The Size of Blood–Brain Barrier Opening Induced by Focused Ultrasound is Dictated by the Acoustic Pressure
暂无分享,去创建一个
[1] Ankur Tyagi. Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB Opening , 2014, Annals of Neurosciences.
[2] Kullervo Hynynen,et al. Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound , 2013, Experimental Neurology.
[3] Paul S. Sheeran,et al. Targeted drug delivery with focus ultrasound-induced blood-brain barrier opening Using acoustically-activated nanodroplets , 2013, 2013 IEEE International Ultrasonics Symposium (IUS).
[4] K. Hynynen,et al. Noninvasive and targeted drug delivery to the brain using focused ultrasound. , 2013, ACS chemical neuroscience.
[5] T. Yen,et al. Noninvasive and Targeted Gene Delivery into the Brain Using Microbubble-Facilitated Focused Ultrasound , 2013, PloS one.
[6] M. Hennerici,et al. Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening , 2013, Molecular therapy. Nucleic acids.
[7] Natalia Vykhodtseva,et al. Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma. , 2012, Ultrasound in medicine & biology.
[8] D. Bihan,et al. Dynamic study of blood-brain barrier closure after its disruption using ultrasound: a quantitative analysis. , 2012 .
[9] Natalia Vykhodtseva,et al. Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. , 2012, Cancer research.
[10] James J. Choi,et al. Ultrasound-induced blood-brain barrier opening. , 2012, Current pharmaceutical biotechnology.
[11] James J. Choi,et al. Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood–brain barrier using focused ultrasound and microbubbles , 2012, Physics in medicine and biology.
[12] Kullervo Hynynen,et al. Blood-brain barrier: real-time feedback-controlled focused ultrasound disruption by using an acoustic emissions-based controller. , 2012, Radiology.
[13] Zhibiao Wang,et al. Targeted gene delivery to the mouse brain by MRI-guided focused ultrasound-induced blood–brain barrier disruption , 2012, Experimental Neurology.
[14] Yao-Sheng Tung,et al. The mechanism of interaction between focused ultrasound and microbubbles in blood-brain barrier opening in mice. , 2011, The Journal of the Acoustical Society of America.
[15] V. Ferrera,et al. Feasibility of noninvasive cavitation-guided blood-brain barrier opening using focused ultrasound and microbubbles in nonhuman primates. , 2011, Applied physics letters.
[16] Wayne Kreider,et al. Blood vessel deformations on microsecond time scales by ultrasonic cavitation. , 2011, Physical review letters.
[17] Cheri X Deng,et al. Targeted drug delivery across the blood-brain barrier using ultrasound technique. , 2010, Therapeutic delivery.
[18] K. Hynynen,et al. Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats , 2010, BMC neurology.
[19] Yao-Sheng Tung,et al. In vivo transcranial cavitation threshold detection during ultrasound-induced blood–brain barrier opening in mice , 2010, Physics in medicine and biology.
[20] James J. Choi,et al. In vivo transcranial cavitation detection during ultrasound-induced blood-brain barrier opening , 2010, 2010 IEEE International Ultrasonics Symposium.
[21] Yao-Sheng Tung,et al. Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study. , 2010, Ultrasound in medicine & biology.
[22] Rajiv Chopra,et al. Antibodies Targeted to the Brain with Image-Guided Focused Ultrasound Reduces Amyloid-β Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease , 2010, PloS one.
[23] M. Hennerici,et al. Reorganization of Gap Junctions after Focused Ultrasound Blood–Brain Barrier Opening in the Rat Brain , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[24] R. Gabathuler,et al. Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases , 2010, Neurobiology of Disease.
[25] Kullervo Hynynen,et al. Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. , 2008, Ultrasound in medicine & biology.
[26] K. Hynynen,et al. Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models , 2008, PloS one.
[27] Manabu Kinoshita,et al. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[28] Nico de Jong,et al. Vibrating microbubbles poking individual cells: drug transfer into cells via sonoporation. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[29] K. Hynynen,et al. Targeted disruption of the blood–brain barrier with focused ultrasound: association with cavitation activity , 2006, Physics in medicine and biology.
[30] Natalia Vykhodtseva,et al. MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. , 2005, Ultrasound in medicine & biology.
[31] K. Hynynen,et al. Targeted disruption of the blood-brain barrier with focused ultrasound: association with inertial cavitation , 2005, IEEE Ultrasonics Symposium, 2005..
[32] K. Hynynen,et al. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. , 2004, Ultrasound in medicine & biology.
[33] Akira Tsuji,et al. Drug delivery through the blood-brain barrier , 1996 .
[34] L. Lebrun,et al. Diffusion of dextran through microporous membrane filters , 1994 .
[35] M. Danhof,et al. Drug transport across the blood-brain barrier , 1992, Pharmaceutisch Weekblad.
[36] S. Rapoport,et al. Size selectivity of blood-brain barrier permeability at various times after osmotic opening. , 1987, The American journal of physiology.
[37] D. Heistad,et al. Permeability of blood-brain barrier to various sized molecules. , 1985, The American journal of physiology.
[38] Yao-Sheng Tung,et al. Microbubble-Size Dependence of Focused Ultrasound-Induced Blood–Brain Barrier Opening in Mice In Vivo , 2010, IEEE Transactions on Biomedical Engineering.
[39] Yao-Sheng Tung,et al. Molecules of various pharmacologically-relevant sizes can cross the ultrasound-induced blood-brain barrier opening in vivo. , 2010, Ultrasound in medicine & biology.
[40] James J. Choi,et al. Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice. , 2007, Ultrasound in medicine & biology.