microgels and Gel Capsules in Microfluidic Devices Highlight Www.rsc.org/softmatter | Soft Matter , 2022 .

[17]  Charles Levy,et al.  To G. S. , 1936 .

[18]  A. Studart,et al.  Monodisperse functional colloidosomes with tailored nanoparticle shells. , 2011, Langmuir : the ACS journal of surfaces and colloids.

[19]  O. Cayre,et al.  Fabrication of novel colloidosome microcapsules with gelled aqueous cores , 2004 .

[20]  Jianfang Wang,et al.  Emulsion-templated liquid core-polymer shell microcapsule formation. , 2009, Langmuir : the ACS journal of surfaces and colloids.

[21]  Oren A Scherman,et al.  Supramolecular cross-linked networks via host-guest complexation with cucurbit[8]uril. , 2010, Journal of the American Chemical Society.

[22]  Jae Wook Lee,et al.  Cucurbituril homologues and derivatives: new opportunities in supramolecular chemistry. , 2003, Accounts of chemical research.

[23]  Aaas News,et al.  Book Reviews , 1893, Buffalo Medical and Surgical Journal.

[24]  C. Robinson,et al.  Correlating solution binding and ESI-MS stabilities by incorporating solvation effects in a confined cucurbit[8]uril system. , 2010, The journal of physical chemistry. B.