CHAPTER 11 – Locus Coeruleus, A5 and A7 Noradrenergic Cell Groups

[1]  V. Pickel,et al.  Input from central nucleus of the amygdala efferents to pericoerulear dendrites, some of which contain tyrosine hydroxylase immunoreactivity , 1996 .

[2]  F. M. Clark,et al.  The noradrenergic innervation of the spinal cord: differences between two substrains of Sprague-Dawley rats determined using retrograde tracers combined with immunocytochemistry , 1991, Neuroscience Letters.

[3]  G. Aston-Jones,et al.  Use of pseudorabies virus to delineate multisynaptic circuits in brain: opportunities and limitations , 2000, Journal of Neuroscience Methods.

[4]  G. Aghajanian,et al.  ACh, substance P and met-enkephalin in the locus coeruleus: pharmacological evidence for independent sites of action. , 1979, European journal of pharmacology.

[5]  J. Morrison,et al.  The intra-cortical trajectory of the coeruleo-cortical projection in the rat: A tangentially organized cortical afferent , 1981, Neuroscience.

[6]  Gary Aston-Jones,et al.  Activation of locus coeruleus by prefrontal cortex is mediated by excitatory amino acid inputs , 1997, Brain Research.

[7]  S. Snyder,et al.  Enkephalin convertase localization by [3H]guanidinoethylmercaptosuccinic acid autoradiography: selective association with enkephalin-containing neurons. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[8]  B. Jacobs,et al.  Systemic naloxone administration potentiates locus coeruleus noradrenergic neuronal activity under stressful but not non-stressful conditions , 1988, Brain Research.

[9]  U. Ungerstedt Stereotaxic mapping of the monoamine pathways in the rat brain. , 1971, Acta physiologica Scandinavica. Supplementum.

[10]  Robert Elde,et al.  Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: enkephalin and substance P , 1977 .

[11]  P. Guyenet,et al.  Afferent and efferent connections of the A5 noradrenergic cell group in the rat , 1987, The Journal of comparative neurology.

[12]  G. Aghajanian,et al.  Evidence for norepinephrine-mediated collateral inhibition of locus coeruleus neurons , 1977, Brain Research.

[13]  S. Foote,et al.  Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus , 1983, Brain Research.

[14]  A. Weindl,et al.  Distribution of NT-IR perikarya in the brain of the guinea pig with special reference to cardiovascular centers in the medulla oblongata , 2004, Histochemistry.

[15]  G. Aghajanian,et al.  Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides , 1977, Brain Research.

[16]  J. Chalmers,et al.  Simultaneous demonstration of phenylethanolamine N-methyltransferase immunofluorescent and catecholamine fluorescent nerve cell bodies in the rat medulla oblongata , 1980, Neuroscience.

[17]  G. Aston-Jones,et al.  Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system , 1999, The Journal of comparative neurology.

[18]  S. Snyder,et al.  Opiate receptor: autoradiographic localization in rat brain. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[19]  F. Bloom,et al.  Corticotropin releasing factor (CRF): immunoreactive neurones and fibers in rat hypothalamus , 1982, Regulatory Peptides.

[20]  S. Palay,et al.  The nucleus paragigantocellularis lateralis in the rat , 1981, Anatomy and Embryology.

[21]  Dennis A. Steindler,et al.  Locus coerules neurons have axons that branch to the forebrain and cerebellum , 1981, Brain Research.

[22]  K. Fuxe,et al.  On the projections from the locus coeruleus noradrealine neurons: the cerebellar innervation. , 1971, Brain research.

[23]  G. Aston-Jones,et al.  GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[24]  S. Paul,et al.  Tyrosine hydroxylase and galanin mRNA levels in locus coeruleus neurons are increased following reserpine administration , 1990, Synapse.

[25]  J. Fritschy,et al.  Distribution of locus coeruleus axons within the rat brainstem demonstrated by Phaseolus vulgaris leucoagglutinin anterograde tracing in combination with dopamine‐β‐hydroxylase immunofluorescence , 1990, The Journal of comparative neurology.

[26]  F E Bloom,et al.  The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Molliver,et al.  The locus coeruleus in the rat: An immunohistochemical delineation , 1980, Neuroscience.

[28]  Claus Pfister,et al.  Fluoreszenzhistochemische und neurohistologische Untersuchungen am Locus coeruleus der Ratte , 1980 .

[29]  R. Clavier Afferent projections to the self-stimulation regions of the dorsal pons, including the locus coeruleus, in the rat as demonstrated by the horseradish peroxidase technique , 1979, Brain Research Bulletin.

[30]  M Ennis,et al.  Activation of Locus Coeruleus Enhances the Responses of Olfactory Bulb Mitral Cells to Weak Olfactory Nerve Input , 1996, The Journal of Neuroscience.

[31]  K. Thor,et al.  Immunohistochemical and biochemical analysis of serotonin and substance P colocalization in the nucleus tractus solitarii and associated afferent ganglia of the rat , 1988, Synapse.

[32]  C. Saper,et al.  Spinal and trigeminal dorsal horn projections to the parabrachial nucleus in the rat , 1985, The Journal of comparative neurology.

[33]  Charles J. Wilson,et al.  Fine structure of rat locus coeruleus , 1980, The Journal of comparative neurology.

[34]  R. L. McBride,et al.  Neonatal 6‐hydroxydopamine destroys spinal cord noradrenergic axons from the locus coeruleus, but not those from lateral tegmental cell groups , 1985, The Journal of comparative neurology.

[35]  S. Hunt,et al.  The distribution of serotonin, met-enkephalin and β-lipotropin-like immunoreactivity in neuronal perikarya of the cat brainstem , 1982, Neuroscience Letters.

[36]  C. Saper,et al.  Effect of Lesions of the Ventrolateral Preoptic Nucleus on NREM and REM Sleep , 2000, The Journal of Neuroscience.

[37]  G. Mogenson,et al.  Electrophysiological identification of neurons in locus coeruleus , 1976, Experimental Neurology.

[38]  K. Satoh,et al.  Divergent projections of catecholamine neurons of the locus coeruleus as revealed by fluorescent retrograde double labeling technique , 1981, Neuroscience Letters.

[39]  A. Weindl,et al.  Substance P-immunoreactive neurons in the brainstem of the cat related to cardiovascular centers , 2004, Cell and Tissue Research.

