Better than real: Complex-valued neural nets for MRI fingerprinting

The task of MRI fingerprinting is to identify tissue parameters from complex-valued MRI signals. The prevalent approach is dictionary based, where a test MRI signal is compared to stored MRI signals with known tissue parameters and the most similar signals and tissue parameters retrieved. Such an approach does not scale with the number of parameters and is rather slow when the tissue parameter space is large. Our first novel contribution is to use deep learning as an efficient nonlinear inverse mapping approach. We generate synthetic (tissue, MRI) data from an MRI simulator, and use them to train a deep net to map the MRI signal to the tissue parameters directly. Our second novel contribution is to develop a complex-valued neural network with new cardioid activation functions. Our results demonstrate that complex-valued neural nets could be much more accurate than real-valued neural nets at complex-valued MRI fingerprinting.

[1]  Kazuyuki Murase,et al.  Single-layered complex-valued neural network for real-valued classification problems , 2009, Neurocomputing.

[2]  W. Wirtinger Zur formalen Theorie der Funktionen von mehr komplexen Veränderlichen , 1927 .

[3]  J. Hennig,et al.  Pseudo Steady‐State Free Precession for MR‐Fingerprinting , 2017, Magnetic resonance in medicine.

[4]  D. Louis Collins,et al.  A new improved version of the realistic digital brain phantom , 2006, NeuroImage.

[5]  Yong Chen,et al.  Multiscale reconstruction for MR fingerprinting , 2016, Magnetic resonance in medicine.

[6]  Francesco Piazza,et al.  On the complex backpropagation algorithm , 1992, IEEE Trans. Signal Process..

[7]  D. Louis Collins,et al.  Design and construction of a realistic digital brain phantom , 1998, IEEE Transactions on Medical Imaging.

[8]  Trevor Darrell,et al.  Caffe: Convolutional Architecture for Fast Feature Embedding , 2014, ACM Multimedia.

[9]  Kawin Setsompop,et al.  Fast group matching for MR fingerprinting reconstruction , 2015, Magnetic resonance in medicine.

[10]  Tohru Nitta,et al.  An Extension of the Back-Propagation Algorithm to Complex Numbers , 1997, Neural Networks.

[11]  Ken Kreutz-Delgado,et al.  The Complex Gradient Operator and the CR-Calculus ECE275A - Lecture Supplement - Fall 2005 , 2009, 0906.4835.

[12]  Yun Jiang,et al.  SVD Compression for Magnetic Resonance Fingerprinting in the Time Domain , 2014, IEEE Transactions on Medical Imaging.

[13]  Cris Koutsougeras,et al.  Complex domain backpropagation , 1992 .

[14]  J. Duerk,et al.  Magnetic Resonance Fingerprinting , 2013, Nature.

[15]  B. A. D. H. Brandwood A complex gradient operator and its applica-tion in adaptive array theory , 1983 .