Microbiosensor based on magnetostrictive microcantilever

Biosensors for detecting and quantifying the presence of a small amount of biological threat agents in a real-time manner are urgently needed for a wide range of applications. In this paper, a novel type of micro-biosensor platform - magnetostrictive microcantilever (MMC) - is reported. The resonance behavior and the sensitivity of MMC are characterized and compared to the theoretical calculation. Additionally, the quality merit factor (Q value) was characterized. It is found: 1) the MMC exhibits a sensitivity of about 50% higher than that of piezoelectric-based microcantilevers and 2) the MMC has a high Q value (~140 in air and 50 in yeast suspension). A biosensor for detecting yeast cells in water is built based on MMC. The performance of the biosensor is characterized.

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