Biocatalytic membrane reactors: applications and perspectives.

Membranes and biotechnological tools can be used for improving traditional production systems to maintain the sustainable growth of society. Typical examples include: new and improved foodstuffs, in which the desired nutrients are not lost during thermal treatment; novel pharmaceutical products with well-defined enantiomeric compositions; and the treatment of waste-water, wherein pollution by traditional processes is a problem.

[1]  F. Malcata,et al.  Hydrolysis of butteroil by immobilized lipase using a hollow‐fiber reactor: Part II. Uniresponse kinetic studies , 1992, Biotechnology and bioengineering.

[2]  F. Alfani,et al.  Study of Michaelis-Menten kinetics with linear-type product inhibition in ultrafiltration membrane reactors: Mathematical model, experimental and data , 1990 .

[3]  M. McGrath,et al.  Membrane Bioreactor for Control of Volatile Organic Compound Emissions , 1997 .

[4]  Kazuo Yamamoto,et al.  Biological Nitrogen Removal under Low Temperature in a Membrane Separation Bioreactor , 1993 .

[5]  W. Chick,et al.  Beta cell culture on synthetic capillaries: an artificial endocrine pancreas , 1975, Science.

[6]  J. Rhee,et al.  Continuous hydrolysis of olive oil by immobilized lipase in organic solvent. , 1992, Biotechnology and bioengineering.

[7]  J. Timmer,et al.  Efficiency of lactic acid production by Lactobacillus helveticus in a membrane cell recycle reactor , 1994 .

[8]  Alan S. Michaels Frontiers of Bioseparations Technology: Unsolved Problems and Novel Process Concepts , 1990 .

[9]  Alexander M. Klibanov,et al.  Enzyme-catalyzed processes in organic solvents. , 1985 .

[10]  E. Drioli,et al.  Hydrolysis and regioselective transesterification catalyzed by immobilized lipases in membrane bioreactors , 1997 .

[11]  E. Drioli,et al.  Study of Fouling Phenomena in Apple Juice Clarification by Enzyme Membrane Reactor , 1998 .

[12]  M. Jaffrin,et al.  Permeate flux enhancement by pressure and flow pulsations in microfiltration with mineral membranes , 1992 .

[13]  J. Winter Environmental Processes I, wastewater treatment. , 1999 .

[14]  M. Rikimaru,et al.  Hybrid bioartificial liver in hepatic failure: preliminary clinical report. , 1987, Surgery.

[15]  D. Bianchi,et al.  Performance of a biphasic organic/aqueous hollow fibre reactor using immobilized lipase , 1995 .

[16]  T. Tosa,et al.  Immobilized Aspartase-Containing Microbial Cells: Preparation and Enzymatic Properties , 1974, Applied microbiology.

[17]  A. Bader,et al.  A Novel Full‐Scale Flat Membrane Bioreactor Utilizing Porcine Hepatocytes: Cell Viability and Tissue‐Specific Functions , 2000, Biotechnology progress.

[18]  K Brindle,et al.  The application of membrane biological reactors for the treatment of wastewaters. , 2000, Biotechnology and bioengineering.

[19]  M. W. Reij,et al.  Membrane bioreactors for waste gas treatment. , 1998 .

[20]  F. Morisi,et al.  [57] Lactose reduction of milk by fiber-entrapped β-galactosidase. Pilot-plant experiments , 1976 .

[21]  Kazuo Yamamoto,et al.  Direct Solid-Liquid Separation Using Hollow Fiber Membrane in an Activated Sludge Aeration Tank , 1989 .

[22]  P. J. Wan,et al.  Introduction to fats and oils technology. , 1991 .

[23]  T. Tosa Industrial application of immobilized biocatalysts , 1991 .

[24]  PERFORMANCE OF ROTARY DISK MODULES IN A COLLECTED HUMAN EXCRETA TREATMENT PLANT , 1994 .

[25]  L. J. Andrés,et al.  Microfiltration of apple juice using inorganic membranes : Process optimization and juice stability , 1996 .

[26]  David F. Ollis,et al.  Biochemical Engineering Fundamentals , 1976 .

[27]  J. Vacanti,et al.  Tissue engineering : Frontiers in biotechnology , 1993 .

[28]  E. Drioli,et al.  Biocatalytic Membrane Reactors , 1998 .

[29]  Masayuki Fukagawa,et al.  Fermentation Wastewater Treatment in a Membrane Bioreactor , 1999 .