[40]  N. Kojima,et al.  Immunohistochemical studies on GABAergic neurons in the rat locus coeruleus, with special reference to their relationship to astrocytes. , 1987, Acta anatomica.

[41]  P. Hof,et al.  Autoradiographic mapping of [mono[125I]iodo-Tyr10, MetO17]vasoactive intestinal peptide binding sites in the rat brain , 1987, Neuroscience.

[42]  Pat Levitt,et al.  Origin and organization of brainstem catecholamine innervation in the rat , 1979, The Journal of comparative neurology.

[43]  J. Fallon,et al.  Distribution of dynorphin and enkephalin peptides in the rat brain , 1986, The Journal of comparative neurology.

[44]  J. Rossier,et al.  Evidence for synenkephalin-like immunoreactivity in pontobulbar monoaminergic neurons of the cat , 1985, Brain Research.

[45]  E. V. Bockstaele Multiple substrates for serotonergic modulation of rat locus coeruleus neurons and relationships with kainate receptors , 2000, Brain Research Bulletin.

[46]  M. Ishimatsu,et al.  Synchronous Activity in Locus Coeruleus Results from Dendritic Interactions in Pericoerulear Regions , 1996, The Journal of Neuroscience.

[47]  D. Jacobowitz,et al.  Immunocytochemical localization of peptides and other neurochemicals in the rat laterodorsal tegmental nucleus and adjacent area , 1988, The Journal of comparative neurology.

[48]  K. Fuxe,et al.  Further mapping out of central noradrenaline neuron systems: projections of the "subcoeruleus" area. , 1972, Brain research.

[49]  M. Page,et al.  Activation of noradrenergic locus coeruleus neurons by hemodynamic stress is due to local release of corticotropin-releasing factor , 1991, Brain Research.

[50]  M. Hamon,et al.  Localization of met-enkephalin-like immunoreactivity within pain-related nuclei of cervical spinal cord, brainstem and midbrain in the cat , 1983, Brain Research Bulletin.

[51]  F. Bloom,et al.  Efferent projections of nucleus locus coeruleus: Topographic organization of cells of origin demonstrated by three-dimensional reconstruction , 1986, Neuroscience.

[52]  S. A. Shefner,et al.  GABAA and GABAB receptors and the ionic mechanisms mediating their effects on locus coeruleus neurons. , 1991, Progress in brain research.

[53]  T. O'donohue,et al.  The distribution of corticotropin releasing factor-like immunoreactive neurons in rat brain , 1982, Peptides.

[54]  G. Aston-Jones,et al.  Characterization of transsynaptic tracing with central application of pseudorabies virus , 1999, Brain Research.

[55]  M. Christie,et al.  Electrical coupling synchronizes subthreshold activity in locus coeruleus neurons in vitro from neonatal rats , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[56]  James N. Davis,et al.  Topography of locus ceruleus neurons projecting to the area dentata , 1983, Experimental Neurology.

[57]  E. V. Van Bockstaele,et al.  Functional Coupling between Neurons and Glia , 2000, The Journal of Neuroscience.

[58]  S. Bloom,et al.  Orexins: effects on behavior and localisation of orexin receptor 2 messenger ribonucleic acid in the rat brainstem , 2001, Brain Research.

[59]  V. Pickel,et al.  δ‐opioid receptor is present in presynaptic axon terminals in the rat nucleus locus coeruleus: Relationships with methionine5‐enkephalin , 1997 .

[60]  A. Schally,et al.  Immunocytochemical localization of corticotropin-releasing factor (CRF) in the rat brain. , 1982, The American journal of anatomy.

[61]  C. Phelix,et al.  Monoamine innervation of bed nucleus of stria terminalis: An electron microscopic investigation , 1992, Brain Research Bulletin.

[62]  C. Saper,et al.  Efferent projections of the infralimbic cortex of the rat , 1991, The Journal of comparative neurology.

[63]  S. Nakamura,et al.  Duration-dependent effects of repeated restraint stress on cortical projections of locus coeruleus neurons , 1990, Neuroscience Letters.

[64]  M. Sato,et al.  An immunocytochemical study using the PAP method for tyrosine hydroxylase and serotonin in alternate sections, and in situ hybridization to detect tryptophan hydroxylase mRNA in the rat's locus ceruleus. , 1991, Acta histochemica.

[65]  G. Aston-Jones,et al.  Evidence for divergent projections to the brain noradrenergic system and the spinal parasympathetic system from Barrington's nucleus , 1996, Brain Research.

[66]  J. Pujol,et al.  The efferent connections of the nucleus raphe centralis superior in the rat as revealed by radioautography , 1979, Brain Research.

[67]  R. Buijs,et al.  Monoaminergic fibers form conventional synapses in the cerebral cortex , 1987, Neuroscience Letters.

[68]  R. Grzanna,et al.  Noradrenergic neurons with divergent projections to the motor trigeminal nucleus and the spinal cord: A double retrograde neuronal labeling study , 1988, Neuroscience.

[69]  T. Gray,et al.  The amygdalo-brainstem pathway: Selective innervation of dopaminergic, noradrenergic and adrenergic cells in the rat , 1989, Neuroscience Letters.

[70]  J. D. McGaugh,et al.  Reversible lesions of the nucleus of the solitary tract attenuate the memory-modulating effects of posttraining epinephrine. , 1993, Behavioral neuroscience.

[71]  J. Williams,et al.  Opioid inhibition in locus coeruleus. , 1995, Journal of neurophysiology.

[72]  K. Fuxe,et al.  EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS. , 1964, Acta physiologica Scandinavica. Supplementum.

[73]  Moore Ry,et al.  The distribution of dopamine-beta-hydroxylase, neuropeptide Y and galanin in locus coeruleus neurons. , 1989 .

[74]  S. Snyder,et al.  Neurotensin-containing cell bodies, fibers and nerve terminals in the brain stem of the rat: Immunohistochemical mapping , 1979, Brain Research.

[75]  J. Sievers,et al.  Morphological and biochemical studies on the ontogenesis of the nucleus locus coeruleus. , 1981, Bibliotheca anatomica.

[76]  R. Moore,et al.  Noradrenergic innervation of the adult rat hippocampal formation , 1980, The Journal of comparative neurology.

