Potential Complications of Percutaneous Vertebroplasty Combined with Interstitial Implantation of 125I Seeds for Metastatic Spinal Tumors: A Case Report and Literary Review

Percutaneous vertebroplasty is often used to acquire the stability of the spine and relieve the pain caused by osteoporotic vertebral compressive fracture (OVCF). 125I seeds have been used for application of local therapy for tumors. A combined treatment was reported in previous literatures. Thus, this case report is aimed at reporting a patient with an occurrence of delayed radioactive myelopathy, who accepted percutaneous vertebroplasty combined with interstitial implantation of 125I seeds for metastatic spinal tumors, and at reviewing the published literatures.

[1]  Yuehua Wu,et al.  Which Combination Treatment Is Better for Spinal Metastasis: Percutaneous Vertebroplasty With Radiofrequency Ablation, 125I Seed, Zoledronic Acid, or Radiotherapy? , 2017, American journal of therapeutics.

[2]  A. Karathanasi,et al.  Metastatic Spinal Cord Compression: Unraveling the Diagnostic and Therapeutic Challenges , 2018, AntiCancer Research.

[3]  I. Izbudak,et al.  Radiation-Induced Myelitis: Initial and Follow-Up MRI and Clinical Features in Patients at a Single Tertiary Care Institution during 20 Years , 2018, American Journal of Neuroradiology.

[4]  Joseph S. Cheng,et al.  Thirty-day complication and readmission rates associated with resection of metastatic spinal tumors: a single institutional experience. , 2018, Journal of spine surgery.

[5]  Shi Gao,et al.  DTI and pathological changes in a rabbit model of radiation injury to the spinal cord after 125I radioactive seed implantation , 2018, Neural regeneration research.

[6]  M. Keřkovský,et al.  Diffusion Tensor Imaging in Radiation‐Induced Myelopathy , 2015, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

[7]  Shixin Wang,et al.  Clinical curative effect of percutaneous vertebroplasty combined with 125I-seed implantation in treating spinal metastatic tumor. , 2015, Pakistan journal of pharmaceutical sciences.

[8]  Mingyan Ren,et al.  Status and prospects of percutaneous vertebroplasty combined with 125I seed implantation for the treatment of spinal metastases , 2015, World Journal of Surgical Oncology.

[9]  B. Liu,et al.  A preliminary comparative clinical study of vertebroplasty with multineedle or single-needle interstitial implantation of (125)I seeds in the treatment of osteolytic metastatic vertebral tumors. , 2014, Journal of neurosurgery. Spine.

[10]  Shaonian Xu,et al.  [Treatment of metastatic thoracolumbar tumors by percutaneous vertebroplasty combined with interstitial implantation of ¹²⁵I seeds]. , 2014, Zhonghua zhong liu za zhi [Chinese journal of oncology].

[11]  Zuozhang Yang,et al.  Percutaneous vertebroplasty combined with interstitial implantation of 125I seeds in banna mini-pigs , 2013, World Journal of Surgical Oncology.

[12]  Jinlei Zhang,et al.  Clinical investigations on the spinal osteoblastic metastasis treated by combination of percutaneous vertebroplasty and (125)I seeds implantation versus radiotherapy. , 2013, Cancer biotherapy & radiopharmaceuticals.

[13]  M. Çekinmez,et al.  Delayed radiation myelopathy: Differential diagnosis with positron emission tomography/computed tomography examination , 2012, Asian journal of neurosurgery.

[14]  Jinlei Zhang,et al.  Pathological impairments induced by interstitial implantation of 125I Seeds in spinal canal of banna mini-pigs , 2012, World Journal of Surgical Oncology.

[15]  Y. Tao,et al.  A patient with lung cancer metastatic to the fifth thoracic vertebra and spinal cord compression treated with percutaneous vertebroplasty and I-125 seed implantation. , 2011, Diagnostic and Interventional Radiology.

[16]  B. Georgy.  Vertebroplasty technique in metastatic disease. , 2010, Neuroimaging clinics of North America.

[17]  Zuozhang Yang,et al.  Treatment of metastatic spinal tumors by percutaneous vertebroplasty versus percutaneous vertebroplasty combined with interstitial implantation of 125I seeds , 2009, Acta radiologica.

[18]  Gamal Baroud,et al.  High-Viscosity Cement Significantly Enhances Uniformity of Cement Filling in Vertebroplasty: An Experimental Model and Study on Cement Leakage , 2006, Spine.

[19]  K. Ahrar,et al.  Percutaneous vertebroplasty and kyphoplasty for painful vertebral body fractures in cancer patients , 2003 .

[20]  D F Kallmes,et al.  Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. , 1997, AJNR. American journal of neuroradiology.