Case Report Penetrating Endplate Screw Fixation for Thoracolumbar Pathological Fracture of Diffuse Idiopathic Skeletal Hyperostosis

With the advancement of cancer treatment and minimally invasive surgery, the indications for surgery for metastatic spinal tumors are expanding. Di ff use idiopathic skeletal hyperostosis (DISH) is a nonin fl ammatory skeletal disease characterized by calci fi cation and ossi fi cation of ligaments and entheses. In Japan, the prevalence of DISH is increasing with its superaging society. The purpose of this article is to report a case of applying a novel screw technique for pathological fracture in a patient with DISH and spinal metastasis. An 80-year-old man with spinal metastasis presented with acute onset of severe back pain, and investigations revealed a fracture of a metastatic lesion in T10 – T12 in the range of DISH. We performed posterior fi xation with a percutaneous pedicle screw system using a penetrating endplate technique. The patient ’ s back pain improved, and he was able to mobilize with minimal assistance and survived for 8 months with a good quality of life. Spinal fracture accompanied by DISH sometimes occurs with severe instability because of injury across 3-column injury and its long lever arm. Spinal instability neoplastic score indicates instability of pathological fractures of spinal metastases but needs to be evaluated carefully when DISH is present. The prevalence of DISH is increasing in the elderly, and penetrating endplate screws can be an e ff ective option in posterior fusion surgery for patients with DISH and spinal metastases.

[1]  M. Ota,et al.  Posterior spinal fixation using penetrating endplate screws in patients with diffuse idiopathic skeletal hyperostosis-related thoracolumbar fractures. , 2021, Journal of neurosurgery. Spine.

[2]  N. Mashima,et al.  Association Between Vertebral Fracture and Diffuse Idiopathic Skeletal Hyperostosis. , 2019, Spine.

[3]  Y. Tokuhashi,et al.  Therapeutic Impact of Percutaneous Pedicle Screw Fixation on Palliative Surgery for Metastatic Spine Tumors , 2019, Indian journal of orthopaedics.

[4]  Tetsuro Ohba,et al.  Spinal fractures in patients with Diffuse idiopathic skeletal hyperostosis:A nationwide multi-institution survey. , 2019, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[5]  Osahiko Tsuji,et al.  Spinal fractures in patients with diffuse idiopathic skeletal hyperostosis: Clinical characteristics by fracture level. , 2019, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[6]  M. Bilsky,et al.  State of the Art Treatment of Spinal Metastatic Disease , 2018, Neurosurgery.

[7]  H. Katoh,et al.  Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) assessed with whole-spine computed tomography in 1479 subjects , 2018, BMC Musculoskeletal Disorders.

[8]  Katsuhisa Kawanami,et al.  The prevalence of diffuse idiopathic skeletal hyperostosis in Japan - the first report of measurement by CT and review of the literature. , 2016, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[9]  A. Lizaur-Utrilla,et al.  Transdiscal screw versus pedicle screw fixation for high-grade L5-S1 isthmic spondylolisthesis in patients younger than 60 years: a case–control study , 2016, European Spine Journal.

[10]  N. Theodore,et al.  Biomechanics of transvertebral screw fixation in the thoracic spine: an in vitro study. , 2016, Journal of neurosurgery. Spine.

[11]  Kozo Nakamura,et al.  Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study , 2015, Journal of Bone and Mineral Metabolism.

[12]  T. Asazuma,et al.  Cortical bone trajectory for lumbosacral fixation: penetrating S-1 endplate screw technique: technical note. , 2014, Journal of neurosurgery. Spine.

[13]  R. Mobbs,et al.  Minimally Invasive Percutaneous Fixation Techniques for Metastatic Spinal Disease , 2014, Orthopaedic surgery.

[14]  R. Okada,et al.  New prognostic factors and scoring system for patients with skeletal metastasis , 2014, Cancer medicine.

[15]  W. Dhert,et al.  Clinical outcome after traumatic spinal fractures in patients with ankylosing spinal disorders compared with control patients. , 2014, The spine journal : official journal of the North American Spine Society.

[16]  Stephen M Pirris,et al.  Placement of thoracic transvertebral pedicle screws using 3D image guidance. , 2013, Journal of neurosurgery. Spine.

[17]  L. Rhines,et al.  Spine Metastasis , 2011, International journal of surgical oncology.

[18]  J. Chapman,et al.  Spine Fractures in Patients With Ankylosing Spinal Disorders , 2010, Spine.

[19]  F. Oner,et al.  Spinal fractures in patients with ankylosing spinal disorders: a systematic review of the literature on treatment, neurological status and complications , 2009, European Spine Journal.

[20]  M. Penas-Prado,et al.  Spinal cord compression in cancer patients: Review of diagnosis and treatment , 2008, Current oncology reports.

[21]  H. Matsuzaki,et al.  A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. , 2002, Spine.

[22]  W. Hutton,et al.  Transdiscal L5–S1 Screws for the Fixation of Isthmic Spondylolisthesis: A Biomechanical Evaluation , 2003, Journal of spinal disorders & techniques.

[23]  W. Abdu,et al.  Pedicular transvertebral screw fixation of the lumbosacral spine in spondylolisthesis. A new technique for stabilization. , 1994, Spine.

[24]  J. Robins,et al.  Diffuse idiopathic skeletal hyperostosis (DISH): Forestier's disease with extraspinal manifestations. , 1975, Radiology.

[25]  J. Forestier,et al.  Senile Ankylosing Hyperostosis of the Spine * , 1950, Annals of the rheumatic diseases.