[77]  J. Morrison,et al.  The distribution and orientation of noradrenergic fibers in neocortex of the rat: An immunofluorescence study , 1978, The Journal of comparative neurology.

[78]  M. Tohyama,et al.  Noradrenaline innervation of the spinal cord studied by the horseradish peroxidase method combined with monoamine oxidase staining , 1977, Experimental Brain Research.

[79]  G. Papadopoulos,et al.  Distribution and synaptic organization of serotoninergic and noradrenergic axons in the lateral geniculate nucleus of the rat , 1990, The Journal of comparative neurology.

[80]  W. Young,et al.  Noradrenergic alpha 1 and alpha 2 receptors: light microscopic autoradiographic localization. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[81]  M Ennis,et al.  Dendrites of locus coeruleus neurons extend preferentially into two pericoerulear zones , 1996, The Journal of comparative neurology.

[82]  G. Aghajanian,et al.  Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane , 1976, Brain Research.

[83]  R. M. Bowker,et al.  Noradrenergic projections to the spinal cord of the rat , 1983, Brain Research.

[84]  K. Kitahama,et al.  Immunohistochemical evidence for the adrenergic medullary longitudinal bundle as a major ascending pathway to the locus coeruleus , 1987, Neuroscience Letters.

[85]  S. Inagaki,et al.  Ontogeny of neurotensin-containing neuron system of the rat: Immunohistochemical analysis—II. Lower brain stem , 1983, Neuroscience.

[86]  A. Craig,et al.  Association of spinal lamina I projections with brainstem catecholamine neurons in the monkey , 1996, Experimental Brain Research.

[87]  Peter Room,et al.  Divergent axon collaterals of rat locu Demonstration by a fluorescent double labeling technique , 1981, Brain Research.

[88]  R. Roth,et al.  Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin , 1989, The Journal of comparative neurology.

[89]  P. Sawchenko,et al.  Anatomical specificity of noradrenergic inputs to the paraventricular and supraoptic nuclei of the rat hypothalamus , 1988, The Journal of comparative neurology.

[90]  J. Coyle,et al.  Co‐localization of N‐acetyl‐aspartyl‐glutamate in central cholinergic, noradrenergic, and serotonergic neurons , 1987, Synapse.

[91]  K. Imamoto,et al.  Fine structure of the locus coeruleus in the rat. , 1970, Archivum histologicum Japonicum = Nihon soshikigaku kiroku.

[92]  T. Hökfelt,et al.  Coexistence of galanin-like immunoreactivity with catecholamines, 5- hydroxytryptamine, GABA and neuropeptides in the rat CNS , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[93]  J. Fallon,et al.  Catecholamine innervation of the basal forebrain II. Amygdala, suprarhinal cortex and entorhinal cortex , 1978, The Journal of comparative neurology.

[94]  T. Hökfelt,et al.  Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system , 1978, Neuroscience.

[95]  S. Sara,et al.  Inhibitory influence of frontal cortex on locus coeruleus neurons. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[96]  J. Williams,et al.  Dendritic arbor of locus coeruleus neurons contributes to opioid inhibition. , 1996, Journal of neurophysiology.

[97]  Cedric L. Williams,et al.  Posttraining Inactivation of Excitatory Afferent Input to the Locus Coeruleus Impairs Retention in an Inhibitory Avoidance Learning Task , 2000, Neurobiology of Learning and Memory.

[98]  O. Lindvall,et al.  The adrenergic innervation of the rat thalamus as revealed by the glyoxylic acid fluorescence method , 1974, The Journal of comparative neurology.

[99]  L. Descarries,et al.  Noradrenaline axon terminals in adult rat neocortex: An immunocytochemical analysis in serial thin sections , 1990, Neuroscience.

[100]  D. Woodward,et al.  The distribution of neocortical projection neurons in the locus coeruleus , 1983, The Journal of comparative neurology.

[101]  Pat Levitt,et al.  Noradrenaline neuron innervation of the neocortex in the rat , 1978, Brain Research.

[102]  G. Aston-Jones,et al.  Corticotropin-releasing factor innervation of the locus coeruleus region: Distribution of fibers and sources of input , 1992, Neuroscience.

[103]  V. Pickel,et al.  Ultrastructural Evidence for Prominent Distribution of the μ-Opioid Receptor at Extrasynaptic Sites on Noradrenergic Dendrites in the Rat Nucleus Locus Coeruleus , 1996, The Journal of Neuroscience.

[104]  S. Hellström,et al.  A new projection from locus coeruleus to the spinal ventral columns: histochemical and biochemical evidence , 1978, Brain Research.

[105]  J. Coyle,et al.  Ultrastructural demonstration of noradrenergic synapses in the rat central nervous system by dopamine-beta-hydroxylase immunocytochemistry. , 1981, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[106]  F. Bloom,et al.  Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle , 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[107]  J. Coyle,et al.  Visualization of central noradrenergic neurons in thick sections by the unlabeled antibody method: a transmitter-specific Golgi image. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[108]  E. Dietrichs Divergent axon collaterals to cerebellum and amygdala from neurons in the parabrachial nucleus, the nucleus locus coeruleus and some adjacent nuclei , 1985, Anatomy and Embryology.

[109]  E. V. Van Bockstaele,et al.  Amygdaloid Corticotropin‐Releasing Factor Targets Locus Coeruleus Dendrites: Substrate for the Co‐ordination of Emotional and Cognitive Limbs of the Stress Response , 1998, Journal of neuroendocrinology.

[110]  H. Olpe,et al.  Excitatory effects of ACTH on noradrenergic neurons of the locus coeruleus in the rat , 1982, Brain Research.

[111]  I. Merchenthaler,et al.  Corticotropin releasing factor (CRF)-like immunoreactivity in the rat central nervous system. Extrahypothalamic distribution , 1984, Peptides.

[112]  J. Roberts,et al.  Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord , 2001, Neuroscience.

[113]  F. Eckenstein,et al.  Colocalization of enkephalin-like and choline acetyltransferase-like immunoreactivities in olivocochlear neurons of the guinea pig. , 1984, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[114]  Hui-ling Liu,et al.  Noradrenergic neurons expressing substance P receptor (NK1) in the locus coeruleus complex: a double immunofluorescence study in the rat , 2000, Brain Research.

[115]  S. Foote,et al.  Distribution of dopamine β‐hydroxylase‐like immunoreactive fibers within the shell subregion of the nucleus accumbens , 1997, Synapse.

