The GDNF family: Signalling, biological functions and therapeutic value
暂无分享,去创建一个
[1] Masahide Takahashi,et al. Novel Mechanism of Regulation of Rac Activity and Lamellipodia Formation by RET Tyrosine Kinase* , 2002, The Journal of Biological Chemistry.
[2] B. Lu,et al. Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice. , 2002, American journal of human genetics.
[3] R. Korneluk,et al. IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo , 2002, Nature Cell Biology.
[4] C. Ibáñez,et al. Coordinated Activation of Autophosphorylation Sites in the RET Receptor Tyrosine Kinase , 2002, The Journal of Biological Chemistry.
[5] J. Milbrandt,et al. NGF Utilizes c-Ret Via a Novel GFL-Independent, Inter-RTK Signaling Mechanism to Maintain the Trophic Status of Mature Sympathetic Neurons , 2002, Neuron.
[6] M. Takahashi,et al. The GDNF/RET signaling pathway and human diseases. , 2001, Cytokine & growth factor reviews.
[7] Barbara L. Hempstead,et al. Regulation of Cell Survival by Secreted Proneurotrophins , 2001, Science.
[8] J. Engele,et al. Evidence for a ligand‐specific signaling through GFRα‐1, but not GFRα‐2, in the absence of Ret , 2001 .
[9] Steven W. Johnson,et al. GDNF acutely modulates excitability and A-type K+ channels in midbrain dopaminergic neurons , 2001, Nature Neuroscience.
[10] Xin Zhou,et al. Pericellular Griffonia simplicifolia I isolectin B4‐binding ring structures in the dorsal root ganglia following peripheral nerve injury in rats , 2001, The Journal of comparative neurology.
[11] J. Milbrandt,et al. RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons. , 2001, Development.
[12] E. Snyder,et al. Neuroprotection through Delivery of Glial Cell Line-Derived Neurotrophic Factor by Neural Stem Cells in a Mouse Model of Parkinson's Disease , 2001, The Journal of Neuroscience.
[13] Feng Yang,et al. Ca2+ Binding Protein Frequenin Mediates GDNF-Induced Potentiation of Ca2+ Channels and Transmitter Release , 2001, Neuron.
[14] L. Teng,et al. Overexpression of GDNF Induces and Maintains Hyperinnervation of Muscle Fibers and Multiple End-Plate Formation , 2001, Experimental Neurology.
[15] P. Aebischer,et al. Sustained delivery of GDNF: towards a treatment for Parkinson’s disease , 2001, Brain Research Reviews.
[16] H. Phillips,et al. Impaired water maze learning performance without altered dopaminergic function in mice heterozygous for the GDNF mutation , 2001, The European journal of neuroscience.
[17] A. Davies,et al. Multiple effects of artemin on sympathetic neurone generation, survival and growth. , 2001, Development.
[18] J. Milbrandt,et al. GDNF and neurturin are target-derived factors essential for cranial parasympathetic neuron development. , 2001, Development.
[19] M. Santoro,et al. The RET receptor: function in development and dysfunction in congenital malformation. , 2001, Trends in genetics : TIG.
[20] S. Kjær,et al. Molecular Modeling of the Extracellular Domain of the RET Receptor Tyrosine Kinase Reveals Multiple Cadherin-like Domains and a Calcium-binding Site* , 2001, The Journal of Biological Chemistry.
[21] V. D’Agati,et al. Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. , 2001, Genes & development.
[22] O. Lindvall,et al. Stroke induces widespread changes of gene expression for glial cell line-derived neurotrophic factor family receptors in the adult rat brain , 2001, Neuroscience.
[23] G. Feng,et al. Glial Cell Line-Derived Neurotrophic Factor Administration in Postnatal Life Results in Motor Unit Enlargement and Continuous Synaptic Remodeling at the Neuromuscular Junction , 2001, The Journal of Neuroscience.
[24] E. Mackenzie,et al. Neuroprotection Mediated by Glial Cell Line-Derived Neurotrophic Factor: Involvement of a Reduction of NMDA-Induced Calcium Influx by the Mitogen-Activated Protein Kinase Pathway , 2001, The Journal of Neuroscience.
[25] M. Saarma,et al. Human Glial Cell Line-derived Neurotrophic Factor Receptor α4 Is the Receptor for Persephin and Is Predominantly Expressed in Normal and Malignant Thyroid Medullary Cells* , 2001, The Journal of Biological Chemistry.
[26] Heidi Phillips,et al. Heparin Coinfusion during Convection-Enhanced Delivery (CED) Increases the Distribution of the Glial-Derived Neurotrophic Factor (GDNF) Ligand Family in Rat Striatum and Enhances the Pharmacological Activity of Neurturin , 2001, Experimental Neurology.
[27] D. Wright,et al. GDNF Rescues Nonpeptidergic Unmyelinated Primary Afferents in Streptozotocin-Treated Diabetic Mice , 2001, Experimental Neurology.
