Visualization of Parathyroid Hyperplasia Using 18F-Fluorocholine PET/MR in a Patient With Secondary Hyperparathyroidism.

Several imaging modalities exist for the detection of parathyroid adenomas in patients with primary hyperparathyroidism. Unlike solitary parathyroid adenoma, parathyroid hyperplasia in patients with secondary hyperparathyroidism hitherto is difficult to assess with any imaging modality. Our case of a young patient with chronic kidney failure illustrates that F-fluorocholine PET/MR might be an imaging tool suitable for the diagnosis and presurgical assessment of parathyroid hyperplasia.

[1]  Naval Bansal,et al.  Primary Hyperparathyroidism With Negative Imaging: A Significant Clinical Problem. , 2017, Annals of surgery.

[2]  A. Zwijnenburg,et al.  F18‐Choline PET/CT: a novel tool to localize parathyroid adenoma? , 2015, Clinical endocrinology.

[3]  N. Freedman,et al.  Localization of Parathyroid Adenoma by 11C-Choline PET/CT: Preliminary Results , 2014, Clinical nuclear medicine.

[4]  J. Talbot,et al.  Is 18F-fluorocholine-positron emission tomography/computerized tomography a new imaging tool for detecting hyperfunctioning parathyroid glands in primary or secondary hyperparathyroidism? , 2014, The Journal of clinical endocrinology and metabolism.

[5]  M. Hočevar,et al.  18F-Fluorocholine PET/CT for localization of hyperfunctioning parathyroid tissue in primary hyperparathyroidism: a pilot study , 2014, European Journal of Nuclear Medicine and Molecular Imaging.

[6]  J. Fettich,et al.  Incidental uptake of 18F-fluorocholine (FCH) in the head or in the neck of patients with prostate cancer , 2014, Radiology and oncology.

[7]  A. Delaloye,et al.  Parathyroid dual tracer subtraction scintigraphy: small regions method for quantitative assessment of parathyroid adenoma uptake , 2014, Annals of Nuclear Medicine.

[8]  F. Triponez,et al.  False-positive result in 18F-fluorocholine PET/CT due to incidental and ectopic parathyroid hyperplasia. , 2014, Clinical nuclear medicine.

[9]  K. Choudhury,et al.  Prevalence of the Polar Vessel Sign in Parathyroid Adenomas on the Arterial Phase of 4D CT , 2014, American Journal of Neuroradiology.

[10]  J. Fettich,et al.  Incidental uptake of 18 F-fluorocholine ( FCH ) in the head or in the neck of patients with prostate cancer , 2014 .

[11]  J. Hoang,et al.  How to perform parathyroid 4D CT: tips and traps for technique and interpretation. , 2014, Radiology.

[12]  M. Picchio,et al.  Incidental finding of parathyroid adenoma with 11C-choline PET/CT. , 2012, Clinical nuclear medicine.

[13]  Andrew Kettle,et al.  2009 EANM parathyroid guidelines , 2009, European Journal of Nuclear Medicine and Molecular Imaging.

[14]  A. Alavi,et al.  PET and Parathyroid. , 2007, PET clinics.

[15]  L. Fig,et al.  11C-methionine PET/CT in 99mTc-sestamibi-negative hyperparathyroidism in patients with renal failure on chronic haemodialysis , 2006, European Journal of Nuclear Medicine and Molecular Imaging.

[16]  M. Pelizzo,et al.  Nuclear medicine and minimally invasive surgery of parathyroid adenomas: a fair marriage , 2003, European Journal of Nuclear Medicine and Molecular Imaging.

[17]  E. Hindié,et al.  Unilateral surgery for primary hyperparathyroidism on the basis of technetium Tc 99m sestamibi and iodine 123 subtraction scanning. , 2000, Archives of surgery.

[18]  M. O'Doherty,et al.  Technetium‐99m sestamibi parathyroid localization is accurate enough for scan‐directed unilateral neck exploration , 1996, The British journal of surgery.

[19]  D. Lowe,et al.  The accuracy of parathyroid gland localization in primary hyperparathyroidism using sestamibi radionuclide imaging. , 1996, The Journal of clinical endocrinology and metabolism.