[116]  T. Gray,et al.  Organization of amygdaloid projections to brainstem dopaminergic, noradrenergic, and adrenergic cell groups in the rat , 1992, Brain Research Bulletin.

[117]  R. Grzanna,et al.  Noradrenergic projections to brainstem nuclei: Evidence for differential projections from noradrenergic subgroups , 1987, The Journal of comparative neurology.

[118]  Yan Zhu,et al.  A neural circuit for circadian regulation of arousal , 2001, Nature Neuroscience.

[119]  E. V. Bockstaele,et al.  Enkephalin terminals form inhibitory-type synapses on neurons in the rat nucleus locus coeruleus that project to the medial prefrontal cortex , 1996, Neuroscience.

[120]  R. North,et al.  Synaptic potentials in rat locus coeruleus neurones. , 1988, The Journal of physiology.

[121]  T. Hökfelt,et al.  Evidence for enkephalin immunoreactive neurons in the medulla oblongata projecting to the spinal cord , 1979, Neuroscience Letters.

[122]  G. Mogenson,et al.  A study of inputs to antidromically identified neurons of the locus coeruleus , 1977, Brain Research.

[123]  P. Guyenet The coeruleospinal noradrenergic neurons: Anatomical and electrophysiological studies in the rat , 1980, Brain Research.

[124]  B. Waterhouse,et al.  Topographic organization of rat locus coeruleus and dorsal raphe nuclei: Distribution of cells projecting to visual system structures , 1993, The Journal of comparative neurology.

[125]  T. Hökfelt,et al.  Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat , 1984, Neuroscience.

[126]  W. Cowan,et al.  An autoradiographic study of the efferent connections of the lateral hypothalamic area in the rat , 1979, The Journal of comparative neurology.

[127]  D. Amaral,et al.  The locus coeruleus: neurobiology of a central noradrenergic nucleus , 1977, Progress in Neurobiology.

[128]  D. Bajic,et al.  Projections of neurons in the periaqueductal gray to pontine and medullary catecholamine cell groups involved in the modulation of nociception , 1999, The Journal of comparative neurology.

[129]  Gary Aston-Jones,et al.  The iontophoretic application of Fluoro-Gold for the study of afferents to deep brain nuclei , 1988, Brain Research.

[130]  G. Aston-Jones,et al.  Adrenergic and non-adrenergic neurons in the C1 and C3 areas project to locus coeruleus: A fluorescent double labeling study , 1988, Neuroscience Letters.

[131]  G. Aston-Jones,et al.  Robust enkephalin innervation of the locus coeruleus from the rostral medulla , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[132]  Shoji Nakamura,et al.  Antidromic activation of the rat locus coeruleus neurons from hippocampus, cerebral and cerebellar cortices , 1975, Brain Research.

[133]  A. Loewy,et al.  Efferent projections of the A1 catecholamine cell group in the rat: An autoradiographic study , 1982, Brain Research.

[134]  F. Bloom,et al.  Proliferation of norepinephrine-containing axons in rat cerebellar cortex after peduncle lesions. , 1973, Brain research.

[135]  Virginia M. Pickel,et al.  A serotonergic innervation of noradrenergic neurons in nucleus locus coeruleus: Demonstration by immunocytochemical localization of the transmitter specific enzymes tyrosine and tryptophan hydroxylase , 1977, Brain Research.

[136]  E. V. Bockstaele,et al.  Anatomic basis for differential regulation of the rostrolateral peri–locus coeruleus region by limbic afferents , 1999, Biological Psychiatry.

[137]  K Fuxe,et al.  Distribution of noradrenaline nerve terminals in cortical areas of the rat. , 1968, Brain research.

[138]  S. Snyder,et al.  Immunohistochemical mapping of enkephalin containing cell bodies, fibers and nerve terminals in the brain stem of the rat , 1979, Brain Research.

[139]  G. Aston-Jones,et al.  Locus coeruleus and regulation of behavioral flexibility and attention. , 2000, Progress in brain research.

[140]  G. Aston-Jones,et al.  A potent excitatory input to the nucleus locus coeruleus from the ventrolateral medulla , 1986, Neuroscience Letters.

[141]  F E Bloom,et al.  Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems. , 1979, Annual review of neuroscience.

[142]  P. Kalivas,et al.  Neurotensin: Topographical distribution in rat brain by immunohistochemistry , 1982, The Journal of comparative neurology.

[143]  S. Sesack,et al.  Immunolocalization of the cocaine‐ and antidepressant‐sensitive l‐norepinephrine transporter , 2000, The Journal of comparative neurology.

[144]  G. Aghajanian,et al.  Excitation of locus coeruleus neurons by vasoactive intestinal peptide: evidence for a G-protein-mediated inward current , 1989, Brain Research.

[145]  M. Ennis,et al.  Direct excitation of mitral cells via activation of alpha1-noradrenergic receptors in rat olfactory bulb slices. , 2001, Journal of neurophysiology.

[146]  Jon T. Willie,et al.  To eat or to sleep? Orexin in the regulation of feeding and wakefulness. , 2001, Annual review of neuroscience.

[147]  T. Kemper,et al.  Nucleus locus coeruleus: A morphometric golgi study in rats of three age groups , 1982, Brain Research.

[148]  M. Bannon,et al.  Stress-induced c-fos expression in the rat locus coeruleus is dependent on neurokinin 1 receptor activation , 1999, Neuroscience.

[149]  S. T. Mason,et al.  Regional topography within noradrenergic locus coeruleus as revealed by retrograde transport of horseradish peroxidase , 1979, The Journal of comparative neurology.

[150]  M. Kuhar,et al.  Iontophoretic application of opiates to the locus coeruleus , 1977, Brain Research.

[151]  R. North,et al.  Opiate-receptor interactions on single locus coeruleus neurones. , 1984, Molecular pharmacology.

[152]  Laurent Descarries,et al.  Noradrenergic axon terminals in the cerebral cortex of rat. III. Topometric ultrastructural analysis , 1977, Brain Research.

[153]  R. Valentino,et al.  Evidence for Functional Release of Endogenous Opioids in the Locus Ceruleus during Stress Termination , 2001, The Journal of Neuroscience.

[154]  P. Mantyh,et al.  Neuropeptides are present in projection neurones at all levels in visceral and taste pathways: from periphery to sensory cortex , 1984, Brain Research.