[30]  E. Drioli,et al.  Theoretical and experimental analysis of a hybrid bioartificial membrane pancreas: a distributed parameter model taking into account starling fluxes , 1990 .

[31]  S. Bouhallab,et al.  Continuous hydrolysis of caseinomacropeptide in a membrane reactor: kinetic study and gram-scale production of antithrombotic peptides , 1995 .

[32]  F. Malcata,et al.  Use of a lipase immobilized in a membrane reactor to hydrolyze the glycerides of butteroil , 1991, Biotechnology and bioengineering.

[33]  M. Goto,et al.  Hydrolysis of triolein by lipase in a hollow fiber reactor , 1992 .

[34]  G. Trägårdh Membrane Applications in the Food Industry , 1991 .

[35]  G. Giovanelli,et al.  Beverage stabilization through enzymatic removal of phenolics , 1989 .

[36]  N. Sakamoto Effect of enzyme concentration on the dynamic behavior of a membrane-bound enzyme system , 1992 .

[37]  F. Wang,et al.  Lipolytic activities of a lipase immobilized on six selected supporting materials , 1990, Biotechnology and bioengineering.

[38]  Hydrolysis of soybean oil by lipase with a bioreactor having two different membranes , 1993 .

[39]  Y. Nemerson,et al.  A microscopic model of enzyme kinetics. , 1995, Biophysical journal.

[40]  F. Malcata,et al.  Hydrolysis of butteroil by immobilized lipase using a hollow‐fiber reactor: Part I. Lipase adsorption studies , 1992, Biotechnology and bioengineering.

[41]  C. Horváth,et al.  External and internal diffusion in heterogeneous enzymes systems , 1974, Biotechnology and bioengineering.

[42]  K. Nishimura,et al.  Biological Denitrification System with Membrane Separation for Collective Human Excreta Treatment Plant , 1992 .

[43]  M. Ikemi,et al.  Sorbitol production in charged membrane bioreactor with coenzyme regeneration system: I. Selective retainment of NADP(H) in a continuous reaction , 1990, Biotechnology and bioengineering.

[44]  A. Illanes,et al.  Immobilization of lactase for the continuous hydrolysis of whey permaete , 1990 .

[45]  G. Carta,et al.  Synthesis of lovastatin with immobilized Candida rugosa lipase in organic solvents: Effects of reaction conditions on initial rates. , 1997, Biotechnology and bioengineering.

[46]  M. W. Reij,et al.  Membrane bioreactor with a porous hydrophobic membrane as a gas–liquid contactor for waste gas treatment , 1995, Biotechnology and bioengineering.

[47]  Y. Nonaka,et al.  On the mechanism of the action of thermolysin: kinetic study of the thermolysin-catalysed condensation reaction of N-benzyloxycarbonyl-L-aspartic acid with L-phenylalanine methyl ester , 1981 .

[48]  T. Tosa,et al.  Optical resolution of racemic amino acids by aminoacylase. , 1993, Bioprocess technology.

[49]  T. Bucciarelli,et al.  A New Polymethylmethacrylate Membrane for Hemodialysis , 1996, The International journal of artificial organs.

[50]  M. Fick,et al.  Membrane bioreactor for lactic acid production , 1996 .

[51]  M. Stenstrom,et al.  Treatment of Hydrolysates of the High Explosives Hexahydro‐1,3,5,‐Trinitro‐1,3,5‐Trianize and Octahydro‐1,3,5,7‐Tetranitro‐1,3,5,7‐Tetrazocine Using Biological Denitrification , 1999 .

[52]  P. Kerkhof,et al.  The hydrolysis of triglycerides by immobilized lipase in a hydrophiiic membrane reactor , 1988, Biotechnology and bioengineering.

[53]  Stephen L. Matson,et al.  A multiphase/extractive enzyme membrane reactor for production of diltiazem chiral intermediate , 1997 .

[54]  W D Payne,et al.  Hepatocyte culture systems for artificial liver support: Implications for critical care medicine (bioartificial liver support) , 1992, Critical care medicine.

[55]  A. Klibanov Asymmetric transformations catalyzed by enzymes in organic solvents , 1990 .

[56]  J. Gerlach,et al.  Use of Hepatocytes in Adhesion and Suspension Cultures for Liver Support Bioreactors , 1989, The International journal of artificial organs.

[57]  D. Bianchi,et al.  Enzymatic resolution of (S)‐(+)‐naproxen in a continuous reactor , 1991, Biotechnology and bioengineering.