Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.
暂无分享,去创建一个
Shaun S. Sanders | M. Hayden | A. El-Husseini | Junmei Wan | R. Singaraja | Jeffrey B Carroll | Michael R Hayden | J. Carroll | Roshni Singaraja | Rujun Kang | Alaa El-Husseini | Kun Huang | Kun Huang | Junmei Wan | Liza M. Sutton | Shaun S Sanders | Fiona B Young | Nicholas G Davis | Liza Sutton | Lili Liu | F. Young | Rujun Kang | N. Davis | Lili Liu
[1] Michael S. Levine,et al. Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice , 2000, Nature Genetics.
[2] M. MacDonald,et al. Huntingtin: Alive and Well and Working in Middle Management , 2003, Science's STKE.
[3] M. Resh. Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. , 1999, Biochimica et biophysica acta.
[4] Virginia E. Papaioannou,et al. Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue , 1995, Nature Genetics.
[5] R. Deschenes,et al. DHHC9 and GCP16 Constitute a Human Protein Fatty Acyltransferase with Specificity for H- and N-Ras* , 2005, Journal of Biological Chemistry.
[6] P. Reddy,et al. Polyglutamine-expanded Huntingtin Promotes Sensitization of N-Methyl-d-aspartate Receptors via Post-synaptic Density 95* , 2001, The Journal of Biological Chemistry.
[7] M. Hayden,et al. Wild‐type huntingtin protects neurons from excitotoxicity , 2006, Journal of neurochemistry.
[8] S. W. Davies,et al. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. , 1997, Science.
[9] L. Raymond,et al. Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin , 2006, Cell.
[10] R. Deschenes,et al. Identification of a Ras Palmitoyltransferase in Saccharomyces cerevisiae * , 2002, The Journal of Biological Chemistry.
[11] S. Hersch,et al. HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis. , 2002, Human molecular genetics.
[12] J. Olson,et al. Expression Profiling of Huntington's Disease Models Suggests That Brain-Derived Neurotrophic Factor Depletion Plays a Major Role in Striatal Degeneration , 2007, The Journal of Neuroscience.
[13] John R. Yates,et al. Neural Palmitoyl-Proteomics Reveals Dynamic Synaptic Palmitoylation , 2008, Nature.
[14] J. Olson,et al. Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration , 2007, PLoS genetics.
[15] J. Hodgson,et al. Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo. , 2001, American journal of human genetics.
[16] Harry T Orr,et al. Trinucleotide repeat disorders. , 2007, Annual review of neuroscience.
[17] S. Humbert,et al. Huntington’s disease: from huntingtin function and dysfunction to therapeutic strategies , 2006, Cellular and Molecular Life Sciences CMLS.
[18] R. Carraway,et al. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons , 1995, Neuron.
[19] F. Perez,et al. Identification of G Protein α Subunit-Palmitoylating Enzyme , 2008, Molecular and Cellular Biology.
[20] J. Caviston,et al. Huntingtin facilitates dynein/dynactin-mediated vesicle transport , 2007, Proceedings of the National Academy of Sciences.
[21] Shaun S. Sanders,et al. Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease , 2010, Neurobiology of Disease.
[22] A. Kihara,et al. Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. , 2006, Biochimica et biophysica acta.
[23] Elena Cattaneo,et al. Normal huntingtin function: an alternative approach to Huntington's disease , 2005, Nature Reviews Neuroscience.
[24] J. Yates,et al. Global Analysis of Protein Palmitoylation in Yeast , 2006, Cell.
[25] L. Raymond,et al. Cleavage at the 586 Amino Acid Caspase-6 Site in Mutant huntingtin Influences Caspase-6 Activation In Vivo , 2010, The Journal of Neuroscience.
[26] P. Brundin,et al. Synaptic dysfunction in Huntington’s disease: a new perspective , 2005, Cellular and Molecular Life Sciences CMLS.
[27] D. Borchelt,et al. Characterization of Huntingtin Pathologic Fragments in Human Huntington Disease, Transgenic Mice, and Cell Models , 2007, Journal of neuropathology and experimental neurology.
[28] D. Rubinsztein,et al. Huntington's disease: from pathology and genetics to potential therapies. , 2008, The Biochemical journal.
[29] Manish S. Shah,et al. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes , 1993, Cell.
[30] Shaun S. Sanders,et al. Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[31] Lu Gan,et al. Palmitoylation of huntingtin by HIP14is essential for its trafficking and function , 2006, Nature Neuroscience.
[32] Blair R. Leavitt,et al. Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease , 2001, Science.
[33] Wei Li,et al. Expression and Characterization of Full-length Human Huntingtin, an Elongated HEAT Repeat Protein* , 2006, Journal of Biological Chemistry.
[34] S. Finkbeiner,et al. Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease* , 2010, The Journal of Biological Chemistry.
[35] D. Bredt,et al. Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase , 2006, The Journal of cell biology.
[36] A. Willems,et al. Studies on the transformation of intact yeast cells by the LiAc/SS‐DNA/PEG procedure , 1995, Yeast.
[37] A. Hackam,et al. Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi , 2002, Nature Cell Biology.
[38] Linyi Chen,et al. The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase , 2002, The Journal of cell biology.
[39] J. Caviston,et al. Huntingtin as an essential integrator of intracellular vesicular trafficking. , 2009, Trends in cell biology.
[40] J. Gorski,et al. Early Striatal Dendrite Deficits followed by Neuron Loss with Advanced Age in the Absence of Anterograde Cortical Brain-Derived Neurotrophic Factor , 2004, The Journal of Neuroscience.
[41] K. Montin,et al. 6-Phosphogluconate Dehydrogenase Mechanism , 2010, The Journal of Biological Chemistry.
[42] A. El-Husseini,et al. Modulation of neuronal protein trafficking and function by palmitoylation , 2005, Current Opinion in Neurobiology.
[43] S. Hersch,et al. Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[44] W. N. Green,et al. Labeling and quantifying sites of protein palmitoylation. , 2004, BioTechniques.
[45] Fabrice P Cordelières,et al. Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules , 2004, Cell.
[46] Hillel Adesnik,et al. Identification of PSD-95 Palmitoylating Enzymes , 2004, Neuron.
[47] Claire-Anne Gutekunst,et al. Huntingtin-Interacting Protein HIP14 Is a Palmitoyl Transferase Involved in Palmitoylation and Trafficking of Multiple Neuronal Proteins , 2004, Neuron.
[48] A. Joyner,et al. Inactivation of the mouse Huntington's disease gene homolog Hdh. , 1995, Science.
[49] S. Floresco,et al. Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes , 1995, Cell.
[50] Richard G. Brusch,et al. Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila , 2003, Neuron.
[51] Martin Drozda,et al. Depletion of wild‐type huntingtin in mouse models of neurologic diseases , 2003, Journal of neurochemistry.
[52] A. Reiner,et al. Wild-type huntingtin plays a role in brain development and neuronal survival , 2007, Molecular Neurobiology.