[155]  T. Kaneko,et al.  Glutaminase-like immunoreactivity in the lower brainstem and cerebellum of the adult rat , 1989, Neuroscience.

[156]  G. Papadopoulos,et al.  Neurotensinlike immunoreactive neurons in the hedgehog (Erinaceus europaeus) and the sheep (Ovis aries) central nervous system , 1986, The Journal of comparative neurology.

[157]  M. Herkenham,et al.  Mismatches between neurotransmitter and receptor localizations in brain: observations and implications , 1987, Neuroscience.

[158]  M. Chat,et al.  Catecholaminergic and GABAergic anatomical relationship in the rat substantia nigra, locus coeruleus, and hypothalamic median eminence: immunocytochemical visualization of biosynthetic enzymes on serial semithin plastic-embedded sections. , 1984, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[159]  P. Groves,et al.  Monoaminergic presynaptic axons and dendrites in rat locus coeruleus seen in reconstructions of serial sections , 1980, The Journal of comparative neurology.

[160]  J. Storm-Mathisen,et al.  Glutamate‐ and GABA‐containing neurons in the mouse and rat brain, as demonstrated with a new immunocytochemical technique , 1984, The Journal of comparative neurology.

[161]  D. Reis,et al.  Newly identified GABAergic neurons in regions of the ventrolateral medulla which regulate blood pressure , 1985, Brain Research.

[162]  B J Hoffer,et al.  Norepinephrine mediated cerebellar synapses: a model system for neuropsychopharmacology. , 1972, Biological psychiatry.

[163]  H. Jelinek,et al.  Dye-coupling among neurons of the rat locus coeruleus during postnatal development , 1993, Neuroscience.

[164]  Randy D. Blakely,et al.  Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter , 1991, Nature.

[165]  Y. Kubota,et al.  Distribution of substance P-like immunoreactivity in the lower brainstem of the human fetus: An immunohistochemical study , 1982, Brain Research.

[166]  Michael Davis,et al.  The Extended Amygdala: Are the Central Nucleus of the Amygdala and the Bed Nucleus of the Stria Terminalis Differentially Involved in Fear versus Anxiety? , 1999, Annals of the New York Academy of Sciences.

[167]  Z. Liposits,et al.  Catecholamine-CRF synaptic interaction in a septal bed nucleus: Afferents of neurons in the bed nucleus of the stria terminalis , 1994, Brain Research Bulletin.

[168]  L. Descarries,et al.  Serotonin nerve terminals in the locus coeruleus of adult rat: A radioautographic study , 1978, Brain Research.

[169]  F. Bloom,et al.  Studies on norepinephrine-containing afferents to Purkinje cells of art cerebellum. I. Localization of the fibers and their synapses. , 1971, Brain research.

[170]  R C Lin,et al.  Lateralization and functional organization of the locus coeruleus projection to the trigeminal somatosensory pathway in rat , 1997, The Journal of comparative neurology.

[171]  J. Lipski,et al.  Noradrenaline transporter expression in the pons and medulla oblongata of the rat: localisation to noradrenergic and some C1 adrenergic neurones. , 1998, Brain research. Molecular brain research.

[172]  A. Loewy,et al.  Efferent connections of the ventral medulla oblongata in the rat , 1981, Brain Research Reviews.

[173]  G. Aghajanian,et al.  Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique , 1978, The Journal of comparative neurology.

[174]  E. V. Bockstaele,et al.  Electron microscopic evidence for coexistence of leucine5-enkephalin and γ-aminobutyric acid in a subpopulation of axon terminals in the rat locus coeruleus region , 1997, Brain Research.

[175]  L. Swanson,et al.  The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat , 1982, Brain Research Reviews.

[176]  Barbara E. Jones,et al.  Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study , 1977, Brain Research.

[177]  T. Kaneko,et al.  Immunohistochemical demonstration of glutaminase in catecholaminergic and serotoninergic neurons of rat brain , 1990, Brain Research.

[178]  G Chouvet,et al.  Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[179]  R. M. Bowker,et al.  Serotonergic and peptidergic projections to the spinal cord demonstrated by a combined retrograde HRP histochemical and immunocytochemical staining method , 1981, Brain Research.

[180]  G. Aston-Jones,et al.  Adrenergic innervation of the rat nucleus locus coeruleus arises predominantly from the C1 adrenergic cell group in the rostral medulla , 1991, Neuroscience.

[181]  F. Bloom,et al.  Nonrepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli , 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[182]  D. Reis,et al.  Ultrastructural localization of phenylethanolamine N-methyltransferase-like immunoreactivity in the rat locus coeruleus , 1989, Brain Research.

[183]  G. Raisman,et al.  Muscarinic receptors in the central nervous system of the rat. II. Distribution of binding of [3H]propylbenzilylcholine mustard in the midbrain and hindbrain , 1979, Brain Research Reviews.

[184]  P. Branchereau,et al.  Morphologically heterogeneous met‐enkephalin terminals form synapses with tyrosine hydroxylase‐containing dendrites in the rat nucleus locus coeruleus , 1995, The Journal of comparative neurology.

[185]  J. Morrison,et al.  Noradrenergic innervation of cerebral cortex: widespread effects of local cortical lesions. , 1979, Science.

[186]  E. V. Van Bockstaele,et al.  Ultrastructural evidence for prominent postsynaptic localization of α2C‐adrenergic receptors in catecholaminergic dendrites in the rat nucleus locus coeruleus , 1998, The Journal of comparative neurology.

[187]  S. Carr,et al.  Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior , 1998, Cell.

[188]  L. Swanson,et al.  Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study. , 1983, Neuroendocrinology.

[189]  K. Fuxe,et al.  Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain , 1974 .

[190]  M. Sauvage,et al.  Detection of corticotropin-releasing hormone receptor 1 immunoreactivity in cholinergic, dopaminergic and noradrenergic neurons of the murine basal forebrain and brainstem nuclei – potential implication for arousal and attention , 2001, Neuroscience.

[191]  A. Basbaum,et al.  Colocalization of immunoreactive proenkephalin and prodynorphin products in medullary neurons of the rat , 1984, Neuropeptides.

[192]  M. T. Shipley,et al.  Surprisingly rich projection from locus coeruleus to the olfactory bulb in the rat , 1985, Brain Research.

