The Changes of Surgical Treatment for Symptomatic Uterine Myomas in the Past 15 Years

Study Objective: The aim of this study is to elaborate the changes of the surgical approach of treatment for uterine myomas in Yangpu Hospital in the past 15 years. Design: This was retrospective cohort study. Setting: Yangpu Hospital, Tongji University School of Medicine, Shanghai, China. Materials and Methods: A total of 4113 patients with symptomatic uterine myomas underwent surgical treatments. Interventions: Eight kinds of different surgeries were involved in the study, including abdominal or laparoscopic surgery, hysterectomy, or uterus-sparing myomectomy. Measurements: The study collected patients' clinical data and reviewed surgical access and approach, complications, and the results of following up. Results: A total of 1559 cases (37.9%) underwent uterus-sparing myomectomy, 3005 cases (73.1%) performed laparoscopic surgeries. The percentage of laparoscopic surgery was significantly higher than homochronous data of laparotomy after 2003 (P < 0.001). The per year total of uterus-reserved surgery was proved to be negatively correlated with patient's age (R2 = 0.930; P < 0.001). The rate of myomas recurrence was significantly lower in the combined myomectomy and uterine artery occlusion group (4%, 34/910) than in the single myomectomy group (10.5%, 44/420) (P < 0.001). Conclusions: Retaining uterus and minimally invasive surgery were the important trends of surgical treatment for symptomatic uterine myomas. Laparoscopic uterus-sparing myomectomy may be an alternative to hysterectomy to manage to appropriate patients with uterine myomas.

[1]  W. Catherino,et al.  Uterine fibroids , 2016, Nature Reviews Disease Primers.

[2]  Aamir T Khan,et al.  Uterine fibroids: current perspectives , 2014, International journal of women's health.

[3]  W. Hehenkamp,et al.  Review of nonsurgical/minimally invasive treatments for uterine fibroids , 2012, Current opinion in obstetrics & gynecology.

[4]  M. Mára,et al.  Uterine Artery Embolization Versus Laparoscopic Uterine Artery Occlusion: The Outcomes of a Prospective, Nonrandomized Clinical Trial , 2012, CardioVascular and Interventional Radiology.

[5]  J. Segars,et al.  The estimated annual cost of uterine leiomyomata in the United States. , 2012, American journal of obstetrics and gynecology.

[6]  L. Mettler,et al.  Laparoscopic myomectomy focusing on the myoma pseudocapsule: technical and outcome reports. , 2012, Human reproduction.

[7]  R. Heaton,et al.  The role of laparoscopic myomectomy in the management of uterine fibroids , 2011, Current opinion in obstetrics & gynecology.

[8]  T. Amer,et al.  Uterine Artery Occlusion for Treatment of Symptomatic Uterine Myomas , 2010, JSLS : Journal of the Society of Laparoendoscopic Surgeons.

[9]  Zhongping Cheng,et al.  Early-stage morphological observations of myoma and myometrium after laparoscopic uterine artery occlusion treatment. , 2009, European journal of obstetrics, gynecology, and reproductive biology.

[10]  J. Donnez,et al.  A series of 3190 laparoscopic hysterectomies for benign disease from 1990 to 2006: evaluation of complications compared with vaginal and abdominal procedures , 2009, BJOG : an international journal of obstetrics and gynaecology.

[11]  J. Erian,et al.  Efficacy of laparoscopic subtotal hysterectomy in the management of menorrhagia: 400 consecutive cases , 2008, BJOG : an international journal of obstetrics and gynaecology.

[12]  Zhongping Cheng,et al.  Laparoscopic uterine artery occlusion combined with myomectomy for uterine myomas. , 2008, Journal of minimally invasive gynecology.

[13]  N. Ragni,et al.  Hysterectomy and women satisfaction: total versus subtotal technique , 2008, Archives of Gynecology and Obstetrics.

[14]  B. V. Van Voorhis,et al.  Role, Epidemiology, and Natural History of Benign Uterine Mass Lesions , 2005, Clinical obstetrics and gynecology.

[15]  T. Jenkins Laparoscopic supracervical hysterectomy. , 2004, American journal of obstetrics and gynecology.

[16]  E. Wallach,et al.  Uterine Myomas: An Overview of Development, Clinical Features, and Management , 2004, Obstetrics and gynecology.

[17]  C. Gluud,et al.  Randomised controlled trial of total compared with subtotal hysterectomy with one‐year follow up results , 2003, BJOG : an international journal of obstetrics and gynaecology.

[18]  E. Vittinghoff,et al.  A Randomized Comparison of Total or Supracervical Hysterectomy: Surgical Complications and Clinical Outcomes , 2003, Obstetrics and gynecology.

[19]  David B Dunson,et al.  High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. , 2003, American journal of obstetrics and gynecology.

[20]  C. Birch,et al.  The management of uterine leiomyomas. , 2003, Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC.

[21]  S. Ayers,et al.  Outcomes after total versus subtotal abdominal hysterectomy. , 2002, The New England journal of medicine.

[22]  C. Yuan,et al.  Laparoscopic bipolar coagulation of uterine vessels to treat symptomatic myomas in women with elevated Ca 125. , 2001, The Journal of the American Association of Gynecologic Laparoscopists.

[23]  A. Lanzone,et al.  Long-term results of laparoscopic myomectomy: recurrence rate in comparison with abdominal myomectomy. , 2001, Human reproduction.

[24]  K. Semm New Methods of Pelviscopy (Gynecologic Laparoscopy) for Myomectomy, Ovariectomy, Tubectomy and Adnectomy , 1979, Endoscopy.

[25]  V. Bonney THE TECHNIQUE AND RESULTS OF MYOMECTOMY. , 1931 .