[28] G. Paratcha,et al. Released GFRα1 Potentiates Downstream Signaling, Neuronal Survival, and Differentiation via a Novel Mechanism of Recruitment of c-Ret to Lipid Rafts , 2001, Neuron.
[29] D. Katz,et al. Brain-Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor Are Required Simultaneously for Survival of Dopaminergic Primary Sensory Neurons In Vivo , 2001, The Journal of Neuroscience.
[30] R. Scott,et al. Determinants of Ligand Binding Specificity in the Glial Cell Line-derived Neurotrophic Factor Family Receptor αs* , 2001, The Journal of Biological Chemistry.
[31] Mu-ming Poo,et al. Neurotrophins as synaptic modulators , 2001, Nature Reviews Neuroscience.
[32] Feng Yang,et al. PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation , 2001, Nature Neuroscience.
[33] E. Nestler,et al. Molecular basis of long-term plasticity underlying addiction , 2001, Nature Reviews Neuroscience.
[34] J. Milbrandt,et al. Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin. , 2000, Development.
[35] M. Saarma,et al. GDNF FAMILY SIGNALLING IN EXOCRINE TISSUES: DISTINCT ROLES FOR GFRα1 AND GFRα2 IN DIFFERENT CRANIAL PARASYMPATHETIC GANGLIA. , 2000 .
[36] M. Saarma,et al. Distinct roles for GFRα1 and GFRα2 signalling in different cranial parasympathetic ganglia in vivo , 2000, The European journal of neuroscience.
[37] J. Bloch,et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. , 2000, Science.
[38] O. Lindvall,et al. Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor alpha 2. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[39] J. Epstein,et al. Pax3 is required for enteric ganglia formation and functions with Sox10 to modulate expression of c-ret. , 2000, The Journal of clinical investigation.
[40] P. Ernfors,et al. Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. , 2000, Development.
[41] M. Sanicola,et al. Developmental regulation of GDNF response and receptor expression in the enteric nervous system. , 2000, Development.
[42] J. Schlessinger. Cell Signaling by Receptor Tyrosine Kinases , 2000, Cell.
[43] S. McMahon,et al. Potent analgesic effects of GDNF in neuropathic pain states. , 2000, Science.
[44] G. Donnan,et al. Inhibition of brain‐derived neurotrophic factor and glial cell line‐derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum , 2000, The European journal of neuroscience.
[45] Kai Simons,et al. Lipid rafts and signal transduction , 2000, Nature Reviews Molecular Cell Biology.
[46] H. Schnürch,et al. Neurotrophin-3 promotes the cholinergic differentiation of sympathetic neurons. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[47] D. Bredesen,et al. The RET proto‐oncogene induces apoptosis: a novel mechanism for Hirschsprung disease , 2000, The EMBO journal.
[48] A. Hottinger,et al. Complete and Long-Term Rescue of Lesioned Adult Motoneurons by Lentiviral-Mediated Expression of Glial Cell Line-Derived Neurotrophic Factor in the Facial Nucleus , 2000, The Journal of Neuroscience.
[49] J. Livet,et al. GFRα1 Is Required for Development of Distinct Subpopulations of Motoneuron , 2000, The Journal of Neuroscience.
[50] R. Oppenheim,et al. Glial Cell Line-Derived Neurotrophic Factor and Developing Mammalian Motoneurons: Regulation of Programmed Cell Death Among Motoneuron Subtypes , 2000, The Journal of Neuroscience.
[51] M. Saarma,et al. Expression and Alternative Splicing of Mouse Gfra4 Suggest Roles in Endocrine Cell Development , 2000, Molecular and Cellular Neuroscience.
[52] David R Kaplan,et al. Neurotrophin signal transduction in the nervous system , 2000, Current Opinion in Neurobiology.
[53] A. Granholm,et al. Glial Cell Line-Derived Neurotrophic Factor Is Essential for Postnatal Survival of Midbrain Dopamine Neurons , 2000, The Journal of Neuroscience.
[54] I. Matsuoka,et al. Regulation of Glial Cell Line-Derived Neurotrophic Factor Responsiveness in Developing Rat Sympathetic Neurons by Retinoic Acid and Bone Morphogenetic Protein-2 , 2000, The Journal of Neuroscience.
[55] E. Nestler,et al. Role for GDNF in Biochemical and Behavioral Adaptations to Drugs of Abuse , 2000, Neuron.
[56] J. Milbrandt,et al. GFRα-Mediated Localization of RET to Lipid Rafts Is Required for Effective Downstream Signaling, Differentiation, and Neuronal Survival , 2000, Neuron.
[57] M. Saarma,et al. Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. , 2000, Science.