[193]  S. Watson,et al.  Interaction of opiate peptide and noradrenalin systems: Light microscopic studies , 1980, Peptides.

[194]  C. Saper,et al.  Opioid peptide immunoreactivity in spinal and trigeminal dorsal horn neurons projecting to the parabrachial nucleus in the rat , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[195]  S. Foote,et al.  Efferent projections of nucleus locus coeruleus: Morphologic subpopulations have different efferent targets , 1986, Neuroscience.

[196]  E. V. Van Bockstaele,et al.  Efferent projections of the nucleus of the solitary tract to peri‐locus coeruleus dendrites in rat brain: Evidence for a monosynaptic pathway , 1999, The Journal of comparative neurology.

[197]  J. Gugten,et al.  Vasopressin and noradrenaline coexistence in the rat locus ceruleus: differential decreases of their levels in distant brain areas after thermal and neurotoxic lesions , 1988, Brain Research.

[198]  Shelagh Wilson,et al.  Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord☆ , 1999, Peptides.

[199]  N. Ling,et al.  Differential distribution of urocortin- and corticotropin-releasing factor-like immunoreactivities in the rat brain , 1999, Neuroscience.

[200]  P. Cuatrecasas,et al.  Immunohistochemical localization of enkephalin in rat brain and spinal cord , 1978, The Journal of comparative neurology.

[201]  E. Stone,et al.  Further evidence for a glial localization of rat cortical β-adrenoceptors: studies of in vivo cyclic AMP responses to catecholamines , 1991, Brain Research.

[202]  T. Hökfelt,et al.  Distribution of substance P-like immunoreactivity in the central nervous system of the rat—I. Cell bodies and nerve terminals , 1978, Neuroscience.

[203]  M. Tohyama,et al.  Cellular organization of locus coeruleus in the rat as studied by Golgi method. , 1978, Archivum histologicum Japonicum = Nihon soshikigaku kiroku.

[204]  M. Bennett,et al.  Comparative study on the distribution patterns of P2X1–P2X6 receptor immunoreactivity in the brainstem of the rat and the common marmoset (Callithrix jacchus): Association with catecholamine cell groups , 2000, The Journal of comparative neurology.

[205]  P. J. Larsen,et al.  Leptin Receptor Immunoreactivity Is Present in Ascending Serotonergic and Catecholaminergic Neurons of the Rat , 2001, Neuroendocrinology.

[206]  G Chouvet,et al.  Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology. , 1991, Progress in brain research.

[207]  D. Lima,et al.  The ventrolateral medulla of the rat is connected with the spinal cord dorsal horn by an indirect descending pathway relayed in the A5 noradrenergic cell group , 1996, The Journal of comparative neurology.

[208]  G. Housley,et al.  Distribution of the P2X2 receptor subunit of the ATP‐gated ion channels in the rat central nervous system , 1999, The Journal of comparative neurology.

[209]  R. Buijs,et al.  Light and electron microscopic immunocytochemical analysis of the noradrenaline innervation of the rat visual cortex , 1989, Journal of neurocytology.

[210]  P. Guyenet,et al.  Projections of nucleus paragigantocellularis lateralis to locus coeruleus and other structures in rat , 1987, Brain Research.

[211]  M. Kuhar,et al.  Autoradiographic localization of opiate receptors in rat brain. II. The brain stem , 1977, Brain Research.

[212]  E. V. Van Bockstaele,et al.  Evidence for coexistence of enkephalin and glutamate in axon terminals and cellular sites for functional interactions of their receptors in the rat locus coeruleus , 2000, The Journal of comparative neurology.

[213]  B. Jones,et al.  Noradrenergic locus coeruleus neurons: their distant connections and their relationship to neighboring (including cholinergic and GABAergic) neurons of the central gray and reticular formation. , 1991, Progress in brain research.

[214]  E. V. Bockstaele,et al.  Ultrastructural localization of the kainate selective glutamate receptor in noradrenergic perikarya and dendrites of the nucleus locus coeruleus in the rat brain , 1996, Brain Research.

[215]  W. Nauta,et al.  Efferent connections of the substantia nigra and ventral tegmental area in the rat , 1979, Brain Research.

[216]  L. Rinaman,et al.  Pseudorabies virus infection of the rat central nervous system: ultrastructural characterization of viral replication, transport, and pathogenesis , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[217]  R. North,et al.  Characterization of α2-adrenoceptors which increase potassium conductance in rat locus coeruleus neurones , 1985, Neuroscience.

[218]  P. Petrusz,et al.  The immunocytochemical localization of enkephalin in the central nervous system of the rat , 1981, The Journal of comparative neurology.

[219]  T. Gray,et al.  Catecholamine and NPY efferents from the ventrolateral medulla to the amygdala in the rat , 1995, Brain Research Bulletin.

[220]  G. Leanza,et al.  Branching projections from subcoeruleus area neurons to medial preoptic area and cervical spinal cord revealed by double retrograde neuronal labeling , 1989, Neuroscience Letters.

[221]  F. Bloom,et al.  A rapid, simple and sensitive method for the demonstration of central catecholamine-containing neurons and axons by glyoxylic acid-induced fluorescence. II. A detailed description of methodology. , 1976, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[222]  Cedric L. Williams,et al.  Adrenergic activation of the nucleus tractus solitarius potentiates amygdala norepinephrine release and enhances retention performance in emotionally arousing and spatial memory tasks , 2000, Behavioural Brain Research.

[223]  Clifford B. Saper,et al.  Reciprocal parabrachial-cortical connections in the rat , 1982, Brain Research.

[224]  J. Korf,et al.  Bilaterally diverging axon collaterals and contralateral projections from rat locus coeruleus neurons, demonstrated by fluorescent retrograde double labeling and norepinephrine metabolism , 2005, Journal of Neural Transmission.

[225]  J. D. McGaugh Memory--a century of consolidation. , 2000, Science.

[226]  F. Gallyas,et al.  High-grade intensification of the end-product of the diaminobenzidine reaction for peroxidase histochemistry. , 1982, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[227]  M. Palkovits,et al.  Distribution of vasoactive intestinal polypeptide (VIP) in the rat brain stem nuclei , 1982, Brain Research.

[228]  E. V. Bockstaele,et al.  Light and electron microscopic evidence for topographic and monosynaptic projections from neurons in the ventral medulla to noradrenergic dendrites in the rat locus coeruleus , 1998, Brain Research.

[229]  N. Shimizu,et al.  The fine structural organization of the locus coeruleus in the rat with reference to noradrenaline contents , 1979, Experimental Brain Research.

[230]  E. V. Van Bockstaele,et al.  Periaqueductal gray neurons monosynaptically innervate extranuclear noradrenergic dendrites in the rat pericoerulear region , 2000, The Journal of comparative neurology.

[231]  D. Reis,et al.  Electron microscopic localization of substance P and enkephalin in axon terminals related to dendrites of catecholaminergic neurons , 1979, Brain Research.

[232]  G. Aston-Jones,et al.  Discharge of noradrenergic locus coeruleus neurons in behaving rats and monkeys suggests a role in vigilance. , 1991, Progress in brain research.

[233]  James N. Davis,et al.  Anatomy of brain alpha1‐adrenergic receptors: In vitro autoradiography with [125I]‐heat , 1985, The Journal of comparative neurology.

[234]  M. I. Smith,et al.  Orexin A activates locus coeruleus cell firing and increases arousal in the rat. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[235]  P. Sawchenko,et al.  Organization of galanin‐immunoreactive inputs to the paraventricular nucleus with special reference to their relationship to catecholaminergic afferents , 1987, The Journal of comparative neurology.

[236]  J. Williams,et al.  Forskolin enhancement of opioid currents in rat locus coeruleus neurons. , 1996, Journal of neurophysiology.

[237]  J. Willoughby,et al.  Distribution of tyrosine hydroxylase and neuropeptide Y–like immunoreactive neurons in rabbit medulla oblongata, with attention to colocalization studies, presumptive adrenaline‐synthesizing perikarya, and vagal preganglionic cells , 1986, The Journal of comparative neurology.

[238]  W. Cowan,et al.  The efferent connections of the ventromedial nucleus of the hypothalamus of the rat , , 1976, The Journal of comparative neurology.

[239]  A. Beitz The sites of origin brain stem neurotensin and serotonin projections to the rodent nucleus raphe magnus , 1982, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[240]  G. Aston-Jones,et al.  Projections from the periaqueductal gray to the rostromedial pericoerulear region and nucleus locus coeruleus: Anatomic and physiologic studies , 1991, The Journal of comparative neurology.

[241]  G. Aston-Jones,et al.  Role of the locus coeruleus in emotional activation. , 1996, Progress in brain research.

[242]  P. Coleman,et al.  Neuron numbers in locus coeruleus do not change with age in fisher 344 rat , 1981, Neurobiology of Aging.

[243]  G. Leanza,et al.  Branching axons from subcoeruleus area project to the nucleus raphe pontis and hypothalamic zona incerta, as studied with the double fluorescent retrograde tracing technique , 1988, Neuroscience Letters.

[244]  J. Brown,et al.  Central somatostatin systems revealed with monoclonal antibodies , 1985, The Journal of comparative neurology.

[245]  M. Geffard,et al.  Coexistence of vasopressin, neurophysin and noradrenaline immunoreactivity in medium-sized cells of the locus coeruleus and subcoeruleus in the rat , 1985, Brain Research.

[246]  K. Kitahama,et al.  Biochemical evidence for an interaction between adrenaline and noradrenaline neurons in the rat brainstem , 1986, Brain Research.

[247]  P. Luppi,et al.  Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep , 1998, The European journal of neuroscience.

[248]  G. Aghajanian,et al.  Catecholamine receptors on locus coeruleus neurons: pharmacological characterization. , 1977, European journal of pharmacology.

[249]  James H. Fallon,et al.  Locus coeruleus projections to cortex: Topography, morphology and collateralization , 1982, Brain Research Bulletin.

[250]  L. Záborszky,et al.  Direct catecholaminergic‐cholinergic interactions in the basal forebrain. I. Dopamine‐β‐hydroxylase‐ and tyrosine hydroxylase input to cholinergic neurons , 1996, The Journal of comparative neurology.

[251]  G. Aston-Jones,et al.  Preoptic projections to Barringon's nucleus and the pericoerulear region: Architecture and terminal organization , 1994, The Journal of comparative neurology.

[252]  J. Cohen,et al.  The role of locus coeruleus in the regulation of cognitive performance. , 1999, Science.

[253]  Howard T. Chang Noradrenergic innervation of the substantia innominata: A light and electron microscopic analysis of dopamine β-hydroxylase immunoreactive elements in the rat , 1989, Experimental Neurology.

[254]  L. Olson,et al.  A new major projection from locus coeruleus: The main source of noradrenergic nerve terminals in the ventral and dorsal columns of the spinal cord , 1977, Brain Research.

[255]  Floyd E. Bloom,et al.  Ultrastructural identification of noradrenergic terminals in rat hippocampus: unilateral destruction of the locus coeruleus with 6-hydroxydopamine , 1978, Brain Research.

[256]  D. Reis,et al.  Adrenergic neurons in the rostral ventrolateral medulla: ultrastructure and synaptic relations with other transmitter-identified neurons. , 1989, Progress in brain research.

[257]  G. Aston-Jones,et al.  Inhibition of noradrenergic locus coeruleus neurons by C1 adrenergic cells in the rostral ventral medulla , 1992, Neuroscience.

[258]  K. Iijima,et al.  Immunocytochemical study using a GABA antiserum for the demonstration of inhibitory neurons in the rat locus ceruleus. , 1988, The American journal of anatomy.

[259]  W. Foote,et al.  The efferent connection of the nucleus raphe dorsalis , 1976, Brain Research.

[260]  Floyd E. Bloom,et al.  Anatomy and physiology of locus coeruleus neurons: functional implications , 1984 .

[261]  G. Aston-Jones,et al.  Origin of noradrenergic afferents to the shell subregion of the nucleus accumbens: anterograde and retrograde tract-tracing studies in the rat , 1998, Brain Research.

[262]  M. Jouvet,et al.  Evidence for the presence of enkephalin in catecholaminergic neurones of cat locus coeruleus , 1982, Neuroscience Letters.

[263]  D. Jacobowitz,et al.  Selective action of 6-hydroxydopa on noradrenergic terminals: mapping of preterminal axons of the brain. , 1971, Life sciences. Pt. 1: Physiology and pharmacology.