[58] J. Milbrandt,et al. Functional Mapping of Receptor Specificity Domains of Glial Cell Line-derived Neurotrophic Factor (GDNF) Family Ligands and Production of GFRα1 RET-specific Agonists* , 2000, The Journal of Biological Chemistry.
[59] Hideki Enomoto,et al. The GDNF family ligands and receptors — implications for neural development , 2000, Current Opinion in Neurobiology.
[60] S. McMahon,et al. Functional regeneration of sensory axons into the adult spinal cord , 2000, Nature.
[61] C. Xian,et al. Neurotrophins from dorsal root ganglia trigger allodynia after spinal nerve injury in rats , 2000, The European journal of neuroscience.
[62] S. McMahon,et al. The Glial Cell Line-Derived Neurotrophic Factor Family Receptor Components Are Differentially Regulated within Sensory Neurons after Nerve Injury , 2000, The Journal of Neuroscience.
[63] J. Thomas-Crusells,et al. GDNF triggers a novel Ret‐independent Src kinase family‐coupled signaling via a GPI‐linked GDNF receptor α1 , 1999, FEBS letters.
[64] J. Murray-Rust,et al. Distinct structural elements in GDNF mediate binding to GFRα1 and activation of the GFRα1–c‐Ret receptor complex , 1999 .
[65] Timothy Sendera,et al. Clinicopathological findings following intraventricular glial‐derived neurotrophic factor treatment in a patient with Parkinson's disease , 1999, Annals of neurology.
[66] J. Milbrandt,et al. Expression of Neurturin, GDNF, and GDNF Family-Receptor mRNA in the Developing and Mature Mouse , 1999, Experimental Neurology.
[67] M. Gershon,et al. Lessons from genetically engineered animal models. II. Disorders of enteric neuronal development: insights from transgenic mice. , 1999, The American journal of physiology.
[68] M. Gershon. II. Disorders of enteric neuronal development: insights from transgenic mice. , 1999, American journal of physiology. Gastrointestinal and liver physiology.
[69] E. Watson,et al. Nitric oxide acts independently of cGMP to modulate capacitative Ca2+ entry in mouse parotid acini. , 1999, American journal of physiology. Cell physiology.
[70] T. Shimazaki,et al. GFRα3, a Component of the Artemin Receptor, Is Required for Migration and Survival of the Superior Cervical Ganglion , 1999, Neuron.
[71] S. Whittemore,et al. Ret-dependent and -independent Mechanisms of Glial Cell Line-derived Neurotrophic Factor Signaling in Neuronal Cells* , 1999, The Journal of Biological Chemistry.
[72] E. Arenas,et al. Differential Effects of Glial Cell Line‐Derived Neurotrophic Factor and Neurturin on Developing and Adult Substantia Nigra Dopaminergic Neurons , 1999, Journal of neurochemistry.
[73] G. Raisman,et al. Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system. , 1999, Development.
[74] P. Ernfors,et al. A rapid and dynamic regulation of GDNF-family ligands and receptors correlate with the developmental dependency of cutaneous sensory innervation. , 1999, Development.
[75] X. Morin,et al. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives , 1999, Nature.
[76] M. Saarma,et al. GDNF Family Neurotrophic Factor Signaling: Four Masters, One Servant? , 1999, Molecular and Cellular Neuroscience.
[77] A. Ballabio,et al. Double heterozygosity for a RET substitution interfering with splicing and an EDNRB missense mutation in Hirschsprung disease. , 1999, American journal of human genetics.
[78] J. Holstege,et al. Depletion of GDNF from primary afferents in adult rat dorsal horn following peripheral axotomy. , 1999, Neuroreport.
[79] C. Ibáñez. Emerging themes in structural biology of neurotrophic factors , 1998, Trends in Neurosciences.
[80] R. Grondin,et al. Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson’s disease , 1998, Journal of Neurology.
[81] Y. Itoyama,et al. Reduction of ischemic brain injury by topical application of glial cell line-derived neurotrophic factor after permanent middle cerebral artery occlusion in rats. , 1998, Stroke.
[82] S. McMahon,et al. Tackling Pain at the Source: New Ideas about Nociceptors , 1998, Neuron.
[83] C. Henderson,et al. Synergistic Effects of Schwann- and Muscle-Derived Factors on Motoneuron Survival Involve GDNF and Cardiotrophin-1 (CT-1) , 1998, The Journal of Neuroscience.
[84] B. Hoffer,et al. Glial Cell Line-Derived Neurotrophic Factor Protects against Ischemia-Induced Injury in the Cerebral Cortex , 1997, The Journal of Neuroscience.
[85] P. Sargent,et al. Growth and morphogenesis of an autonomic ganglion. II. Establishment of neuron position , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[86] P. Sargent,et al. Growth and morphogenesis of an autonomic ganglion. I. Matching neurons with target , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[87] J. Epstein,et al. Pax 3 is required for enteric ganglia formation and functions with Sox 10 to modulate expression of cret , 2022 .