[264]  M. Sakanaka,et al.  Corticotropin releasing factor‐like immunoreactivity in the rat brain as revealed by a modified cobalt‐glucose oxidase‐diaminobenzidine method , 1987, The Journal of comparative neurology.

[265]  D. Jacobowitz,et al.  Immunohistochemical mapping of galanin-like neurons in the rat central nervous system , 1985, Peptides.

[266]  L. Descarries,et al.  Disappearance of the locus coeruleus in the rat after intraventricular 6-hydroxdopamine. , 1972, Brain research.

[267]  W. T. Nickell,et al.  The brain nucleus locus coeruleus: restricted afferent control of a broad efferent network. , 1986, Science.

[268]  G. Aston-Jones,et al.  Potent inhibitory input to locus coeruleus from the nucleus prepositus hypoglossi , 1989, Brain Research Bulletin.

[269]  D. Reis,et al.  Anatomical substrates of cholinergic‐autonomic regulation in the rat , 1990, The Journal of comparative neurology.

[270]  C. Aoki Beta-adrenergic receptors: astrocytic localization in the adult visual cortex and their relation to catecholamine axon terminals as revealed by electron microscopic immunocytochemistry , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[271]  C. Leonard,et al.  Connections of the median and dorsal raphe nuclei in the rat: An autoradiographic and degeneration study , 1974, The Journal of comparative neurology.

[272]  T. Hökfelt,et al.  Immunohistochemical distribution of somatostatin-like immunoreactivity in the central nervous system of the adult rat , 1984, Neuroscience.

[273]  H. Proudfit,et al.  Bidirectional modulation of nociception by GABA neurons in the dorsolateral pontine tegmentum that tonically inhibit spinally projecting noradrenergic A7 neurons , 2000, Neuroscience.

[274]  Gary Aston-Jones,et al.  Brain aminergic axons exhibit marked variability in conduction velocity , 1980, Brain Research.

[275]  G. Aston-Jones,et al.  Hypocretin/orexin depolarizes and decreases potassium conductance in locus coeruleus neurons , 2000, Neuroreport.

[276]  H. Proudfit,et al.  Ultrastructural evidence that substance P neurons form synapses with noradrenergic neurons in the A7 catecholamine cell group that modulate nociception , 1999, Neuroscience.

[277]  E. V. Van Bockstaele,et al.  Mu‐opioid receptor is located on the plasma membrane of dendrites that receive asymmetric synapses from axon terminals containing leucine‐enkephalin in the rat nucleus locus coeruleus , 1996, The Journal of comparative neurology.

[278]  G. Aston-Jones,et al.  Potent excitatory influence of prefrontal cortex activity on noradrenergic locus coeruleus neurons , 1998, Neuroscience.

[279]  W. T. Nickell,et al.  Chemoanatomical organization of the noradrenergic input from locus coeruleus to the olfactory bulb of the adult rat , 1989, The Journal of comparative neurology.

[280]  T. Hökfelt,et al.  Locus coeruleus neurons in the rat containing neuropeptide Y, tyrosine hydroxylase or galanin and their efferent projections to the spinal cord, cerebral cortex and hypothalamus , 1988, Neuroscience.

[281]  E. V. Van Bockstaele,et al.  Corticotropin‐releasing factor‐containing axon terminals synapse onto catecholamine dendrites and may presynaptically modulate other afferents in the rostral pole of the nucleus locus coeruleus in the rat brain , 1996, The Journal of comparative neurology.

[282]  E. V. Bockstaele,et al.  α 2A-adrenergic receptors in the rat nucleus locus coeruleus: subcellular localization in catecholaminergic dendrites, astrocytes, and presynaptic axon terminals , 1998, Brain Research.

[283]  G. Uhl,et al.  Iontophoresis of neurotensin in the area of the locus coeruleus , 1978, Brain Research.

[284]  P. Guyenet,et al.  A5 noradrenergic neurons and the carotid sympathetic chemoreflex. , 1994, The American journal of physiology.

[285]  R. M. Bowker,et al.  Origins of spinal noradrenergic pathways demonstrated by retrograde transport of antibody to dopamine-β-hydroxylase , 1981, Neuroscience Letters.

[286]  T. Gray,et al.  Organization of peptidergic and catecholaminergic efferents from the nucleus of the solitary tract to the rat amygdala , 1990, Brain Research Bulletin.

[287]  H. Okamura,et al.  Immunocytochemical distribution of met‐enkephalin‐Arg6‐Gly7‐Leu8 in the rat lower brainstem , 1987, The Journal of comparative neurology.

[288]  J. Fritschy,et al.  Demonstration of two separate descending noradrenergic pathways to the rat spinal cord: Evidence for an intragriseal trajectory of locus coeruleus axons in the superficial layers of the dorsal horn , 1990, The Journal of comparative neurology.

[289]  R. Valentino Corticotropin-releasing factor: putative neurotransmitter in the noradrenergic nucleus locus ceruleus. , 1989, Psychopharmacology bulletin.

[290]  F. M. Clark,et al.  The projection of locus coeruleus neurons to the spinal cord in the rat determined by anterograde tracing combined with immunocytochemistry , 1991, Brain Research.

[291]  R. Blakely,et al.  Biogenic amine transporters: regulation in flux , 2000, Current Opinion in Neurobiology.

[292]  Menek Goldstein,et al.  Activation of the locus coeruleus induced by selective stimulation of the ventral tegmental area , 1986, Brain Research.

[293]  G. Aston-Jones,et al.  Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion , 2000, Nature.

[294]  Jun Lu,et al.  Afferents to the Ventrolateral Preoptic Nucleus , 2002, The Journal of Neuroscience.

[295]  L. Swanson The locus coeruleus: A cytoarchitectonic, golgi and immunohistochemical study in the albino rat , 1976, Brain Research.

[296]  H. Milon,et al.  Serotonin and dopamine afferents to the rat locus coeruleus: a biochemical study after lesioning of the ventral mesencephalic tegmental-A10 region and the raphe´dorsalis , 1983, Brain Research.

[297]  James N. Davis,et al.  Differential distribution of locus coeruleus projections to the hippocampal formation: anatomical and biochemical evidence , 1985, Brain Research.

[298]  M. E. Lewis,et al.  Enkephalin systems in diencephalon and brainstem of the rat , 1983, The Journal of comparative neurology.